李嘉宾 - 中国药科大学

个人简介

李嘉宾，男，1972年8月生，副教授，硕士生导师。2006年博士毕业于中国药科大学药学院药物化学专业。2013-2014年赴美 University of California at Santa Barbara 化学与生物化学系研修，开展过渡金属催化的有机合成方法学研究。已发表研究性论文17篇，其中SCI源论文10篇，申请专利1项。参与国家863项目《一类抗高血压新药盐酸菲洛普的研究》等三项纵向课题研究，承担两项企业委托项目。

研究领域

1.治疗良性前列腺增生药物及心血管病药物的研究。 2.以GPCR为靶标的活性小分子的设计、合成、生物活性及构效关系研究。 3.过渡金属催化的合成方法学研究

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

(1) Jiabin LI, Kegong JI, Renhua ZHENG, Jonathan NELSON and Liming ZHANG* Expanding the horizon of intermolecular trapping of in situ generated α-oxo gold carbenes: efficient oxidative union of allylic sulfides and terminal alkynes via C–C bond formation Chem. Commun., 2014,50, 4130-4133 DOI: 10.1039/C4CC00739E (2) Jun XIA, Jiabin LI*, Hongbin SUN* Insights into ETA subtype selectivity of benzodiazepine endothelin receptor antagonists by 3D-QSAR approaches J. Mol. Model, 2012, 18(4): 1299-1322, DOI 10.1007/s00894-011-1153-x (3) Lutai WANG, Jiabin LI, Xiaowen XUE* A concise synthesis of ximenynic acid Synth. Commun. 2012, 42, 3540-3543, DOI 10.1080/00397911.2011.585443 (4) Jiabin LI, HaichunLIU, Li ZHANG, Tao WANG, Zhenzhou JIANG, Lin XIA*, Searching for the novel lead compounds of α1-AR antagonists (Part II): synthesis, bioassays and 3D-QSAR of 2-(4-(Aryloxyalkyl)-piperazin-1-yl)benzo[d]oxazole compounds Chem. J. Chinese U., 2009, 30(5): 903-907 (5) Jiabin LI, Zhenzhou JIANG, Tao WANG, Mingming LIU, Jun XIA, Lin XIA, Searching for the novel lead compounds of α1-AR antagonists (Part I): design, synthesis and bioassay of 5-Chloro-2-[4-(aryloxyalkyl)piperazin-1-yl]benzo[d]oxazole compounds Acta Chimica Sinica, 2008, 66(24): 2725-2729 (6) Jiabin LI, Lin XIA*, Bin Wu, Tao Wang, Zhenzhou Jiang Design, synthesis and biological estimation of 1-(Benzoxazole-2-yl) piperazine and 4-(Benzoxazole-2-yl) piperidine derivatives as potential α1-AR antagonists Chinese Chem. Lett. 2008, 19(10), 1193-1195 (7) Jiabin LI, Lin XIA*, Yadong CHEN A 3D pharmacophore model of α1A-adrenoceptor antagonists Acta Chimica Sinica, 2007, 65 (16): 1621-1630 (8) Jiabin LI, Pin YANG*, Fei GAO, Gaoyi HAN, Kaibei YU Novel lanthanide complexes of ciprofloxacin: synthesis, characterization, crystal structure and in vitro antibacterial activity studies Chinese J.Chem., 2001,19 (6), 598-605 (9) Pin YANG*, Jiabin LI, Yanni TIAN Synthesis and crystal structure of rare earth complex with ciprofloxacin Chinese Chem. Lett., 1999, 10 (10), 879-880