个人简介
2002.09-2006.06，湖南大学，生物技术专业，理学学士
2006.09-2009.06，南京工业大学，药物化学专业，理学硕士
2009.09-2012.06，中国药科大学，药物化学专业，理学博士
2012.06-2015.09，江南大学，药学院，讲师
2015.09至今，江南大学，药学院，副教授，硕士生导师
近期论文
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1. Zhou Y, Zhu X, Zhang L, Tang C*, Feng B. Design, synthesis and biological evaluation of 2-(4-(methylsulfonyl)phenyl)pyridine derivatives as GPR119 agonists. Chemical biology & drug design[J]. 2019, 93(1): 67-74.
2. Zhao H, Hu X, Cao K, Zhang Y, Zhao K, Tang C*, Feng B. Synthesis and SAR of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as potent and selective CDK4/6 inhibitors. European Journal of Medicinal Chemistry. 2018, 157: 935-945.
3. Hu X, Zhao H, Wang Y, Liu Z, Feng B, Tang C*. Synthesis and biological evaluation of novel 5, 6-dihydropyrimido [4, 5-f] quinazoline derivatives as potent CDK2 inhibitors. Bioorganic & medicinal chemistry letters. 2018, 28(20): 3385-3390.
4. Chen Z, Tang C, Zhu Y, et al. TrpC5 regulates differentiation through the Ca2+/Wnt5a signalling pathway in colorectal cancer[J]. Clinical Science, 2017, 131(3): 227-237.
5. Wang G, Tang C, Yan G, Feng B. Gene expression profiling of H9c2 cells subjected to H2O2-induced apoptosis with/without AF-HF001.[J]. Biological & Pharmaceutical Bulletin, 2016, 39(2):207-214.
6. Tang C, Xie D, Feng B. Zebrafish as a New Model for Phenotype‐based Screening of Positive Inotropic Agents[J]. Chemical biology & drug design, 2015, 85(3): 253-258.
7. Tang C, Gu G, Yang B, et al. Synthesis and In Vivo Hepatoprotective Activity of Some Novel Andrographolide Derivatives[J]. Letters in Drug Design & Discovery, 2014, 11(5): 677-685.
8. Tang C, Gu G, Wang B, et al. Design, Synthesis, and Biological Evaluation of Andrographolide Derivatives as Potent Hepatoprotective Agents[J]. Chemical biology & drug design, 2014, 83(3): 324-333.
9. Tang C, Chen S, Qian H, et al. Interleukin‐23: as a drug target for autoimmune inflammatory diseases[J]. Immunology, 2012, 135(2): 112-124.
10. Tang C, Zhu X, Huang D, et al. A specific pharmacophore model of sodium-dependent glucose co-transporter 2 (SGLT2) inhibitors[J]. Journal of molecular modeling, 2012, 18(6): 2795-2804.
11. Tang C, Liu Y, Wang B, et al. Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti‐HIV Agents[J]. Archiv der Pharmazie, 2012, 345(8): 647-656.
12. Tang C, Zhang W, Wang X, et al. Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Antibacterial Agents[J]. Letters in Drug Design & Discovery, 2011, 8(9): 816-821.
13. Wang B, Tang C (co-first author), Han Y, et al. Synthesis and preliminary antihyperlipidaemic activities evaluation of andrographolide derivatives[J]. Medicinal Chemistry, 2012, 8(2): 293-298.
14. Zhu X, Huang D, Lan X,Tang C, et al. The first pharmacophore model for potent G protein-coupled receptor 119 agonist[J]. European journal of medicinal chemistry, 2011, 46(7): 2901-2907.
15. Zhu X, Ji J, Huang D, Zhu Y, Tang C,et al. Discovery, Synthesis and Evaluation of Novel Cholesterol Absorption Inhibitors[J]. Chemical biology & drug design, 2012, 80(3): 426-433.
16. Huang D, Zhu X, Tang C, et al. 3D QSAR Pharmacophore Modeling for c-Met Kinase Inhibitors[J]. Medicinal Chemistry, 2012, 8(6): 1117-1125.
17. Lan X, Lin H, Tang C, et al. Evaluation of In-Vitro Multidrug Resistance Reversal Activities of HZ08 analogues with Improved Soluble Property[J]. Letters in Drug Design & Discovery, 2013, 10(1): 56-60.
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