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Zhou L*, Huang X, Niesvizky R, Pu Z, Xu G*. Caspase-8 regulates the anti-myeloma activity of bortezomib and lenalidomide. J Pharmacol Exp Ther, 2021, JPET-AR-2021-000818.
Zhang Z, Cheng X, Jiang H, Gu J, Yin Y, Shen Z, Xu C, Pu Z, Li J-B*, Xu G*. Quantitative proteomic analysis of glycosylated proteins enriched from urine samples with magnetic ConA nanoparticles identifies potential biomarkers for small cell lung cancer. J Pharm Biomed Anal, 2021, 206, 114352.
Lu J, Jiang H, Li D, Chen T, Wang Y, Pu Z*, Xu G*. Proximity labeling, quantitative proteomics, and biochemical studies revealed the molecular mechanism for the inhibitory effect of indisulam on the proliferation of gastric cancer cells. J. Proteome Res.2021, 20(9), 4462-4474.
Zhang Y, Zha Z, Shen W, Li D, Kang N, Chen Z, Liu Y, Xu G*, Xu Q* Anemoside B4 ameliorates TNBS‑induced colitis through S100A9/MAPK/NF‑κB signaling pathway. Chin. Med.2021, 16(1), 11.
Hu Z, Wang X, Li D, Cao L, Cui H, Xu G*. UFBP1, a key component in ufmylation, enhances drug sensitivity by promoting proteasomal degradation of oxidative stress-response transcription factor Nrf2. Oncogene2021, 40, 647-662.
Yu W, Wang B, Zhou L*, Xu G*. Endoplasmic reticulum stress-mediated p62 downregulation inhibits apoptosis via c-Jun upregulation. Biomol. Ther.2021, 29(2), 195-204.
Zhou L, Yu W, Jayabalan DS, Niesvizky R, Jaffrey SR, Huang X*, Xu G*. Caspase-8 inhibition prevents the cleavage and degradation of E3 ligase substrate receptor cereblon and potentiates its biological function. Front. Cell Dev. Biol.2020, 8, 605989.
Ullah K, Chen S, Lu J, Wang X, Liu Q, Zhang Y, Long Y, Hu Z*, Xu G*. The E3 ubiquitin ligase STUB1 attenuates cell senescence by promoting the ubiquitination and degradation of the core circadian regulator BMAL1. J. Biol. Chem.2020, 295(14), 4696-4708.
Yuan Y#, Miao Y#, Qian L, Zhang Y, Liu C, Liu J, Zuo Y, Feng Q, Guo T, Zhang L, Chen X, Jin L, Huang F, Zhang H, Zhang W, Li W, Xu G, Zheng H*. Targeting UBE4A revives viperin protein in epithelium to enhance host antiviral defense. Mol. Cell2020, 77(4), 734-747.e7.
Duan Q, Li D, Xiong L, Chang Z, Xu G*. SILAC quantitative proteomics and biochemical analyses reveal a novel molecular mechanism by which ADAM12S promotes the proliferation, migration, and invasion of small cell lung cancer cells through upregulating hexokinase 1. J. Proteome Res.2019, 18, 2903-2914.
Guo Q, Zhu Q, Miao T, Tao J, Ju X, Sun Z, Li H, Xu G, Chen H, Han L. LRP1-upregulated nanoparticles for efficiently conquering the blood-brain barrier and targetedly suppressing multifocal and infiltrative brain metastases. J. Control Release2019, 303, 117-129.
Zhou L, Xu G*. Cereblon attenuates DNA damage-induced apoptosis by regulating the transcription-independent function of p53. Cell Death Dis.2019, 10, 69.
Ullah K, Zubia E, Narayan M, Yang J, Xu G*. Diverse roles of the E2/E3 hybrid enzyme UBE2O in the regulation of protein ubiquitination, cellular functions, and disease onset. FEBS J.2019, 286, 2018-2034 (Review, Cover Story).
Chen S#, Yang J#, Zhang Y, Duan C, Liu Q, Huang Z, Xu Y, Zhou L*, Xu G*. Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1. J. Biol. Chem.2018, 293, 11296-11309 (Cover Story).
Yang J#, Huang M#, Zhou L, He X, Jiang X, Zhang Y, Xu G*. Cereblon suppresses lipopolysaccharide-induced inflammatory response through promoting the ubiquitination and degradation of c-Jun. J. Biol. Chem.2018, 293, 10141-10157.
Zhang Y#, Duan C#, Yang J, Chen S, Liu Q, Zhou L, Huang Z, Xu Y, Xu G*.Deubiquitinating enzyme USP9X regulates cellular clock function by modulating the ubiquitination and degradation of a core circadian protein BMAL1. Biochem. J.2018, 475, 1507-1522. (#: co-first authors).
Zhu Y#, Lei Q#, Li D, Zhang Y, Jiang X, Hu Z, Xu G*. Proteomic and biochemical analyses reveal a novel mechanism for promoting protein ubiquitination and degradation by UFBP1, a key component of ufmylation. J. Proteome Res.2018, 17, 1509-1520.
Zhou L, Hao Z, Wang G, Xu G*. Cereblon suppresses the formation of pathogenic protein aggregates in a p62-dependent manner. Hum. Mol. Genet.2018, 27, 667-678.
Zhang L, Yang H, Zhang W, Liang Z, Huang Q, Xu G, Zhen X*, Zheng LT*. Clk1-regulated aerobic glycolysis is involved in glioma chemoresistance. J. Neurochem.2017, 142, 574-588.
Chu M, Li T, Shen B, Cao X, Zhong H, Zhang L, Zhou F, Ma W, Jiang H, Xie P, Liu Z, Dong N, Xu Y, Zhao Y, Xu G, Lu P, Luo J, Wu Q, Alitalo K, Koh GY, Adams RH, He Y*. Angiopoietin receptor Tie2 is required for vein specification and maintenance via regulating COUP-TFII. eLife2016, 5, e21032.
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