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个人简介

蒋善群,博士,教授,博士生导师,安徽大学生物统计系主任,安徽省高校学科(专业)拔尖人才,安徽省学科带头人后备人选,合肥市十大优秀青年,中国药理学会会员,中国药理精准分析委员会青年委员。 教育经历: 2013-2014 美国弗吉尼亚大学医学院,访问学者 2003-2005 美国哈佛大学公共卫生学院,研究学者 1999-2005 中国科学技术大学生命科学学院硕博连读,博士 1994-1998 安徽大学生物系生物化学专业,学士 工作经历: 2018-现在 安徽大学生命科学学院 教授 2017-现在 安徽大学生物统计学系 主任 2007-2018 安徽大学生命科学学院 副教授 2005-2007 安徽医科大学生物医学研究所 副研究员 2005-2007 安徽医科大学生物医学研究所分子医学中心 主任

研究领域

主要心脑血管疾病精准医学、药物基因组学、遗传流行病学及分子医学遗传学。

近期论文

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Tao F, Weinstock J, Venners SA, Cheng J, Hsu YH, Zou Y, Pan F, Jiang S*, Zha X, Xu X. Associations of the ABCA1 and LPL Gene Polymorphisms With Lipid Levels in a Hyperlipidemic Population. Clin Appl Thromb Hemost.2018;24(5):771-779. Cheng J, Tao F, Liu Y, Venners SA, Hsu YH, Jiang S*, Weinstock J, Wang B, Tang G, Xu X. Associations of methylenetetrahydrofolate reductase C677T genotype with blood pressure levels in Chinese population with essential hypertension. Clin Exp Hypertens. 2018;40(3):207-212. Liu Y, Kong X, Wang W, Fan F, Zhang Y, Zhao M, Wang Y, Wang Y, Wang Y, Qin X, Tang G, Wang B, Xu X, Hou FF, Gao W, Sun N, Li J, Venners SA, Jiang S*, Huo Y. Association of Peripheral Differential Leukocyte Counts with Dyslipidemia Risk in Chinese Patients with Hypertension: Insight from the CSPPT. J Lipid Res. 2017;58(1):256-266. Jiang S*, Venners SA, Li K, Hsu YH, Weinstock J, Zou Y, Pan F, Xu X. Effect modification by region in the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced CK elevation. Oncotarget. 2017;8(64):107565-107576. Jiang S, Li J, Zhang Y, Venners SA, Tang G, Wang Y, Li Z, Xu X, Wang B, Huo Y. Methylenetetrahydrofolate reductase C677T polymorphism, hypertension and risk of stroke: a prospective, nested case-control study. Int J Neurosci. 2017;127(3):253-260. Jiang S*, Venners SA, Hsu YH, Weinstock J, Wang B, Xing H, Wang X, Xu X. Interactive Effect of the KCNJ11 Ile337Val Polymorphism and Cigarette Smoking on the Antihypertensive Response to Irbesartan in Chinese Hypertensive Patients. Am J Hypertens. 2016; 29(5):553-9. Li K, Liu Y, Venners SA, Hsu YH, Jiang S*, Weinstock J, Sun Y, Wang B, Xu X. Effects of LEP G2548A and LEPR Q223R Polymorphisms on Serum Lipids and Response to Simvastatin Treatment in Chinese Patients With Primary Hyperlipidemia. Clin Appl Thromb Hemost. 2017;23(4):336-344. Liu Y, Li K, Venners SA, Hsu YH, Jiang S*, Weinstock J, Wang B, Tang G, Xu X. Individual and Joint Associations of Methylenetetrahydrofolate Reductase C677T Genotype and Plasma Homocysteine With Dyslipidemia in a Chinese Population With Hypertension. Clin Appl Thromb Hemost. 2017;23(3):287-293. Jiang S*, Pan M, Wu S, Venners SA, Zhong G, Hsu Y, Weinstock J, Xu X. Elevation in Total Homocysteine Levels in Chinese Patients With Essential Hypertension Treated With Antihypertensive Benazepril. Clin Appl Thromb Hemost. 2016; 22(2):191-8. Jiang S*, Zhao R, Pan M, Venners SA, Zhong G, Hsu YH. Associations of MTHFR and MTRR Polymorphisms With Serum Lipid Levels in Chinese Hypertensive Patients. Clin Appl Thromb Hemost. 2014;20(4):400-10. Wang Y, Xu X, Huo Y, Liu D, Cui Y, Liu Z, Zhao Z, Xu X, Liu L, Li X, Jiang S*. Predicting Hyperhomocysteinemia by Methylenetetrahydrofolate Reductase C677T Polymorphism in Chinese Patients With Hypertension. Clin Appl Thromb Hemost. 2015;21(7):661-6. Jiang S*, Chen Q, Venners SA, Zhong G, Hsu YH, Xing H, Wang X, Xu X. Effect of simvastatin on plasma homocysteine levels and its modification by MTHFR C677T polymorphism in Chinese patients with primary hyperlipidemia. Cardiovasc Ther. 2013;31(4):e27-33. Jiang S*, Hsu YH, Venners SA, Zhang Y, Xing H, Wang X, Xu X. Interactive Effect of Angiotensin II Type 1 Receptor (AGT1R) Polymorphisms and Plasma Irbesartan Concentration on Antihypertensive Therapeutic Responses to Irbesartan. J Hypertens. 2011; 29(5): 890-5. Jiang S*, Hsu YH, Venners SA, Zhang Y, Xing H, Wang X, Xu X. Effects of protein coding polymorphisms in the kallikrein 1 gene on baseline blood pressure and antihypertensive response to irbesartan in Chinese hypertensive patients. J Hum Hypertens. 2011; 25(5): 327-33. Jiang S*, Yu Y, Venners SA, Zhang Y, Xing H, Wang X, Xu X. Effects of MTHFR and MS gene polymorphisms on baseline blood pressure and Benazepril effectiveness in Chinese hypertensive patients. J Hum Hypertens. 2011; 25(3):172-7. Chen QR, Jiang SQ*, Xu XP. Polymorphism of genes encoding homocysteine metabolism-related enzymes and risk for cardio-cerebrovascular disease. Zhonghua Xin Xue Guan Bing Za Zhi. 2012;40(9):801-3. Jiang SQ*, Xu XP. Pharmacogenomics of renin angiotensin system inhibitors. Zhonghua Xin Xue Guan Bing Za Zhi. 2010;38(1):90-3. Jiang S*, Mao G, Zhang S, Hong X, Tang G, Li Z, Liu X, Zhang Y, Wang B, Xu X, Wang X. Individual and joint association of alpha1A-adrenergic receptor Arg347Cys polymorphism and plasma irbesartan concentration with blood pressure therapeutic response in Chinese hypertensive subjects. Clin Pharmacol Ther. 2005;78(3):239-48. Jiang S, Hsu YH, Niu T, Xu X, Xing H, Chen C, Wang X, Zhang Y, Peng S, Xu X. A common haplotype on methylenetetrahydrofolate reductase gene modifies the effect of angiotensin-converting enzyme inhibitor on blood pressure in essential hypertension patients--a family-based association study. Clin Exp Hypertens. 2005;27(6):509-21. Jiang S, Hsu YH, Xu X, Xing H, Chen C, Niu T, Zhang Y, Peng S, Xu X. The C677T polymorphism of the methylenetetrahydrofolate reductase gene is associated with the level of decrease on diastolic blood pressure in essential hypertension patients treated by angiotensin-converting enzyme inhibitor. Thromb Res. 2004;113(6):361-9.

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