研究领域
1,糖生物工程（功能碳水化合物的绿色生物制造、分离纯化及功能评价）；
2,分离工程（膜和色谱分离技术及其在糖工程、生物制造中的应用）；
3,生物基材料工程（新型生物基材料开发、纳米生物基材料及其在食品医药应用）
4,功能发酵与酿造食品研究与开发。
近期论文
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Mengyao Zhao, Liming Gu, Yun Li, Shumin Chen, Jiangshan You, Liqiang Fan, Yudong Wang,Liming Zhao*. Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways.Carbohydrate Polymers. 9 August 2019, 115171
Zhen Qin#, Si Lin#, Yongjun Qiu, Qiming Chen, Yin Zhang, Jiachun Zhou,Liming Zhao*. One-step immobilization-purification of enzymes by carbohydrate-binding module family 56 tag fusion[J].Food Chemistry, Volume 299, 30 November 2019, 125037.
Si Lin#, Zhen Qin#, Qiming Chen, Liqiang Fan, Jiachun Zhou,Liming Zhao*. Efficient immobilization of bacterial GH family 46 chitosanase by carbohydrate-binding module fusion for the controllable preparation of chitooligosaccharides[J].Journal of agricultural and food chemistry, 2019, 67(24): 6847-6855.
Jun Lu#, Qiming Chen#, Bolin Pan, Zhen Qin, Liqiang Fan, Quanming Xia,Liming Zhao*. Efficient inhibition of Cronobacter biofilms by chitooligosaccharides of specific molecular weight[J].World Journal of Microbiology and Biotechnology, 2019, 35(6): 87.
Qiming Chen, Lu Jun, Yongjun Qiu,Liming Zhao*. Bioinformatics-based mining of novel gene targets for identification of Cronobacter turicensis using PCR[J].Journal of dairy science, 2019, 102(7): 6023-6026.
Sijing Jiang,Liqiang Fan*, Mengyao Zhao, Yongjun Qiu,Liming Zhao*. Enhanced Low Molecular Weight Poly-γ-Glutamic Acid Production in Recombinant Bacillus subtilis 1A751 with Zinc Ion[J].Applied biochemistry and biotechnology, 2019.https://doi.org/10.1007/s12010-019-03004-2.
Yang Zhang, Liqiang Fan, Mengyao Zhao, Qiming Chen, Zhen Qin, Zhihang Feng, Toru Fujiwara,Liming Zhao*. Chitooligosaccharide plays essential roles in regulating proline metabolism and cold stress tolerance in rice seedlings[J].Acta Physiologiae Plantarum, 2019, 41(6): 77.
Ping Chen, Mengyao Zhao, Qiming Chen, Liqiang Fan, Feng Gao, andLiming Zhao*，Absorption Characteristics of Chitobiose and Chitopentaose in the Human Intestinal Cell Line Caco-2 and Everted Gut Sacs，Journal of Agricultural and Food Chemistry，2019，67 (16)：4513-4523.
Mengyao Zhao, Xin Shen, Xiaodan Li, Baoli Chen, Liqiang Fan, Quanming Xia,Liming Zhao*，Chitooligosaccharide supplementation prevents the development of high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in mice via the inhibition of cluster of differentiation 36 (CD36)，Journal of Functional Foods, 57 (2019):7–18
Jiachun Zhou，Qiao Chen, Yang Zhang, Liqiang Fan, Zhen Qin,Qiming Chen, Yongjun Qiu, Lihua Jiang* andLiming Zhao*，Chitooligosaccharides enhance cold tolerance by repairing photodamaged PS II in rice，The Journal of Agricultural Science，2018,156: 888–899.
Wei Li，Mengyao Zhao，Zhen Qin，Qiming Chen，Liqiang Fan，Jiachun Zhou，Liming Zhao*，Inhibitory effect of chitooligosaccharides on retinol metabolism and bioavailability in mice，J Food Biochem. 2019,43(3):1-10.
Lei Yao, Zhen Qin, Qiming Chen, Mengyao Zhao, Hefei Zhao, Waheed Ahmad, Liqiang Fan,Liming Zhao*, Insights into the nanofiltration separation mechanism of monosaccharides by molecular dynamics simulation,Separation and Purification Technology,205 (2018) :48–57.
Xiaodan Li#, Mengyao Zhao#, Liqiang Fan, Xuni Cao, Liehuan Chen, Junhui Chen, Y. Martin Lo,Liming Zhao*, Chitobiose alleviates oleic acid-induced lipid accumulation by decreasing fatty acid uptake and triglyceride synthesis in HepG2 cells,Journal of Functional Foods, 46 (2018): 202-211.
Zhen Qin, Sa Luo, Yun Li, Qiming Chen, Yongjun Qiu,Liming Zhao∗, Lihua Jiang, Jiachun Zhou, Biochemical properties of anovelchitosanase from Bacillus amyloliquefaciens and its use in membrane reactor.LWT - Food Science and Technology, 97 (2018): 9–16.
Xiaoxing Yang, Jiachun Zhou, Liqiang Fan, Zhen Qin, Qiming Chen,Liming Zhao*. Antioxidant properties of a vegetable–fruit beverage fermented with two Lactobacillus plantarum strains.Food Science and Biotechnology, (2018) 27(6): 1719–1726.
Li-Qiang Fan*, Ming-Wei Li, Yong-jun Qiu, Qi-ming Chen, Si-Jing Jiang, Yu-Jie Shang,Li-Ming Zhao*, Increasing thermal stability of glutamate decarboxylase from Escherichia. coli by site-directed saturation mutagenesis and its application in GABA production.Journal of Biotechnology, 278 (2018): 1–9.
Zhen Qin, Qiming Chen，Si Lin，Sa Luo，Yongjun Qiu，Liming Zhao*.Expression and characterization of a novel cold‑adapted chitosanase suitable for chitooligosaccharides controllable preparation.Food Chemistry, 253 (2018): 139–147.
Sha Huang,Liming Zhao*, Qiming Chen, Zhen Qin, Jiachun Zhou, Yongjun Qiu, Yin Zhang, Mingyue Ma, Physicochemical Characteristics of Edible Bird’s Nest Proteins and Their Cooking Processing Properties.International Journal of Food Engineering.2018;20170152.
Qiming CHEN, Yang ZHU, Zhen QIN, Yongjun QIU,Liming ZHAO*,Cronobacter spp., foodborne pathogens threatening neonates and infants,Front. Agr. Sci. Eng. 2018, 5 (3): 330-339.
Ye Sun, Zhen Qing,Liming Zhao*, Qiming Chen, Qingyun Hou, Hua Lin, Lihua Jiang, Jinchang Liu, Zheng Du. Membrane fouling mechanisms and permeate flux decline model in soy sauce microfiltration.J Food Process Eng.41(1),2018:1-10.
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