张振中 - 郑州大学 - 河南省肿瘤重大疾病靶向治疗与诊断重点实验室

个人简介

2000.07-至今，郑州大学，药学院，教授 2002.04-2003.04，瑞典卡洛琳斯卡医学院，博士后 1996.07-2000.07，河南医科大学，药学系，副教授 1996.09-1999.06，中国药科大学，药物分析，博士 1990.07-1996.09，河南医科大学，公共卫生学院，讲师 1987.09-1990.06，河南医科大学，卫生化学，硕士 1983.09-1987.06，河南大学，化学，学士荣誉称号及奖励国家有突出贡献中青年专家河南省优秀专家河南省优秀教师河南省中青年骨干教师河南省杰出青年基金获得者河南省杰出科技创新人才国家人事部优秀留学回国人员河南省高等学校创新人才培养对象河南省高校杰出科研人才

研究领域

靶向药物转运载体的构建;新型药物制剂研究；纳米药物体内行为与靶向转运机制;肿瘤早期诊断及液体活检新策略

近期论文

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Hou, L., X. Shan, L. Hao, Q. Feng and Z. Zhang (2017). "Copper sulfide nanoparticle-based localized drug delivery system as an effective cancer synergistic treatment and theranostic platform." Acta Biomater 54: 307-320. Guo, X., C. Chen, X. Liu, P. Hou, X. Guo, F. Ding, Z. Wang, Y. Hu, Z. Li and Z. Zhang (2017). "High oral bioavailability of 2-methoxyestradiol in PEG-PLGA micelles-microspheres for cancer therapy." Eur J Pharm Biopharm. Liu, Y., D. Li, X. Guo, H. Xu, Z. Li, Y. Zhang, C. Song, R. Fan, X. Tang and Z. Zhang (2017). "A pH-responsive prodrug delivery system of 10-HCPT for controlled release and tumor targeting." Int J Nanomedicine 12: 2227-2242 Wang, L., D. Li, Y. Hao, M. Niu, Y. Hu, H. Zhao, J. Chang, Z. Zhang and Y. Zhang (2017). "Gold nanorod-based poly(lactic-co-glycolic acid) with manganese dioxide core-shell structured multifunctional nanoplatform for cancer theranostic applications." Int J Nanomedicine 12: 3059-3075. Yan, C., C. Chen, L. Hou, H. Zhang, Y. Che, Y. Qi, X. Zhang, J. Cheng and Z. Zhang (2017). "Single-walled carbon nanotube-loaded doxorubicin and Gd-DTPA for targeted drug delivery and magnetic resonance imaging." J Drug Target 25(2): 163-171. Zhang, H., H. Zhang, X. Zhu, X. Zhang, Q. Chen, J. Chen, L. Hou and Z. Zhang (2017). "Visible-light-sensitive titanium dioxide nanoplatform for tumor-responsive Fe2+ liberating and artemisinin delivery." Oncotarget. Zhu, X., H. Huang, Y. Zhang, H. Zhang, L. Hou and Z. Zhang (2017). "Cit/CuS@Fe3O4-based and enzyme-responsive magnetic nanoparticles for tumor chemotherapy, photothermal, and photodynamic therapy." J Biomater Appl 31(7): 1010-1025. Zhu, X., Y. Zhang, H. Huang, H. Zhang, L. Hou and Z. Zhang (2017). "Folic acid-modified and functionalized CuS nanocrystal-based nanoparticles for combined tumor chemo- and photothermal therapy." J Drug Target 25(5): 425-435 Feng, Q., Y. Zhang, W. Zhang, Y. Hao, Y. Wang, H. Zhang, L. Hou and Z. Zhang (2017). "Programmed near-infrared light-responsive drug delivery system for combined magnetic tumor-targeting magnetic resonance imaging and chemo-phototherapy." Acta Biomater 49: 402-413. Feng, Q., Y. Zhang, W. Zhang, X. Shan, Y. Yuan, H. Zhang, L. Hou and Z. Zhang (2016). "Tumor-targeted and multi-stimuli responsive drug delivery system for near-infrared light induced chemo-phototherapy and photoacoustic tomography." Acta Biomater 38: 129-142 Hao, Y., L. Wang, B. Zhang, D. Li, D. Meng, J. Shi, H. Zhang, Z. Zhang and Y. Zhang (2016). "Manganese dioxide nanosheets-based redox/pH-responsive drug delivery system for cancer theranostic application." Int J Nanomedicine 11: 1759-1778 Hao, Y., L. Wang, B. Zhang, H. Zhao, M. Niu, Y. Hu, C. Zheng, H. Zhang, J. Chang, Z. Zhang and Y. Zhang (2016). "Multifunctional nanosheets based on folic acid modified manganese oxide for tumor-targeting theranostic application." Nanotechnology 27(2): 025101 Hou, L., Q. Feng, Y. Wang, X. Yang, J. Ren, Y. Shi, X. Shan, Y. Yuan, Y. Wang and Z. Zhang (2016). "Multifunctional hyaluronic acid modified graphene oxide loaded with mitoxantrone for overcoming drug resistance in cancer." Nanotechnology 27(1): 015701 Hou, L., Y. Shi, G. Jiang, W. Liu, H. Han, Q. Feng, J. Ren, Y. Yuan, Y. Wang, J. Shi and Z. Zhang (2016). "Smart nanocomposite hydrogels based on azo crosslinked graphene oxide for oral colon-specific drug delivery." Nanotechnology 27(31): 315105 Hou, L., X. Yang, J. Ren, Y. Wang, H. Zhang, Q. Feng, Y. Shi, X. Shan, Y. Yuan and Z. Zhang (2016). "A novel redox-sensitive system based on single-walled carbon nanotubes for chemo-photothermal therapy and magnetic resonance imaging." Int J Nanomedicine 11: 607-624 Li, H., Y. Hao, N. Wang, L. Wang, S. Jia, Y. Wang, L. Yang, Y. Zhang and Z. Zhang (2016). "DOTAP functionalizing single-walled carbon nanotubes as non-viral vectors for efficient intracellular siRNA delivery." Drug Deliv 23(3): 840-848 Ren, X., L. Liu, Y. Zhou, Y. Zhu, H. Zhang, Z. Zhang and H. Li (2016). "Nanoparticle siRNA against BMI-1 with a Polyethylenimine-Laminarin Conjugate for Gene Therapy in Human Breast Cancer." Bioconjug Chem 27(1): 66-73 Shi, J., Z. Chen, L. Wang, B. Wang, L. Xu, L. Hou and Z. Zhang (2016). "A tumor-specific cleavable nanosystem of PEG-modified C60@Au hybrid aggregates for radio frequency-controlled release, hyperthermia, photodynamic therapy and X-ray imaging." Acta Biomater 29: 282-297 Shi, J., B. Wang, Z. Chen, W. Liu, J. Pan, L. Hou and Z. Zhang (2016). "A Multi-Functional Tumor Theranostic Nanoplatform for MRI Guided Photothermal-Chemotherapy." Pharm Res 33(6): 1472-1485 Shi, J., B. Wang, L. Wang, T. Lu, Y. Fu, H. Zhang and Z. Zhang (2016). "Fullerene (C60)-based tumor-targeting nanoparticles with "off-on" state for enhanced treatment of cancer." J Control Release 235: 245-258