宋立华 - 北京化工大学 - 生命科学与技术学院

个人简介

教育背景： 2001.8-2006.6 军事医学科学院，博士（军事预防医学专业） 1997.9-2001.7 山东大学生命科学学院，学士（微生物学专业）工作经历： 2010.7-2013.6 美国NIH/NIAID/RML博士后 2009.9-2018.7 军事医学科学院微生物流行病研究所，副研究员 2019.1-至今北京化工大学生命科学与技术学院，见习教授

研究领域

重要病原微生物的防治技术与致病机制。重点关注新发突发病毒病、专性胞内寄生菌和多重耐药菌等。采用生物化学、生物信息学、合成生物学等多学科方法，开展传染病防控新技术新方法研究。目前的主要研究方向有: 1.Q热立克次体培养新方法。 2.沙眼衣原体Pgp4调控基因转录机制。 3.新发病毒病的流行病学分析。

近期论文

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1. Tao Wang, Yonghui Yu, Xiaofei Liang, Shengdong Luo, Zemin He, Zhihui Sun, Yongqiang Jiang, Anders Omsland, Pei Zhou and Lihua Song. Lipid A has significance for optimal growth of Coxiella burnetii in macrophage-like THP-1 cells and to a lesser extent in axenic media and non-phagocytic cells. Frontiers in Cellular and Infection Microbiology, 2018, 8: 192. doi: 10.3389/fcimb.2018.00192 2. 鲁辛辛, 冯乐, 于永慧, 罗声栋, 孙志会, 王涛, 端青, 王宁利, 宋立华. 青海藏区B型沙眼衣原体的分离培养与鉴定. 微生物学通报, 2017, 44(6): 1444-1450. 3. 于永慧, 王涛, 罗声栋, 冯乐, 孙志会, 宋立华. Q热性心内膜炎1例抗I相和II相抗原IgG抗体的跟踪检测报道. 军事医学, 2017, 41(2): 160-161. 4. Le Feng, Xinxin Lu, Yonghui Yu, Tao Wang, Shengdong Luo, Zhihui Sun, Qing, Duan, Ningli Wang, Lihua Song. Survey, Culture, and Genome Analysis of Ocular Chlamydia trachomatis in Tibetan Boarding Primary Schools in Qinghai Province, China. Frontiers in Cellular and Infection Microbiology, 2017, 6: 207. doi: 10.3389/fcimb.2016.00207. 5. Yongfeng Lu, Jun He, Tingting Zuo, Yanwei Li, Hong Zhu, Qing Duan, Lihua Song. Phylogeography of Francisella tularensis from Tibet, China: Evidence for an Asian Origin and Radiation of Holarctica-Type Tularemia. Ticks Tick Borne Dis, 2016, 7(5): 865-868. 6. Chunfu Yang, Tregei Starr, Lihua Song, John H. Carlson, Gail L. Sturdevant, Paul A. Beare, William M. Whitmire, Harlan D. Caldwell. Chlamydial lytic exit from host cells is plasmid regulated. mBio, 2015, 6(6): e01648-15. doi:10.1128/mBio.01648-15. 7. Stephen F. Porcel, John H. Carlson, Daniel E. Sturdevant, Gail L. Sturdevant, Kishore Kanakabandi, Kimmo Virtaneva, Hannah Wilder, William M. Whitmire, Lihua Song, Harlan D. Caldwell. Transcriptional Profiling of Human Epithelial Cells Infected with Plasmid-Bearing and Plasmid-Deficient Chlamydia trachomatis. Infection and Immunity, 2015, 83(2): 534-543. 8. Gail L. Sturdevant, John H. Carlson, William M. Whitmire, Bing Zhou, Lihua Song, and Harlan D. Caldwell. Infectivity of urogenital Chlamydia trachomatis plasmid-deficient, CT135-null, and double-deficient strains in female mice [J]. Pathogens and Disease, 2014, 71(1): 90-92. 9. Lihua Song, John H. Carlson, Bing Zhou, Kimmo Virtaneva, William M. Whitmire, Gail L. Sturdevant, Stephen F. Porcella, Grant McClarty, and Harlan D. Caldwell. Plasmid-mediated transformation tropism of chlamydial biovars [J]. Pathogens and Disease, 2014, 70(2): 189-193. Lihua Song, John H. Carlson, William M. Whitmire, Laszlo Kari, Kimmo Virtaneva, Daniel E. Sturdevant, Heather Watkins, Bing Zhou, Gail L. Sturdevant, Stephen F. Porcella, Grant McClarty, and Harlan D. Caldwell. Chlamydia trachomatis Plasmid-Encoded Pgp4 Is a Transcriptional Regulator of Virulence-Associated Genes [J]. Infection and Immunity, 2013, 81(3): 636-44. (commented)