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个人简介

2017-至今,华南理工大学特聘副研究员 2016-2017,中国科学技术大学,生命科学学院助理研究员 2010-2016,中国科学技术大学,细胞生物学博士 2006-2010,新乡医学院,生物技术专业,学士

研究领域

肿瘤微环境与能量代谢研究

近期论文

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1)Sun, L.C., and Gao, P.* (2017). Small molecules remain on target for c-Myc. Elife 6. e22915 2)Sun, L.C., Song, L.B., Wan, Q.F., Wu, G.W., Li, X.H., Wang, Y.H., Wang, J., Liu, Z.J., Zhong, X.Y., He, X.P., Shen, S. Q., Pan, X., Li, A. L., Wang, Y. L.,Gao, P.*, Tang, H. R.*, Zhang, H. F.* (2015). cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. Cell Research 25, 429-444. 3)Sun, L.C., He, X.P., Cao, Y., Gao, P.*, and Zhang, H.* (2014). MicroRNAs and energy metabolism in cancer cells. In MicroRNAs: Key Regulators of Oncogenesis (Springer), pp. 83-95. 4)Wu, G.W., Yuan, M.Q., Shen, S.Q., Ma, X.Y., Fang, J.W., Zhu, L.B., Sun, L.C., Liu, Z.J., He, X.P., Huang, D., Li, T.T., Li, C.C., Wu, J., Hu, X., Li, Z.Y., Song, L.B., Qu, K., Zhang, H.F.*, Gao, P.* (2017). Menin enhances c-Myc-mediated transcription to promote cancer progression. Nature communications 8 5)Zhong, X.Y., Tian, S.Y., Zhang, X., Diao, X.W., Dong, F.T., Yang, J., Li, Z.Y., Sun, L.C., Wang, L., He, X.P., Wu, G.W., Hu, X., Wang, L.H., Song, L.B., Zhang, H.F., Pan, X., Li, A.L.*, Gao, P.* (2017). CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis. EMBO Rep 18, 809-825. 6)Zhang, M., Zhang, W.J., Wu, Z.S., Liu, S.M., Sun, L.C., Zhong, Y.H., Zhang, X., Kong, X.J., Qian, P.X., Zhang, H.F., Lobie, P.E.*, Zhu, T.* (2016). Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma. Oncotarget 7, 3267-3282. 7)Xiang, Y., Stine, Z. E., Xia, J. S., Lu, Y. Q., O'Connor, R. S., Altman, B. J., Hsieh, A. L., Gouw, A. M., Thomas, A. G., Gao, P., Sun, L. C., Song, L. B., Yan, B., Slusher, B. S., Zhuo, J. L., Ooi, L. L., Lee, C. G. L., Mancuso, A., McCallion, A. S., Le, A., Milone, M. C., Rayport, S., Felsher, D. W., Dang, C. V.* (2015). Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis. Journal of Clinical Investigation 125, 2293-2306. 8)Ma, X.Y., Li, C.C., Sun, L.C., Huang, D., Li, T.T., He, X.P., Wu, G.W., Yang, Z., Zhong, X.Y., Song, L.B., Gao, P.*, Zhang, H.F.* (2014). Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1. Nature communications 5. 9)Huang, D., Li, T. T., Li, X. H., Zhang, L., Sun, L. C., He, X. P., Zhong, X. Y., Jia, D. Y., Song, L. B., Semenza, G. L., Gao, P., Zhang, H.F.* (2014) HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression. Cell reports 8, 1930-1942 10)Gao, P.*, Sun, L.C., He, X.P., Cao, Y., Zhang, H.F. (2012) MicroRNAs and the Warburg Effect: new players in an old arena. Curr Gene Ther, 12(4), 285-291.

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