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Dong-Dong Luo, Kai Peng, Jia-Yu Yang, Pawinee Piyachaturawat, Witchuda Saengsawang, Lei Ao, Wan-Zhou Zhao, Yu Tang*, Sheng-biaoWan*. Structural modification of oridonin via DAST induced rearrangement. RSC Adv. 2018, 8(52): 29548–29554. Chao Yang, Iris L.K. Wong, Kai Peng, Zhen Liu, Peng Wang, Tingfu Jiang, Tao Jiang, Larry M.C. Chow, Sheng-Biao Wan*. Extending the structureactivity relationship study of marine natural ningalin B analogues as P-glycoprotein inhibitors. Eur J Med Chem, 2017, 125, 795−806. Iris L. K. Wong, Bao-Chao Wang, Jian Yuan, Liang-Xing Duan, Zhen Liu, Tao Liu, Xue-Min Li, Xuesen Hu, Xiao-Yu Zhang, Tao Jiang, Sheng-Biao Wan*, and Larry M. C. Chow*. Potent and Nontoxic Chemosensitizer of P-Glycoprotein-mediated Multidrug Resistance in Cancer: Synthesis and Evaluation of Methylated Epigallocatechin, Gallocatechin, and Dihydromyricetin Derivatives. J Med Chem, 2015, 58, 4529−4549. Chiou J., Wan S., Chan K. F., So P. K., He D., Chan E. W., Chan T.H., Wong K.Y., Tao J., Chen S. Ebselen as a potent covalent inhibitor of New Delhi metallo-β-lactamase (NDM-1).ChemCommun, 2015, 51(46), 9543-6. Zhen Wang, Iris L. K. Wong, Fu Xing Li, Chao Yang, Zhen Liu, Tao Jiang, Ting Fu Jiang, Larry M. C. Chow* and Sheng Biao Wan*. Optimization of Permethyl Ningalin B Analogues as P-glycoprotein Inhibitors. Bioorgan Med Chem, 2015, 23, 5566-73. Chao Yang, Iris L. K. Wong, Wen Bin Jin, Tao Jiang, Larry M. C. Chow* and Wan Sheng Biao*. Modification of Marine Natural Product Ningalin B and SAR Study Lead to Potent P-Glycoprotein Inhibitors. Marine Drugs.2014, 12, 209-5221. Jin Wen Bin,Wong Iris L. K., Hu Xue Shen, Zhang Xiao Yu, Li Fu Xing, Jiang Tao,Larry M. C. Chow* andWan Sheng Biao*. Structure-activity relationship study of permethyl ningalin B analogues as P-glycoprotein chemosensitizers. J Med Chem, 2013, 56, 9057-9070. Yuan Jian,Wong Iris L. K., Jiang Tao, Wang Si Wen, Liu Tao, Wen Bin Jin, Larry M. C. Chow* andWan Sheng Biao*. Synthesis of methylated quercetin derivatives and their reversal activities on P-gp- and BCRP-mediated multidrug resistance tumour cells. Eur J Med Chem, 2012, 54, 413-422. Zhang Pu Yong, Wong Iris L. K., Yan,Clare S. W., Zhang Xiao Yu, Jiang Tao,Larry M. C. Chow* and Wan Sheng Biao*. Design and Syntheses of Permethyl Ningalin B Analogues: Potent Multidrug Resistance (MDR) Reversal Agents of Cancer Cells.J Med Chem, 2010, 53(14), 5108-5120. Yang Huan-Jie, Sun Dong-Kui, Chen Di, Cui Qiu-Zhi Cindy, Gu Yan-Yan, Jiang Tao, Chen Wei, Wan Sheng Biao*and Dou Q. Ping*. Antitumor activity of novel fluoro-substituted (-)-epigallocatechin-3-gallate analogs.Cancer Lett, 2010, 292(1), 48-53. Wan Sheng Biao, Yang Huan jie, Zhou Zhong yuan, Cui Qiu zhi Cindy, Chen Di, Kanwar Jyoti, Mohammad Imthiyaz, Dou Q. Ping, Chan Tak Hang*. Evaluation of curcumin acetates and amino acid conjugates as proteasome inhibitors.Int J Mol Med, 2010,26(4), 447-455. Huo, C.; Wan, S. B.; Lam, W. H.; Li, L.; Wang, Z.; Landis-Piwowar, K. R.; Chen, D.; Dou, Q. P.; Chan, T. H. The challenge of developing green tea polyphenols as therapeutic agents. Inflammopharmacology (2008), 16(5), 248-252. Dou, Q. P.; Landis-Piwowar, K. R.; Chen, D.; Huo, C.; Wan, S. B.; Chan, T. H. Green tea polyphenols as a natural tumour cell proteasome inhibitor. Inflammopharmacology (2008), 16(5), 208-212. Yu, Zhiyong; Qin, Xu Long; Gu, Yan Yan; Chen, Di; Cui, Qiuzhi Cindy; Jiang, Tao; Wan, Sheng Biao; Dou, Q. Ping. Prodrugs of fluoro-substituted benzoates of EGC as tumor cellular proteasome inhibitors and apoptosis inducers. International Journal of Molecular Sciences (2008), 9(6), 951-961. Wan, Sheng Biao; Liu, Zhe Lin; Chen, Di; Dou, Qing Ping; Jiang, Tao. Polyphosphorous acid-catalyzed cyclization in the synthesis of cryptolepine derivatives. Chinese Chemical Letters (2007), 18(10), 1179-1181. Landis-Piwowar, Kristin R.; Wan, Sheng Biao; Wiegand, Richard A.; Kuhn, Deborah J.; Chan, Tak Hang; Dou, Q. Ping. Methylation suppresses the proteasome-inhibitory function of green tea polyphenols. Journal of Cellular Physiology (2007), 213(1), 252-260 Wan, Sheng Biao; Chen, Di; Dou, Q. Ping; Chan, Tak Hang. Study of the green tea polyphenols catechin-3-gallate (CG) and epicatechin-3-gallate (ECG) as proteasome inhibitors. Bioorganic & Medicinal Chemistry (2004), 12(13), 3521-3527. Wan, Sheng Biao; Chan, Tak Hang. Enantioselective synthesis of afzelechin and epiafzelechin. Tetrahedron (2004), 60(37), 8207-8211. Wan, Sheng Biao; Landis-Piwowar, Kristin R.; Kuhn, Deborah J.; Chen, Di; Dou, Q. Ping; Chan, Tak Hang. Structure-activity study of epigallocatechin gallate (EGCG) analogs as proteasome inhibitors. Bioorganic & Medicinal Chemistry (2005), 13(6), 2177-2185. Wan, Sheng Biao; Dou, Q. Ping; Chan, Tak Hang. Regiospecific and enantioselective synthesis of methylated metabolites of tea catechins. Tetrahedron (2006), 62(25), 5897-5904.
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