个人简介
Professional Experiences
July 2023-Present, Professor, Department of Chemistry, HKUST
July 2017- June 2023, Associate Professor, Department of Chemistry, HKUST, HK.
08/2011-06/2017, Assistant Professor, Department of Chemistry, HKUST, HK.
06/2008-07/2011, Postdoctoral Fellow (Advisor: Amos B. Smith, III): University of Pennsylvania, USA.
Education Background
2003-2008, Ph.D. (Advisor: Frank E. McDonald): Emory University, USA.
2000-2003, M.S. (Advisor: Can-Cheng Guo): Hunan University, China.
1996-2000, B.S. Hunan University, China.
Honors and Awards
2015, Thieme Chemistry Journal Award
2014, Asian Core Program Lectureship Award (China), Malaysia
2014, Asian Core Program Lectureship Award (Korea), Malaysia
2012, Asian Core Program Lectureship Award (Japan), Singapore.
2008, Charles Lester Award for Outstanding Performance in Chemistry, Emory University
近期论文
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Liyan Song*, Yufei Meng, Tongchao Zhao, Lifang Liu, Xiaohong Pan, Binbin Huang, Hongliang Yao, Ran Lin* and Rongbiao Tong*, Unified and Green Oxidation of Amides and Aldehydes for Hofmann and Curtius Rearrangements. Green Chem. 2023, (under revision).
Liang, L.; Wang, W.; Li; M., Xu, Y.; Lu, Z.; Wei, J.; Tang, B. Z.; Sun*, F.; Tong*, R. Water-Soluble Chlorophyll Protein as Efficient Photosensitizer for Cancer Photodynamic Therapy. 2023, (submitted).
Wai Fung Cheng+, Shiqiang Ma+, Yin Tung Lai, Yuen Tsz Cheung, Kornkamon Akkarasereenon, Yiqin Zhou, and Rongbiao Tong*, Bismuth-Mediated Intramolecular Aza-Prins Cyclization of Aza-Achmatowicz Rearrangement Products and Asymmetric Total Syntheses of Suaveoline and Sarpagine Alkaloids. Angew. Chem. Int. Ed., 2023, 62, e202311671.
Wenjun Wang#, Foqing Ma#, Yuen Tsz Cheung, Guihua Zeng, Yiqin Zhou, Zijing Chen, Lixin Liang, Tuoping Luo*, Rongbiao Tong*, Marine Alkaloid Lepadins E and H Induce Ferroptosis for Cancer Chemotherapy. J. Med. Chem. 2023, 66, 11201-11215. DOI: 10.1021/acs.jmedchem.3c00659.
Liyan Song, Gang Li, Wen Guan, Zhijun Zeng, Yanghui Ou, Jiayu Li, Dengqin He, Xiangxiang Fang, Yali Zhang, Jia-qiang Wu, Rongbiao Tong*, Hongliang Yao*. Design, synthesis, and anti-inflammatory activity study of lansiumamide analogues for treatment of acute lung injury. Biomed. Pharmacother. 2023, 166, 115412. DOI: 10.1016/j.biopha.2023.115412.
Yuchen Wang, Shumin Liang, Michael Le Breton, Qiong Qiong Wang, Qianyun Liu, Chin Hung Ho, Bin Yu Kuang, Cheng Wu, Mattias Hallquist, Rongbiao Tong, Jian Zhen Yu*. Field observations of C2 and C3 organosulfates and insights into their formation mechanisms at a suburban site in Hong Kong. Sci. Total Environ. 2023, 904, 166851.
Wei, W.; Cheung, K. K.; Lin, R.; Kong, L. C.; Chan, K. L.; Sung, H.; Williams*, I.; Tong*, R.; Lin*, Z.; Jia*, G. [2+2+1+1] cycloaddition for de novo synthesis of densely functionalized phenols. Angew. Chem. Int. Ed., 2023, 62, e202307251.
Tao Zheng, Jun Xu,* Shaojun Cheng, Jianghai Ye, Shiqiang Ma,* Rongbiao Tong*, Green Halogenation of Indoles with Oxone-Halide. J. Org. Chem. 2023, 88, 11497-11503. DOI: 10.1021/acs.joc.3c00638.
Rongbiao Tong*, The Untold Journey of Total Synthesis of Natural Products. Synlett, 2023, accepted (invited Account).
Peilin Tian, Rongbiao Tong*, In-water Oxidative Suzuki Coupling of Arenes and Arylboronic Acids Using H2O2 as Terminal Oxidant. Green Chem. 2023, Accepted.
Liyan Song*, Yiqin Zhou, Hanbin Liang, Hongzuo Li, Yunrong Lai, Hongliang Yao, Ran Lin* and Rongbiao Tong*, Two Green Protocols for Halogenative Semipinacol Rearrangement. J. Org. Chem. 2023, 88, 504-512. DOI: 10.1021/acs.joc.2c02496.
Peilin Tian, Wenkang Ye, Xiayan Zhang, Yi Tong, Pei-Yuan Qian*, and Rongbiao Tong*. Ten-step Asymmetric Total Syntheses of Potent Antibiotics Anthracimycin and Anthracimycin B. Chem. Sci. 2022, 13, 12776-12781. DOI: 10.1039/d2sc05049h. Highlighted in Synfacts 2023, 19(01), 0090. DOI: 10.1055/s-0042-1751771.
Yiting Zheng†, Yuen Tsz Cheung#, Lixin Liang†, Huiying Qiu, Lei Zhang, Anson Tsang, Qing Chen* & Rongbiao Tong*, Electrochemical Oxidative Rearrangement of Tetrahydro-β-carbolines in Zero-gap Flow Cell. Chem. Sci. 2022, 13, 10479-10485. DOI: 10.1039/D2SC03951F.
Lixin Liang†, Liandong Guo†, and Rongbiao Tong*, Achmatowicz Rearrangement-inspired Development of Green Chemistry, Organic Methodology, and Total Synthesis of Natural Products. Acc. Chem. Res. 2022, 55. 2326-2340. DOI: 10.1021/acs.accounts.2c00358.
Liyan Song*, Yunrong Lai, Hongzuo Li, Jipeng Ding, Hongliang Yao, Qian Su, Binbin Huang, Ming-An Ouyang, and Rongbiao Tong*, Environmentally Benign and User-friendly in situ Generation of Nitrile Imine from Hydrazone for 1,3-Dipolar Cycloaddition. J. Org. Chem. 2022, 87, 10550-10554. DOI: 10.1021/acs.joc.2c01391.
Xiayan Zhang, Yi Tong, Gang Li, Hao Zhao, Guanye Chen, Hongliang Yao*, Rongbiao Tong*. [1,5]-Allyl Shift by a Sequential Achmatowicz/Oxonia‒Cope/Retro-Achmatowicz Rearrangement. Angew. Chem. Int. Ed. 2022, 61, e202205919. DOI:10.1002/anie.202205919.
Chenxi He, Foqing Ma, Wei Zhang, and Rongbiao Tong,* Reinvestigating FeBr3-Catalyzed Alcohol Oxidation with H2O2: Is High-valent Iron Species (HIS) or Reactive Brominating Species (RBS) Responsible for Alcohol Oxidation? Org. Lett. 2022, 24, 3499-3503. DOI: 10.1021/acs.orglett.2c01133.
Zhao*, G-D.; Wang, Y.; Wang, C.; Lei, H.; Yi, B.; Tong*, R. Fenton-like Chemistry Enables Catalytic Oxidative Desulfurization of Thioacetals and Thioketals with Hydrogen Peroxide. Green Chem. 2022, 24, 4041-4049. DOI: 10.1039/D2GC01050J.
Guo, L.-D.; Xu, Z.; Tong*, R. Asymmetric Total Synthesis of Indole Diterpenes Paspalicine, Paspalinine, and Paspalinine-13-ene. Angew. Chem. Int. Ed. 2021, Accepted. DOI: 10.1002/anie.202115384.
Marquez-Cadena, M. A.; Zhang*, W.; Tong*, R. Synthetic Studies toward the Berkeleyacetal Core Architecture. Org. Lett. 2021, 23, ASAP. DOI: 10.1021/acs.orglett.1c03559.
Liang, L.; Zhou, S.; Zhang*, W.; Tong*, R. Catalytic Asymmetric Alkynylation of 3,4-Dihydro-beta-carbolinium Ions Enables Collective Total Syntheses of Indole Alkaloids. Angew. Chem. Int. Ed. 2021, ASAP. DOI: 10.1002/ange.202112383.
Wang, Y.-C.; Tong*, R.; Yu*, J.-Z. Chemical Synthesis of Multifunctional Air Pollutants: Terpene-derived Nitroxyl Organosulfates. Environ. Sci. Tech. 2021, ASAP. DOI:10.1021/acs.est.1c00348.
Zhao, G.; Wang, E.; Tong*, R. From Reactive Oxygen Species to Reactive Brominating Species: Fenton Chemistry for Oxidative Bromination. ACS Sustain. Chem. Eng., 2021, 9, 6118-6125. DOI: 10.1021/acssuschemeng.1c01709.
Zhao, G.; Liang, L.; Wang, E.; Wang, Y.; Tong*, R. Fenton Chemistry for Achmatowicz rearrangement. ACS Catal. 2021, 11, 3740-3748. DOI:10.1021/acscatal.1c00219.
Zhao, G.; Liang, L.; Wang, E.; Lou, S.; Qi, R.; Tong*, R. Fenton Chemistry Enables Catalytic Oxidative Rearrangement of Indoles using Hydrogen Peroxide. Green Chem. 2021, 23, 2300-2307. DOI: 10.1039/d1gc00297. Selected by editor as a 2021 HOT Green Chemistry Article.
Wang, J.; Márquez-Cadena,† M. A.; Tong*, R. Asymmetric Total Syntheses of (+)-Penostatins A and C. Org. Lett. 2020, 22, 5074-5078. **Highlight in ChemBeanGo 2020-07-06.
Liaw, M. W.; Cheng, W. F.; Tong*, R. C-Aryl Glycosylation: Palladium-catalyzed Aryl-Allyl Coupling of Achmatowicz Rearrangement Products with Arylboronic Acids. J. Org. Chem. 2020, 85, 6663-6674. ** Highlighted in Organic Chemistry Portal (ID: J42-Y2020).
Song*, L.; Su, Q.; Lin, X.; Du, Z.; Xu, H.; Ouyang, M.-A.; Yao, H.; Tong*, R. Cascade Claisen and Meinwald Rearrangement for One-Pot Divergent Synthesis of Benzofurans and 2H-Chromenes. Org. Lett. 2020, 22, 3004-3009. DOI: 10.1021/acs.orglett.0c00770.
Zhao, G.; Canterbury, D. P.; Taylor, A. P.; Cheng, X.; Mikochik, P.; Bagley, S. W.; Tong*, R. Synthesis of 2-Arylpiperidines via Pd-Catalyzed Arylation of Aza-Achmatowicz Rearrangement Products with Arylboronic Acids. Org. Lett. 2020, 22, 458-463. DOI: 10.1021/acs.orglett.9b04220. **Highlighted in Synfacts 2020, 16(4), 0383. Highlighted in Organic Chemistry Portal (ID: J54-Y2020).
Márquez-Cadena,† M. A.; Ren,† J.; Ye, W.; Qian*, P.; Tong*, R. Asymmetric Total Synthesis Enables Discovery of Antibacterial Activity of Siladenoserinols A and H. Org. Lett. 2019, 21, ASAP. DOI: 10.1021/acs.orglett.9b03857. (†equal contribution).
Xu#, J.; Liang#, L.; Zheng, H.; Chi, Y. R.; Tong*, R. Green Oxidation of Indoles using Halide Catalysis. Nat. Commun., 2019, 10: 4754. DOI: https://doi.org/10.1038/s41467-019-12768-4. (#equal contribution).
Wang, Y.-C.; Ma, Y.; Li, X.; Kuang, B. Y.; Huang, C.; Tong*, R; Yu*, J. Z. Monoterpene and sesquiterpene α-hydroxy organosulfates: Synthesis, MS/MS characteristics, and ambient presence. Environ. Sci. Tech. 2019, 53, 12278-12290. DOI: 10.1021/acs.est.9b04703.
Zhang, Z.; Zhang, W.; Kang, F.; Ip, F. C. F.; Ip*, N. Y.; Tong*, R. Asymmetric Total Syntheses of Rhynchophylline and Isorhynchophylline. J. Org. Chem. 2019, 84, 11359-11365. DOI: 10.1021/acs.joc.9b01977.
Zhao, G.; Liang, L.; Wen, C. H. E.; Tong*, R. Efficient in situ Generation of Nitrile Oxides from NaCl-Oxone Oxidation of Various Aldoximes and their 1,3-Dipolar Cycloaddition. Org. Lett., 2019, 21, 315-319. DOI: 10.1021/acs.orglett.8b03829.
Zhao, G.; Tong*, R. Silica gel enables Achmatowicz rearrangement using KBr/Oxone under “anhydrous” condition for one-pot functionalization. Tetrahedron, 2019, 75, 1669-1675. DOI: 10.1016/j.tet.2018.12.022. (Invited contribution)
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