陈令新 - 中国科学院烟台海岸带研究所 -

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陈令新研究员博导收藏完善纠错
中国科学院烟台海岸带研究所
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个人简介

2003年毕业于中国科学院大连化学物理研究所获分析化学博士学位。2004年1月至2009年6月分别在清华大学化学系，韩国汉阳大学应用化学系从事博士后、研究员合作研究。2008年12月到中国科学院烟台海岸带可持续发展研究所工作。主要研究领域：海岸带环境特征污染物检测仪器、方法与技术；微纳化学/生物传感器；微流控芯片技术。以主要完成人身份参加的国家自然基金等项目10余项。现主持山东省重点科技项目等相关课题研究。已在国内外刊物上发表论文70余篇，其中SCI收录论文40余篇。申请中国发明专利15项，其中10项获得授权。著、编学术著作2部。专利 [1] 李博伟,陈令新,齐骥,等. 一种基于离子印迹包被量子点检测液体样品的微流控纸芯片及其制备方法. 2016-12-26. [2] 陈令新,王巧宁,付龙文,等. 一种开放海域沉积物污染的修复方法. 2016-11-24. [3] 王巧宁,陈令新,付龙文,等. 一种沙福芽孢杆菌及在修复开放海域污染物中的应用. 2016-11-24. [4] 陈兆鹏,张耀文,陈令新,等. 一种锰离子比色法检测试剂盒及其检测方法. 2016-11-22. [5] 付龙文,温国义,王巧宁,等. 海洋环境生态修复水下观测机器人. 2016-05-06. [6] 温国义,宋文鹏,付龙文,等. 拖曳式自主深度水下观测系统. 2016-05-06. [7] 于法标,陈令新,高敏,等. 用于测定多硫化半胱氨酸氟硼吡咯类荧光团衍生物及其应用. 2015-07-23. [8] 陈令新,于法标,黄严,等. 用于测定超氧阴离子和多硫化氢的荧光团衍生物及其应用. 2015-07-23. [9] 陈令新,韩潇玥,于法标. 一种荧光团衍生物及其应用. 2015-05-28. [10] 陈令新,殷堃,柴百惠,等. 一种利用生物元件检测痕量二价铜离子的方法. 2015-05-26. [11] 陈令新,殷堃,于法标,等. 一种基于花菁的探针用于检测痕量二价铜离子的方法. 2015-05-26. [12] 陈令新,张忠,李博伟. 一种基于量子点的蛋白质印迹纸芯片的制备方法. 2015-04-23. [13] 冯巍巍,蔡宗岐,马正,等. 一种基于复合光谱测量的在线水质监测装置. 2014-09-15. [14] 李金花,陈令新,董瑞晨. 一种制备雌二醇分子印迹磁性微球的方法. 2014-07-22. [15] 陈令新,张忠,李金花. 一种管状蛋白质印迹催化磁性微马达及其制备和应用. 2014-07-22. [16] 李金花,董瑞晨,陈令新. 一种温敏双酚a印迹聚合物微球及其应用. 2014-07-22. [17] 陈令新,张忠,李金花. 一种汞离子印迹聚合物及其方法和应用. 2014-07-22. [18] 陈令新,张忠,李金花. 一种基于量子点的蛋白质核壳印迹微球的制备方法. 2014-07-22. [19] 陈令新,殷堃,于法标,等. 基于花青的有机化合物及其应用. 2014-07-08. [20] 陈令新,殷堃,于法标,等. 一种基于花青的有机化合物及其应用. 2014-06-25. [21] 于法标,陈令新,陈浩,等. 一种花菁类化合物及其应用. 2014-04-28. [22] 于法标,陈令新,高敏,等. 一种氟硼吡咯类衍生荧光化合物及其应用. 2014-04-28. [23] 于法标,陈令新,景晓彤,等. 一种氟硼吡咯类化合物及其应用. 2014-01-23. [24] 李金花,陈令新,蔡晓强,等. 一种利用双功能单体协同作用制备铅离子印迹聚合物微球的方法. 2013-12-30. [25] 陈令新,孙西艳,付文龙,等. 全自动铜锌铬镉离子在线富集及分析系统. 2013-11-21. [26] 陈令新,殷堃,张卫卫. 一种简便快速检测l-半胱氨酸的方法. 2013-07-23. [27] 陈令新,殷堃,张卫卫. 一种快速检测痕量cu2+的方法. 2013-07-23. [28] 陈令新,张忠,李金花. 荧光蛋白印迹磁性复合微球的制备方法. 2013-07-10. [29] 张卫卫,陈令新,殷堃. 一种快速高效吸附汞离子的载体及其细菌表面展示工程菌和应用. 2013-07-02. [30] 张卫卫,陈令新,王巧宁. 可清除水环境中氨氮的奇异变形杆菌及其应用. 2013-07-02. [31] 陈兆鹏,张志阳,陈令新. 一种钴离子比色法检测试剂盒及其检测方法. 2013-05-15. [32] 陈兆鹏,张志阳,陈令新. 灵敏的现场比色检测空气中的硫化氢试剂盒及其检测方法. 2013-05-15. [33] 陈兆鹏,张志阳,陈令新. 一种铜离子比色法检测试剂盒及其检测方法. 2013-05-15. [34] 付龙文,孙西艳,陈令新,等. 一种纯数字化光电检测系统. 2013-05-08. [35] 付龙文,孙西艳,陈令新,等. 一种纯数字化光电检测系统及其检测方法. 2013-05-08. [36] 李博伟,陈令新,付龙文. 一种便携式纸基微流控芯片色彩检测装置和方法. 2012-12-27. [37] 陈令新,吕颖,孙西艳,等. 小型顺序注射亚硝酸盐分析系统. 2012-11-21. [38] 陈令新,孙西燕,付龙文,等. 水质六价铬全自动快速测量系统. 2012-11-21. [39] 陈令新,孙西燕,付龙文,等. 水质六价铬全自动快速测量系统及其测量方法. 2012-11-21. [40] 赵君才,张文秀,陈令新,等. 一种水体环境多参数在线监测系统. 2012-10-08. [41] 陈令新,于法标,王锐,等. 基于硝基还原检测细胞内硫化氢的荧光探针及其应用. 2012-09-18. [42] 冯巍巍,陈令新,赵广立,等. 一种探头式水体石油污染物在线监测系统与方法. 2012-08-09. [43] 陈令新,张卫卫,牛宗亮,等. 一种能够降解石油的醋酸钙不动杆菌的应用. 2011-10-28. [44] 陈令新,张卫卫,牛宗亮,等. 一种检测奇异变形杆菌的特异的核酸标识序列及其应用. 2011-09-23. [45] 张卫卫,陈令新,牛宗亮,等. 可代谢己烯雌酚的假单胞菌及其应用. 2011-08-05. [46] 陈令新,张卫卫,殷堃,等. 一种能够分泌荧光铁载体的铜绿假单胞菌及其应用. 2011-08-05. [47] 冯巍巍,陈令新,马正. 一种荧光溶解氧在线测量装置. 2011-07-25. [48] 冯巍巍,陈令新,马正. 一种荧光溶解氧在线测量装置及用其检测溶解氧的方法. 2011-07-25. [49] 陈令新,张卫卫,牛宗亮,等. 可代谢呋喃唑酮的乙酸钙不动杆菌及其应用. 2011-02-25. [50] 陈令新,于春伟,张军. 一种萘酰亚胺修饰的罗丹明类衍生物nrc及其制备和应用. 2010-12-24.

研究领域

海岸带环境特征污染物检测仪器、方法与技术微纳化学/生物传感器微流控芯片技术

近期论文

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[1] Arabi, Maryam.,Ostovan, Abbas.,Bagheri, Ahmad Reza.,Guo, Xiaotong.,Li, Jinhua.,...&Chen, Lingxin.(2020).Hydrophilic molecularly imprinted nanospheres for the extraction of rhodamine B followed by HPLC analysis: A green approach and hazardous waste elimination.TALANTA,215,120933. [2] Li, Chuyao.,Yang, Qian.,Wang, Xiaoyan.,Arabi, Maryam.,Peng, Hailong.,...&Chen, Lingxin.(2020).Facile approach to the synthesis of molecularly imprinted ratiometric fluorescence nanosensor for the visual detection of folic acid.FOOD CHEMISTRY,319,126575. [3] Wu, Gege.,Ma, Jiping.,Wang, Shasha.,Chai, Huining.,Guo, Liang.,...&Chen, Lingxin.(2020).Cationic metal-organic framework based mixed-matrix membrane for extraction of phenoxy carboxylic acid (PCA) herbicides from water samples followed by UHPLC-MS/MS determination.JOURNAL OF HAZARDOUS MATERIALS,394,122556. [4] Yang, Shixuan.,Ma, Suya.,Zhu, Kongli.,Wang, Minglin.,Li, Jinhua.,...&Chen, Lingxin.(2020).Simultaneous enrichment/determination of six sulfonamides in animal husbandry products and environmental waters by pressure-assisted electrokinetic injection coupled with capillary zone electrophoresis.JOURNAL OF FOOD COMPOSITION AND ANALYSIS,88,103462. [5] Wang, Yue,Zhang, Li,Huang, Yan,Wang, Xiaoyan,Zhang, Liangwei,&Chen, Lingxin.(2020).Rational design of a nitroreductase-activatable two-photon fluorescent probe for hypoxia imaging in cell and in vivo.SENSORS AND ACTUATORS B-CHEMICAL,310,127755. [6] Wang, Xiaoyan.,Yu, Shuangmei.,Wang, Jiangru.,Yu, Jialuo.,Arabi, Maryam.,...&Chen, Lingxin.(2020).Fluorescent nanosensor designing via hybrid of carbon dots and post- imprinted polymers for the detection of ovalbumin.TALANTA,211,120727. [7] Wen, Jiahui.,Liu, Yongming.,Li, Jingwen.,Lin, Hao.,Zheng, Yiran.,...&Chen, Lingxin.(2020).A label-free protamine-assisted colorimetric sensor for highly sensitive detection of S1 nuclease activity.ANALYST,145(7),2774-2778. [8] Guo, Xiaotong,Li, Jinhua,Arabi, Maryam,Wang, Xiaoyan,Wang, Yunqing,&Chen, Lingxin.(2020).Molecular-Imprinting-Based Surface-Enhanced Raman Scattering Sensors.ACS SENSORS,5(3),601-619. [9] Yang, Qian.,Li, Chuyao.,Li, Jinhua.,Wang, Xiaoyan.,Arabi, Maryam.,...&Chen, Lingxin.(2020).Rational construction of a triple emission molecular imprinting sensor for accurate naked-eye detection of folic acid.NANOSCALE,12(11),6529-6536. [10] Gao, XQ.,Zhuang, XM.,Tian, CY.,Liu, HT.,Lai, WF.,...&Rogach, AL.(2020).A copper nanocluster incorporated nanogel: Confinement-assisted emission enhancement for zinc ion detection in living cells.SENSORS AND ACTUATORS B-CHEMICAL,307,127626. [11] Ma, Suya.,Yang, Shixuan.,Song, Zhihua.,Li, Jinhua.,Shi, Qiaocui.,...&Chen, Lingxin.(2020).A twin enrichment method based on dispersive liquid-liquid microextraction and field-amplified sample injection for the simultaneous determination of sulfonamides.ANALYST,145(5),1825-1832. [12] Luan, Feng.,Wang, Yunfei.,Zhang, Shuang.,Zhuang, Xuming.,Tian, Chunyuan.,...&Chen, Lingxin.(2020).Facile synthesis of a cyclodextrin-metal organic framework decorated with Ketjen Black and platinum nanoparticles and its application in the electrochemical detection of ofloxacin.ANALYST,145(5),1943-1949. [13] 马昕,郝帼英,张忠,等. 环境友好型比率荧光微流控纸芯片快速检测苯醚甲环唑[J]. 中国科学:化学,2020,50(03):393-405. [14] Wang, Y,Han, XY,Zhang, X,Zhang, L,&Chen, LX.(2020).A high-selectivity fluorescent probe for hypoxia imaging in cells and a tumor-bearing mouse model.ANALYST,145(4),1389-1395. [15] Zhou, JR.,Li, BW.,Qi, AJ.,Shi, YJ.,Qi, J.,...&Chen, LX.(2020).ZnSe quantum dot based ion imprinting technology for fluorescence detecting cadmium and lead ions on a three-dimensional rotary paper-based microfluidic chip.SENSORS AND ACTUATORS B-CHEMICAL,305,127462. [16] Song, ZH.,Li, SH.,Guan, YF.,Wang, S.,Wang, YH.,...&Chen, LX.(2020).Facile synthesis of zirconia-coated mesoporous silica particles by hydrothermal strategy under low potential of hydrogen conditions and functionalization with dodecylphosphonic acid for high-performance liquid chromatography.JOURNAL OF CHROMATOGRAPHY A,1612,460659. [17] Wang, Yue.,Wang, Xiaoyan.,Zhang, Li.,Huang, Yan.,Bi, Liyan.,...&Chen, Lingxin.(2020).A ratiometric fluorescent probe for detecting the endogenous biological signaling molecule superoxide anion and bioimaging during tumor treatment.JOURNAL OF MATERIALS CHEMISTRY B,8(5),1017-1025. [18] Wu, Y,Choi, N,Chen, H,Dang, H,Chen, LX,&Choo, J.(2020).Performance Evaluation of Surface-Enhanced Raman Scattering-Polymerase Chain Reaction Sensors for Future Use in Sensitive Genetic Assays.ANALYTICAL CHEMISTRY,92(3),2628-2634. [19] Liu, Ping.,Li, Bowei.,Fu, Longwen.,Huang, Yan.,Man, Mingsan.,...&Chen, Lingxin.(2020).Hybrid Three Dimensionally Printed Paper-Based Microfluidic Platform for Investigating a Cell's Apoptosis and Intracellular Cross-Talk.ACS SENSORS,5(2),464-473. [20] Lv, M.,Luan, XL.,Guo, XT.,Liao, CY.,Guo, DF.,...&Chen, LX.(2020).A national-scale characterization of organochlorine pesticides (OCPs) in intertidal sediment of China: Occurrence, fate and influential factors.ENVIRONMENTAL POLLUTION,257,113634. [21] Wang, Y,Zhang, LW,&Chen, LX.(2020).Glutathione Peroxidase-Activatable Two-Photon Ratiometric Fluorescent Probe for Redox Mechanism Research in Aging and Mercury Exposure Mice Models.ANALYTICAL CHEMISTRY,92(2),1997-2004. [22] Mei, RC,Wang, YQ,Yu, Q,Yin, YC,Zhao, RF,&Chen, LX.(2020).Gold Nanorod Array-Bridged Internal-Standard SERS Tags: From Ultrasensitivity to Multifunctionality.ACS APPLIED MATERIALS & INTERFACES,12(2),2059-2066. [23] Lin, D.,Li, BW.,Qi, J.,Ji, XF.,Yang, SX.,...&Chen, LX.(2020).Low cost fabrication of microfluidic paper-based analytical devices with water-based polyurethane acrylate and their application for bacterial detection.SENSORS AND ACTUATORS B-CHEMICAL,303,127213. [24] 宋志花,李盛红,杨刚强,等. 人参皂苷类化合物样品前处理及分析检测[J]. 化学进展,2020,32(2/3):239-248. [25] Yang, Q.,Wang, XY.,Peng, HL.,Arabi, M.,Li, JH.,...&Chen, LX.(2020).Ratiometric fluorescence and colorimetry dual-mode assay based on manganese dioxide nanosheets for visual detection of alkaline phosphatase activity.SENSORS AND ACTUATORS B-CHEMICAL,302,127176. [26] 王莉燕,王加男,李金花,等. 分子印迹聚合物在抗生素残留测定中的应用[J]. 色谱,2020,38(3):265-277. [27] 吕敏,陈令新. 近海环境中抗生素分析样品前处理技术的研究进展[J]. 色谱,2020,38(1):95-103. [28] 栾晓琳,乔田峰,吕敏,等. 近百年来大辽河口潮间带中滴滴涕(DDTs)的沉积记录及其对人类活动的响应[J]. 环境化学,2020,39(1):119-127. [29] Wang, Y,Gao, M,Liao, CY,Yu, FB,&Chen, LX.(2019).A sulfydryl-based near-infrared ratiometic fluorescent probe for assessment of acute/chronic mercury exposure via associated determination of superoxide anion and mercury ion in cells and in vivo.SENSORS AND ACTUATORS B-CHEMICAL,301,127038. [30] Huang, Y.,He, N.,Kang, Q.,Shen, DZ.,Wang, XY.,...&Chen, LX.(2019).A carbon dot-based fluorescent nanoprobe for the associated detection of iron ions and the determination of the fluctuation of ascorbic acid induced by hypoxia in cells and in vivo.ANALYST,144(22),6609-6616. [31] Tian, CY,Wang, L,Luan, F,Fu, XL,Zhuang, XM,&Chen, LX.(2019).A novel electrochemiluminescent emitter of europium hydroxide nanorods and its application in bioanalysis.CHEMICAL COMMUNICATIONS,55(83),12479-12482. [32] Ma, JP.,Li, S.,Wu, GG.,Wang, SS.,Guo, XT.,...&Chen, LX.(2019).Preparation of mixed-matrix membranes from metal organic framework (MIL-53) and poly (vinylidene fluoride) for use in determination of sulfonylurea herbicides in aqueous environments by high performance liquid chromatography.JOURNAL OF COLLOID AND INTERFACE SCIENCE,553,834-844. [33] Qi, J.,Li, BW.,Zhou, N.,Wang, XY.,Deng, DM.,...&Chen, LX.(2019).The strategy of antibody-free biomarker analysis by in-situ synthesized molecularly imprinted polymers on movable valve paper-based device.BIOSENSORS & BIOELECTRONICS,142,UNSP 111533. [34] Fu, XL.,Wen, JH.,Li, JW.,Lin, H.,Liu, YM.,...&Chen, LX.(2019).Highly sensitive detection of prostate cancer specific PCA3 mimic DNA using SERS-based competitive lateral flow assay.NANOSCALE,11(33),15530-15536. [35] Huang, Y.,Liu, QL.,Wang, YQ.,He, N.,Zhao, RF.,...&Chen, LX.(2019).Gold nanorods functionalized by a glutathione response near- infrared fluorescent probe as a promising nanoplatform for fluorescence imaging guided precision therapy.NANOSCALE,11(25),12220-12229. [36] Ma, SY.,Gao, FF.,Lu, WH.,Zhou, N.,You, HY.,...&Chen, LX.(2019).Dispersive liquid-liquid microextraction coupled with pressure-assisted electrokinetic injection for simultaneous enrichment of seven phenolic compounds in water samples followed by determination using capillary electrophoresis.JOURNAL OF SEPARATION SCIENCE,42(13),2263-2271. [37] Zhang, S.,Zhuang, XM.,Chen, DD.,Luan, F.,He, T.,...&Chen, LX.(2019).Simultaneous voltammetric determination of guanine and adenine using MnO2 nanosheets and ionic liquid-functionalized graphene combined with a permeation-selective polydopamine membrane.MICROCHIMICA ACTA,186(7),UNSP 450. [38] Gao, M.,Zhang, X.,Wang, Y.,Liu, QL.,Yu, FB.,...&Chen, LX.(2019).Sequential Detection of Superoxide Anion and Hydrogen Polysulfides under Hypoxic Stress via a Spectral-Response-Separated Fluorescent Probe Functioned with a Nitrobenzene Derivative.ANALYTICAL CHEMISTRY,91(12),7774-7781. [39] Wang, Y,Zhang, LW,Zhang, SZ,Liu, Z,&Chen, LX.(2019).High Spatiotemporal Resolution Observation of Glutathione Hydropersulfides in Living Cells and Tissue via a Two-Photon Ratiometric Fluorescent Probe.ANALYTICAL CHEMISTRY,91(12),7812-7818. [40] Yang, Q,Li, JH,Wang, XY,Xiong, H,&Chen, LX.(2019).Ternary Emission of a Blue-, Green-, and Red-Based Molecular Imprinting Fluorescence Sensor for the Multiplexed and Visual Detection of Bovine Hemoglobin.ANALYTICAL CHEMISTRY,91(10),6561-6568. [41] Xu, RF,Wang, Y,You, HY,Zhang, LW,Wang, YQ,&Chen, LX.(2019).A near-infrared fluorescent probe for evaluating endogenous hydrogen peroxide during ischemia/reperfusion injury.ANALYST,144(8),2556-2564. [42] Huang, Y.,He, N.,Wang, YD.,Zhang, LW.,Kang, Q.,...&Chen, LX.(2019).Detection of hypochlorous acid fluctuation via a selective near-infrared fluorescent probe in living cells and in vivo under hypoxic stress.JOURNAL OF MATERIALS CHEMISTRY B,7(15),2557-2564. [43] Yu, Q,Wang, YQ,Mei, RC,Yin, YC,You, JM,&Chen, LX.(2019).Polystyrene Encapsulated SERS Tags as Promising Standard Tools: Simple and Universal in Synthesis; Highly Sensitive and Ultrastable for Bioimaging.ANALYTICAL CHEMISTRY,91(8),5270-5277. [44] He, N.,Bai, S.,Huang, Y.,Xing, YL.,Chen, LX.,...&Lv, CJ.(2019).Evaluation of Glutathione S-Transferase Inhibition Effects on Idiopathic Pulmonary Fibrosis Therapy with a Near-Infrared Fluorescent Probe in Cell and Mice Models.ANALYTICAL CHEMISTRY,91(8),5424-5432. 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