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个人简介

1984年 毕业于华西医科大学药学院,药物化学本科 1997年 毕业于华西医科大学药学院,获硕士学位 2008年 毕业于四川大学华西药学院,获博士学位 1984年~至今 四川大学华西药学院中心测试室任助教、讲师、副教授、研究员(教授) 1991年 西藏自治区卫生学校自愿援藏教师

研究领域

1. 药物“定量保留-活性关系”预测模型及细胞色谱研究 2. 药动学及药物代谢产物研究 3. NIR&Raman在线测定系统方法学及应用研究 4. 中药、中药材及化学药质量标准研究

近期论文

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1.Shurong Wang, Yu Cheng, Zhaoxia Gao, Meijin Xiong, Zhirong Zhang, Liming Ye*. Gas chromatographic-mass spectrometric analysis of d-limonene in human plasma. Journal of Pharmaceutical and Biomedical Analysis. 2007, 44: 1095 - 1099 2.Qiang Zheng, Liming Ye, Rong Gao, Jing Han, Meijin Xiong, Dong Zhao, Tao Gong.Kinetic release of triptolide after injection of renal-targeting 14-succinyl triptolide-lysozyme in a rat kidney study by liquid chromatography / mass spectrometry. Biomedical Chromatography. 2007, 21: 724–729. 3.Shu-Rong Wang, Yu Chen, Li-Ping Wu, Wen-Juan Miao, Mei-Jin Xiong, Cong Chen, Zhi-Rong Zhong and Li-Ming Ye*. Development of predictive quantitative retention-activity relationship models of HMG-CoA reductase inhibitors by biopartitioning micellar chromatography. Journal of Pharmaceutical and Biomedical Analysis. 2008, (2): 243-249 4.Li-Ping Wu, Yu Chen, Shu-Rong Wang, Cong Chen, Li-Ming Ye*. Quantitative retention-activity relationship models for quinolones using biopartitioning micellar chromatography. Biomedical Chromatography. 2008, 22(1):106-114 5.Li-ping Wu, Li-ming Ye, Cong Chen, Jia-qi Wu, Yu Chen. Biopartitioning micellar chromatography separation methods: modelling quantitative retention-activity relationships of cephalosporins. Biomedical Chromatography. 2008, 22: 606-615. 6.Li-ping Wu, Yan Cui, Mei-jin Xiong, Shu-rong Wang, Cong Chen and Li-ming Ye *. Mixed micellar chromatography methods: modelling quantitative retention–activity relationships of angiotensin converting enzyme inhibitors. Biomedical Chromatography. 2008, 22(11):1243-1251 7.Ke Lan, Xuehua Jiang, Yunxia Li, Ling Wang, Jing Zhou, Qian Jiang and Limin Ye. Quantitative determination of rosuvastatin in human plasma by ion pair liquid–liquid extraction using liquid chromatography with electrospray ionization tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 2007, 44: 540-546. 8. Shu-Rong Wang, Cong Chen, Mei-Jin Xiong, Li-Ping Wu, Li-Ming Ye*, Cong Chen. Quantitative retention-activity relationship models of angiotensin enzyme inhibitors using biopartitioning micellar chromatography. Journal of Chromatographic Science. 2010, 48 (2): 134-138 9. Yu Chen, Li-Ping Wu, Li-Ming Ye* Cong Chen. Development of predictive quantitative retention-activity relationship models of alkaloids by mixed micellar liquid chromatography. Biomedical Chromatography. 2010, 24(2):195-201 10.Yan Cui , HaiLinYin , Xu Bao , MeiJin Xiong , Cong Chen and LiMing Ye *. Determination of penehyclidine hydrochloride in beagle dog plasma by liquid chromatography electro spray ionization mass spectrometry and the pharmacokinetic study. Journal of Chinese Pharmaceutical Sciences. 2008, 17:32-38 11.Jian Zhong Wang*, Li Ming Ye, Xiao Bing Chen. A new C27-steroidal glycoside from Ophiogon japonicus. Chinese Chemical Letters. 2008, 19 (1): 82-84 12. Zhang Z, Sun W, Luo P, Wu L, Ye L, Zhang H. Simultaneous determination of five main active constituents of Erigeron multiradiatus by HPLC-DAD-MS. Journal of Pharmaceutical and Biomedical Analysis. 2008, 48 (3): 980-985. 13. Xiao-Juan Ren , Shu-Rong Wang, Yu-Jie Liu, Li-Ping Wu, Cong Chen,Li-Ming Ye*. Effect of acidity of drugs on the prediction for human oral absorption by biopartitioning micellar chromatography. AJXJU(Academic Journal of Xi’an Jiaotong University).2010.229(4):233~240 14. Jintao Xue , Chunjie Wu, Leilei Wang, Su Jiang , Guo Huang , Jiliang Zhang , Silan Wen, Liming Ye*.Dynamic prediction models for alkaloid content using NIR technology for the 4 study and online analysis of parching in Areca Seed. Food Chemistry.2011 (126): 725~730 15. Si-Lan Wen*, Yu-Jie Liu*, Hai-Lin Yin , Liu Zhang*, Jin Xiao, Hong-Yuan Zhu , Jin-Tao Xue* and Li-Ming Ye*.Effect of Acupuncture on Rats with Acute Gouty Arthritis Inflammation: A Metabonomic Method for Profiling of both Urine and Plasma Metabolic Perturbation. AJCM(The American Journal of Chinese Medicine). 2011.39 (2) : 287~300 16. Intra-herb pharmacokinetics interaction between quercetin and isorhamentinLan, K., He, J.-L., ian, Y., Tan, F., Jiang, X.-H., Wang, L., Ye, L.-M. Acta Pharmacologica Sinica, 2008 (29)11:1376 - 1382 17. Jintao Xue , Chunjie Wu, Leilei Wang, Su Jiang , Guo Huang , Jiliang Zhang , Silan Wen, Liming Ye*.Rapid and Automated Analytical Method for Identification of the Types of Parched Areca Seed by Near Infrared Spectroscopy. Asian Journal of Chemistry; 2011 (22) 12:6543

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