个人简介

教育经历 1980-1984 理学学士，华西医科大学药学院 1984-1987 理学硕士，华西医科大学药学院 1987-1989 讲师，华西医科大学药学 1989-1990 中科院上海有机所进修 1991-1994 理学博士，华西医科大学药学院 1995-1997 博士后研究，比利时根特大学 工作经历 1998-1999 副教授 华西医科大学药学院 2000- 教授 四川大学华西药学院 2001-2010 副院长 四川大学华西药学院 2010-2012 四川大学华西药业股份有限公司总经理

研究领域

1. 主动靶向药物研究 2. 手性药物合成研究

1. 主动靶向药物研究 2. 手性药物合成研究

近期论文

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1.Cheng X.; Li W. J.; Nie R. F.; Ma X. J.; Sang R.; Guo L.; Wu Y.* Ligand-Free C–C Coupling Reactions Promoted by Hexagonal Boron Nitride-Supported Palladium(II) Catalyst in Water Adv. Synth. Catal., 2017, 359, 454. 2.Li J.; Yu X. L.; Cossy J.; Lv S. Y.; Zhang H. L.; Su F.; Mykhailiuk P. K.; Wu Y.* Synthesis of CF2H-Substituted Pyrazolines by [3+2] Cycloaddition between CF2HCHN2 and Electron-Deficient Alkenes Eur. J. Org. Chem., 2017, 266. 3.Nie R. F.; Sang, R.; Ma X. J.; Zheng Y.; Cheng X.; Li, W. J.; Guo, L.; Jin H.; Wu Y.* Copper-gamma-cyclodextrin complexes immobilized on hexagonal boron nitride as an efficient catalyst in the multicomponent synthesis of 1,2,3-triazoles Journal of Catalysis, 2016, 344, 286. 4.Wang Y. L.; Cheng X.; Zhan Z.; Ma X. J.; Nie R. F.; Hai L.; Wu Y.* IBX-promoted domino reaction of alpha-hydroxy amides: a facile one-pot synthesis of isatins RSC Adv., 2016, 6, 2870. 5.Wang X. Y.; Zhang C.; Li, J.; Jiang C.; Su F.; Zhan Z.; Hai L.; Chen Z. H.; Wu Y.* Ruthenium-catalyzed 1,2,3-triazole directed intermolecular C-H amidation of arenes with sulfonyl azides RSC Adv., 2016, 6, 68929. 6.Zhan Z.; Cheng X.; Zheng Y.; Ma X. J.; Wang X. Y.; Hai L.; Wu Y.* PhI(OAc)2-promoted metal-free oxidation of 2-oxoaldehydes: a facile one-pot synthesis of cyanoformamides RSC Adv., 2015, 5, 82800. 7.Li J.; Zheng Y.; Yu X. L.; Lv S.Y.; Wang Q. T.; Hai L.; Wu Y.* Synthesis of isatins by the palladium-catalyzed intramolecular acylation of unactivated aryl C(sp(2))-H bonds RSC Adv., 2015, 5, 103280. 8.Qu B. Y.; Li X. C.; Guan M.; Li X.; Hai L.; Wu Y.* Design, synthesis and biological evaluation of multivalent glucosides with high affinity as ligands for brain targeting liposomes Eur. J. Med. Chem., 2014, 72, 110. 9.Zhao Y.; Qu B. Y.; Wu X. Y.; Li X. C.; Liu Q. Q.; Jin X. X.; Guo L.; Hai L.; Wu Y.* Design, synthesis and biological evaluation of brain targeting l-ascorbic acid prodrugs of ibuprofen with “lock-in” function Eur. J. Med. Chem., 2014, 82, 314. 10.Li R. J.; Wu J. B.; He Y.; Hai L.; Wu Y.* Synthesis and in vitro evaluation of 12-(substituted aminomethyl) berberrubine derivatives as anti-diabetics. Bioorg. Med. Chem. Lett., 2014, 24, 1762.