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个人简介

药学院药物分析教研室主任。享受河北省政府特殊津贴专家,河北医科大学学术带头人,中国药学会药物分析专业委员会委员,河北省药学会理事,药物分析与天然药物专业委员会副主任委员,河北省中医药学会理事,河北省新药评审专家;药物分析杂志、中草药杂志、河北医科大学学报编委等。

研究领域

主要从事药品质量控制研究,从事化学药物和天然药物中有效成分与体内药物分析的研究,以及药物代谢和中药指纹(特征)图谱研究

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Investigating the in vitro stereoselective metabolism of m-nisoldipine enantiomers: Characterization of metabolites and cytochrome P450 isoforms involved. Biomedical Chromatography,2015,29(12):1893–1900. SCI收录,IF=1.876. 通讯作者 2. Simultaneous quantification of 16 bioactive constituents in Common cnidium fruit by liquid chromatography–electrospray ionization-mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis,107 (2015) 304–310. SCI收录,IF=1.876. 通讯作者 3. LC–MS/MS determination and pharmacokinetic study of seven flavonoids in rat plasma after oral administration of Cirsiumjaponicum DC. Extract. Journal of Ethnopharmacology,158(2014)66–75. SCI收录,IF=3.055. 通讯作者 4. A sensitive analysis method for 7 diterpenoids in rat plasma by liquid chromatography–electrospray ionization mass spectrometry and its application to pharmacokinetic study of Isodonserra extract. Journal of Chromatography A 1218 (2011) 7771–7780. SCI收录,IF=4.531. 通讯作者 5. Development of a novel method for triterpenoidalsaponins in rat plasma by solid-phase extraction and high-performance liquid chromatography tandem mass spectrometry. Analytical Biochemistry,419 (2011) 323–332. SCI收录,IF=3.236. 通讯作者 6. A rapid method for simultaneous determination of triterpenoidsaponins in Pulsatillaturczaninovii using microwave-assisted extraction and high performance liquid chromatography - tandem mass spectrometry. Food Chemistry,135 (2012) 251–258. SCI收录,IF=3.458,通讯作者 7. Determination of Cnidilin and Its Two Metabolites in Rat Plasma by High-performance Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry. Plata Medica,2013; 79: 30–36,SCI收录,IF=1.863. 通讯作者 8. Determination of cnidilin and its two metabolites in rat bile and stool after oral administration by HPLC/electrospray ionization tandem mass spectrometry. Biomedical Chromatography,2013; 27: 527–534. SCI收录,IF=1.762. 通讯作者 9. Simultaneous determination and pharmacokinetic study of six flavonoids from FructusSophorae extract in rat plasma by LC–MS/MS. Journal of Chromatography B, 904 (2012) 59– 64. SCI收录,IF=2.885. 通讯作者 10. Simultaneous determination of nine components in Anemarrhenaasphodeloides by liquid chromatography-tandem mass spectrometry combined with chemometric techniques. Journal of Separation Science,2012, 35, 1796–1807. SCI收录,IF=2.786. 通讯作者

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