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个人简介

2000 - 2004 四川大学, 学士 2004 - 2010 上海生命科学研究院,博士 2011 - 2014 美国南加州大学,博士后

研究领域

代谢与衰老生物学。衰老是生命发展的必经阶段,衰老与许多慢性疾病的产生,如癌症,肥胖和二型糖尿病等,有着密切的关系,这些疾病因此也可以称为衰老相关性疾病。本研究组以模式动物研究为基础,致力于解析衰老的遗传和代谢机制,并以此为基础探索延缓衰老及治疗衰老相关疾病的途径。

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Tang H, Pang S. Proline catabolism modulates innate immunity in C. elegans. Cell Reports 17(11): 2837-2844. (2016) 2. Pang S, Lynn D, Lo J, Curran SP. SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation. Nature Communications 5:5048. (2014). 3. Pang S, Curran SP. Adaptive capacity to bacterial diet modulates aging in C. elegans. Cell Metabolism 19(2): 221-231. (2014). (Previewed as a leading edge finding in Cell Metabolism 19(2): 177-178, 2014) 4. Pang S, Curran SP. Longevity and the long arm of epigenetics: acquired parental marks influence lifespan across several generations. Bioessays 34(8): 652-654. (2012) 5. Zhang L, Pang S, Deng B, Qian L, Chen J, Zou J, Zheng J, Yang L, Zhang C, Chen X, Liu Z, Le Y. High glucose induces renal mesangial cell proliferation and fibronectin expression through JNK/NF-κB/NADPH oxidase/ROS pathway, which is inhibited by resveratrol. Int J Biochem Cell Biol 44: 629-638. (2012) 6. Pang S, Tang H, Zhuo S, Zang YQ and Le Y. Regulation of fasting fuel metabolism by Toll-like receptor 4. Diabetes 59: 3041-3048. (2010) 7. Tang H, Pang S, Wang M, Xiao X, Rong Y, Wang H, Zang YQ. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice. J Immunol 185: 2563-2569. (2010) 8. Wang O, Cai K, Pang S, Wang T, Qi D, Zhu Q, Ni Z, Le Y. Mechanisms of glucose-induced expression of pancreatic-derived factor in pancreatic beta-cells. Endocrinology.149:672-680. (2008) 9. Pang S, Le Y. Role of resistin in inflammation and inflammation-related diseases. Cell Mol Immunol 3:29-34. (2006)

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