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招生专业 071010-生物化学与分子生物学 招生方向 表观遗传学

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1. Zhao Z., Lan M., Li J., Dong Q., Li X., Liu B., Li G., Wang H., Zhang Z.*, and Zhu B*., The proinflammatory cytokine TNFalpha induces DNA demethylation-dependent and -independent activation of interleukin-32 expression. J Biol Chem, 2019. 294(17): p. 6785-6795. PMID: 30824537 2. Zhang T., Guan X., Choi U.L., Dong Q., Lam M.M.T., Zeng J., Xiong J., Wang X., Poon T.C.W., Zhang H., Zhang X., Wang H., Xie R., Zhu B., and Li G.*, Phosphorylation of TET2 by AMPK is indispensable in myogenic differentiation. Epigenetics Chromatin, 2019. 12(1): p. 32. PMID: 31164154 3. Hou P., Huang C., Liu C.P., Yang N., Yu T., Yin Y., Zhu B.*, and Xu R.M.*, Structural Insights into Stimulation of Ash1L's H3K36 Methyltransferase Activity through Mrg15 Binding. Structure, 2019. 27(5): p. 837-845 e3. PMID: 30827843 4. Fu H., Liu N., Dong Q., Ma C., Yang J., Xiong J., Zhang Z., Qi X., Huang C., and Zhu B.*, SENP6-mediated M18BP1 deSUMOylation regulates CENP-A centromeric localization. Cell Res, 2019. 29(3): p. 254-257. PMID: 30631152 5. Du W., Dong Q., Zhang Z., Liu B., Zhou T., Xu R.M., Wang H., Zhu B.*, and Li Y.*, Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1. J Biol Chem, 2019. 294(22): p. 8907-8917. PMID: 31018966 6. Wu F., Zhang J., Shang E., Zhang J., Li X., Zhu B., and Lei X.*, Synthesis and Evaluation of a New Type of Small Molecule Epigenetic Modulator Containing Imidazo[1,2-b][1,2,4]triazole Motif. Front Chem, 2018. 6: p. 642. PMID: 30627529 7. Li Y., Zhang Z., Chen J., Liu W., Lai W., Liu B., Li X., Liu L., Xu S., Dong Q., Wang M., Duan X., Tan J., Zheng Y., Zhang P., Fan G., Wong J., Xu G.L., Wang Z., Wang H., Gao S., and Zhu B.*, Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1. Nature, 2018. 564(7734): p. 136-140. PMID: 30487604 8. Hong S., Zhang Z., Liu H., Tian M., Zhu X., Zhang Z., Wang W., Zhou X., Zhang F., Ge Q., Zhu B., Tang H.*, Hua Z.*, and Hou B.*, B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4(+) T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen. Immunity, 2018. 49(4): p. 695-708 e4. PMID: 30291027 9. Yu Z., Jiang K., Xu Z., Huang H., Qian N., Lu Z., Chen D., Di R., Yuan T., Du Z., Xie W., Lu X., Li H., Chai R., Yang Y., Zhu B., Kunieda T., Wang F.*, and Chen T.*, Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration. Cell Stem Cell, 2018. 23(4): p. 487-500 e6. PMID: 30122476 10. Dong Q., Li X., Wang C.Z., Xu S., Yuan G., Shao W., Liu B., Zheng Y., Wang H., Lei X., Zhang Z.*, and Zhu B.*, Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencing. Proc Natl Acad Sci U S A, 2018. 115(17): p. E4013-E4022. PMID: 29636421 11. Li X., Shang E., Dong Q., Li Y., Zhang J., Xu S., Zhao Z., Shao W., Lv C., Zheng Y., Wang H., Lei X., Zhu B.*, and Zhang Z.*, Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem, 2018. 293(19): p. 7423-7436. PMID: 29559556 12. Huang C., Yang F., Zhang Z., Zhang J., Cai G., Li L., Zheng Y., Chen S., Xi R.*, and Zhu B.*, Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila. Nature Communications, 2017. 8(1): p. 1649. PMID: 29158494 13. Li M., Dong Q., and Zhu B.*, Aurora Kinase B Phosphorylates Histone H3.3 at Serine 31 during Mitosis in Mammalian Cells. J Mol Biol, 2017. 429(13): p. 2042-2045. PMID: 28137420 14. Xiong J., Zhang Z.*, Chen J., Huang H., Xu Y., Ding X., Zheng Y., Nishinakamura R., Xu G.L., Wang H., Chen S., Gao S., and Zhu B.*, Cooperative Action between SALL4A and TET Proteins in Stepwise Oxidation of 5-Methylcytosine. Mol Cell, 2016. 64(5): p. 913-925. PMID: 27840027 15. Shang E., Zhang J., Bai J., Wang Z., Li X., Zhu B., and Lei X.*, Syntheses of [1,2,4]triazolo[1,5-a]benzazoles enabled by the transition-metal-free oxidative N-N bond formation. Chem Commun (Camb), 2016. 52(43): p. 7028-31. PMID: 27161847 16. Sun L., Zhang Y., Zhang Z., Zheng Y., Du L., and Zhu B.*, Preferential Protection of Genetic Fidelity within Open Chromatin by the Mismatch Repair Machinery. J Biol Chem, 2016. 291(34): p. 17692-705. PMID: 27382058 17. Dai C., Li W., Tjong H., Hao S., Zhou Y., Li Q., Chen L., Zhu B., Alber F.*, and Jasmine Zhou X.*, Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities. Nat Commun, 2016. 7: p. 11549. PMID: 27240697 18. Fu W., Liu N., Qiao Q., Wang M., Min J., Zhu B., Xu R.M.*, and Yang N.*, Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase. J Biol Chem, 2016. 291(17): p. 9173-80. PMID: 26929412 19. Sun J., Wei H.M., Xu J., Chang J.F., Yang Z., Ren X., Lv W.W., Liu L.P., Pan L.X., Wang X., Qiao H.H., Zhu B., Ji J.Y., Yan D., Xie T., Sun F.L.*, and Ni J.Q.*, Histone H1-mediated epigenetic regulation controls germline stem cell self-renewal by modulating H4K16 acetylation. Nat Commun, 2015. 6: p. 8856. PMID: 26581759 20. Liu N., Zhang Z., Wu H.*, Jiang Y., Meng L., Xiong J., Zhao Z., Zhou X., Li J., Li H., Zheng Y., Chen S., Cai T., Gao S., and Zhu B.*, Recognition of H3K9 methylation by GLP is required for efficient establishment of H3K9 methylation, rapid target gene repression, and mouse viability. Genes Dev, 2015. 29(4): p. 379-93. PMID: 25637356

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