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个人简介

2007年本科毕业于吉林大学材料科学与工程学院高分子材料系,2012年在中国科学技术大学获得博士学位,2015年1月加入华东师范大学,主要研究方向为抗感染及促修复材料,研究材料的结构与性能之间的关系,以及在眼、皮肤等局部感染以及全身性脓毒症感染模型中的应用。已在国际顶级期刊 Chemical Reviews,Nature communications, JACS, Nano Today,Biomateials,Journal of Controlled Release,Advaned Functional Materials等发表SCI研究论文40余篇,其中第一作者/通讯作者论文20余篇。 教育经历 2007/09–2012/07:中国科学技术大学,应用化学系,理学博士 2003/09–2007/07:吉林大学,高分子材料与工程系,工学学士 工作经历 2018/01-至今:华东师范大学,生命科学与技术学院,副研究员 2015/01-2017.12:华东师范大学,生命科学与技术学院,助理研究员 2012/09–2014/12:大连理工大学,生命科学与技术学院,博士后 荣誉及奖励 第五届全国大学生生命科学创新创业大赛“指导教师特等奖(创新类)” 第六届中国国际“互联网+”大学生创新创业大赛上海赛区优秀指导教师

研究领域

主要研究方向包括抗菌材料与水凝胶材料: 1)新型抗感染高分子材料及抗菌肽材料的构筑及应用 2)抗多耐药菌感染的生物材料 3)多刺激响应性智能生物医用水凝胶

近期论文

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J.J. Hu,N. Liu, Q.Q.Fan, Y.Q.Gu, S.J.Chen,F.Z., Y.Y.Cheng*.A Fluorous Peptide Amphiphile with Potent Antimicrobial Activityfor the Treatment of MRSA-induced Sepsis and Chronic WoundInfection.Angew. Chem. Int. Ed.,2024, e202403140.(IF:16.6) J.J. Hu, X. J. Zhou, S.J. Chen, D. Yin, Y.H. Yang, M.J. Chen, C.Y. Gui, Y.J. Cai, J.X. Hong, Y.Y. Cheng. A supramolecular gel with unique rheological properties for treating corneal virus infection.Nano Today, 2023, 101841. (IF:18.962) Y.X. Yang, Y.Q. Gu, K.Y. Chen, J.J. Luo, Z.J. Cheng, Y.Y Cheng*, J.J. Hu*. A polymyxin and cellulase based smart hydrogel for localized infection treatment and biofilm eradication.Giant, 2023, 100187. (IF:7) X.J. Cheng, H.Y. Chen, F. Yang, J.X. Hong*, Y.Y. Cheng*,J.J. Hu*. All-small-molecule supramolecular hydrogels assembled from guanosine 5′-monophosphate disodium salt and tobramycin for the treatment of bacterial keratitis.Bioact. Mater.,2022, 16, 293-300. (IF:17.3639) L. Li, X.J. Cheng, Q. Huang, Y.Y Cheng*, J.R. Xiao*,J.J. Hu*. Sprayable Antibacterial Hydrogels by Simply Mixing of Aminoglycoside Antibiotics and Cellulose Nanocrystals for the Treatment of Infected Wounds.Adv. Healthc. Mater., 2022, 11, 2201286. (IF:9.933) J.J. Hu, S.J. Chen, Y.X. Yang, L. Li, X.J. Cheng, Y.Y. Cheng*, Q. Huang*. A Smart Hydrogel with Anti-Biofilm and Anti-Virulence Activities to Treat Pseudomonas aeruginosa Infections.Adv. Healthc. Mater., 2022, 11, 2200299. (IF:9.933) J.J. Hu, L. Yang, X.J. Cheng, Y.W. Li, Y.Y. Cheng*. Aminoglycoside-Based Biomaterials: From Material Design to Antibacterial and Gene Delivery Applications.Adv. Funct. Mater.,2021, 31, 2103718. (IF:19.9775) J.J. Hu, C.L. Zhang, L. Zhou, Q.Y. Hu, Y.L. Kong, D.W. Song, Y.Y. Cheng*, Y.D. Zhang*. A smart hydrogel for on-demand delivery of antibiotics and efficient eradication of biofilms.Sci. China Mater., 2021, 64(4): 1035-1046. (IF:8.273) J.J. Hu, Q.Y. Hu, X. He, C.X. Liu, Y.L. Kong, Y.Y. Cheng*, Y.D. Zhang*. Stimuli-Responsive Hydrogels with Antibacterial Activity Assembled from Guanosine, Aminoglycoside, and a Bifunctional Anchor.Adv. Healthc. Mater., 2020, 1901329. (IF:6.27) J.J. Hu, H. Wang, Q.Y. Hu, Y.Y. Cheng*. G-quadruplex-based antiviral hydrogels by direct gelation of clinical drugs.Mater. Chem. Front., 2019, 3, 1323-1327. (IF:8.683) J. Hu, Z. Zheng, C.X. Lui, Q.Y. Hu, X.P. Cai, J.R. Xiao, Y.Y. Cheng*. A pH-responsive hydrogel with potent antibacterial activity against both aerobic and anaerobic pathogens.Biomater. Sci., 2019,7,581-584. (IF:5.251) T. Dai, C. Wang, Y. Wang, W. Xu,J.J Hu, Y.Y Cheng*. A Nanocomposite hydrogel with potent and broad-spectrum antibacterial activity.ACS Appl. Mater. Interfaces, 2018, 10, 15163-15173.(IF:8.097) Z. Zheng,J.J. Hu, H. Wang, J.L. Huang, Y.H. Yu, Q. Zhang, Y.Y. Cheng*. Dynamic Softening or Stiffening a Supramolecular Hydrogel by Ultraviolet or Near-Infrared Light.ACS Appl. Mater. Interfaces, 2017, 9 (29), 24511–24517.(IF:8.097) J.J. Hu, Y.C. Quan, Y.P. Lai, Z. Zheng, Z.Q. Hu, X.Y. Wang, T.J. Dai, Q. Zhang, Y.Y. Cheng*. A smart aminoglycoside hydrogel with tunable gel degradation, on-demand drug release, and high antibacterial activity.J. Control. Release, 2017, 247, 145-152.(IF:11.467) J.J. Hu,Y.H. Chen, Y.Q. Li, Z.J. Zhou, Y.Y. Cheng*. A thermo-degradable hydrogel with light-tunable degradation and drug release.Biomaterials,2017, 112, 133-140.(IF:15.304) J.J. Hu,K. Hu, Y.Y. Cheng*. Tailoring the dendrimer core for efficient gene delivery.Acta Biomater.2016, 35, 1-11. (IF:6.025) J.J. Hu, T.W. Xu, Y.Y. Cheng*. NMR insights into dendrimer-based host-guest systems. Chem. Rev.,2012, 112(7), 3856-3891. (IF:46.568) J.J. Hu, Y.Z. Su, H.F. Zhang, T.W. Xu*, Y.Y. Cheng*. Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery. Biomaterials,2011, 32, 9950-9959. (IF:8.557) J.H. Zhang, J.J. Hu, X.Y. Feng, Y.W. Li, L.B. Zhao, T.W. Xu*, Y.Y. Cheng*. Interactions between Oppositely Charged Dendrimers. Soft Matter, 2012, 8, 9800-9806. (IF:4.029) J.J. Hu, Y.Y. Cheng*, Y.R. Ma, Q.L. Wu, and T.W. Xu*. Host-Guest Chemistry and Physicochemical Properties of the Dendrimer-Mycophenolic Acid Complex. J. Phys. Chem. B 2009, 113, 64-74. (IF:3.302). J.J. Hu, Y.Y. Cheng*, Q.L. Wu, L.B. Zhao, and T.W. Xu*. Host-Guest Chemistry of Dendrimer-Drug Complexes. 2. Effects of Molecular Properties of Guests and Surface Functionalities of Dendrimers. J. Phys. Chem. B 2009, 113, 10650-10659. (IF:3.302) J.J. Hu, M. Fang, Y.Y. Cheng*, J.H. Zhang, Q.L. Wu, and T.W. Xu*. Host-Guest Chemistry of Dendrimer-Drug Complexes. 4. An In-depth Look into the Binding/Encapsulation of Guanosine Monophosphate by Dendrimers. J. Phys. Chem. B 2010, 114, 7148-7157. (IF:3.302) J.J. Hu, K. Hu, Y.Y. Cheng. Targeted dendrimers for cancer diagnosis and therapy. (John Wiely, ISBN: 978352733

学术兼职

上海市科技项目评审专家 全国大学生生命科学竞赛评审专家 全国大学生互联网+生命科学创新创业大赛评审专家 上海市生物材料协会会员 全国高分子生物材料协会会员 Journal of Controlled Release,Chemical Engineering Journal等国际SCI期刊审稿人

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