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个人简介

主要以肿瘤干细胞自我更新核心特性为切入点,探讨肿瘤干细胞自我更新及其在肿瘤发生和转移中的作用机制,为肿瘤的临床肿瘤干细胞靶向治疗与个体化治疗提供理论支撑。 采用二代测序,蛋白质组等组学技术研究妇科肿瘤分子分型,探索妇科肿瘤个体化治疗策略。相关研究成果在Gastroenterology、Journal of Hepatology、Clinical cancer research、Advanced Science 等期刊发表SCI论文7篇。累计主持省部级以上项目4项,获国家授权专利4项;上海市科技进步一等奖1项(2017)。上海市“青年科技启明星”(2019)。

研究领域

肿瘤干细胞及表观遗传学调控在肿瘤发生与转移中的作用机制研究 妇科肿瘤精准诊疗及个体化治疗

近期论文

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Liu Shupeng#; Cheng Kai#; Zhang Hui; Kong Ruijiao; Wang Shuo; Mao Chuanbin*; Liu Shanrong*; Methylation Status of the Nanog Promoter Determines the Switch between Cancer Cells and Cancer Stem Cells, Advanced Science, 2020, 7(5): 201903035.1-11. Zhu, Yan#; Chen, Peizhan#; Gao, Yisha; Ta, Na; Zhang, Yunshuo; Cai, Jialin; Zhao, Yong; Liu, Shupeng*; Zheng, Jianming*; MEG3 Activated by Vitamin D Inhibits Colorectal Cancer Cells Proliferation and Migration via Regulating Clusterin , EBioMedicine, 2018, 30: 148-157. Guo Weixing#; Liu Shupeng#; Cheng Yuqiang#; Lu Lei; Shi Jie; Xu Guixia; Li Nan; Cheng Kai; Wu Mengchao; Cheng Shuqun*; Liu Shanrong*; ICAM-1-Related Noncoding RNA in Cancer Stem Cells Maintains ICAM-1 Expression in Hepatocellular Carcinoma , Clinical Cancer Research, 2016, 22(8): 2041-2050. Liu, Shupeng#; Li, Nan#; Yu, Xiya#; Xiao, Xiao; Cheng, Kai; Hu, Jingjing; Wang, Jiaqi; Zhang, Dandan; Cheng, Shuqun*; Liu, Shanrong*; Expression of Intercellular Adhesion Molecule 1 by Hepatocellular Carcinoma Stem Cells and Circulating Tumor Cells, GASTROENTEROLOGY, 2013, 144(5): 1031-1041. Liu, Shupeng#; Guo, Weixing#; Shi, Jie; Li, Nan; Yu, Xiya; Xue, Jie; Fu, Xiaohui; Chu, Kaijian; Lu, Chongde; Zhao, Jiangsha; Xie, Dong; Wu, Mengchao; Cheng, Shuqun*; Liu, Shanrong*; MicroRNA-135a contributes to the development of portal vein tumor thrombus by promoting metastasis in hepatocellular carcinoma, Journal of Hepatology, 2012, 56(2): 389-396. Liu, Shupeng#; Zhou, Zaixin#; Jia, Yin; Xue, Jie; Liu, Zhiyong; Cheng, Kai; Cheng, Shuqun; Liu, Shanrong*; Identification of portal vein tumor thrombus with an independent clonal origin in hepatocellular carcinoma via multi-omics data analysis , Cancer Biology & Medicine, 2019, 16(1): 147-170. Li Bin#; Zhu Yan#; Xie Lei; Hu Shuyang; Liu Shupeng*; Jiang Xiaoqing*; Portal vein ligation alters coding and noncoding gene expression in rat livers , Biochemistry and Cell Biology, 2018, 96(1): 1-10.

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