王凯 - 同济大学

个人简介

主持科研项目重点研发计划（编号：2017YFA0104600）“人类上皮组织再生机制研究”，2017.07-2021.12 RMB 2668万（项目骨干）中央高校基本科研业务费专项资金(同济大学) “芳香烃受体在早期妊娠失败中的作用机制。”项目负责人，2015.07-2017.06, RMB 200,000 国家自然科学基金面上项目 (编号：81270703) “长期低氧对胎盘血管生成的影响及分子机制” 项目负责人，2013.01-2016.12, RMB 700,000 国家自然科学基金青年项目 (编号：81100429) “芳香烃受体介导的二噁英类环境污染物TCDD对胎盘血管发育的影响及其分子机制.” 项目负责人，2012.01-2014.12, RMB 220,000 上海市自然科学基金 (编号：11ZR1428700) “芳香烃受体(AhR)在胎盘血管生成中的作用”。项目负责人，2011.03-2014.04, RMB 100,000 中央高校基本科研业务费专项资金(同济大学) “芳香烃受体在人滋养层细胞侵袭中的作用。”项目负责人，2012.01-2013.12, RMB 200,000 2012年上海市浦江人才计划资助项目（12PJ1407300） “长期低氧对胎盘血管生成的影响及分子机制”项目负责人，2013.01-2015.12, RMB 200,000

研究领域

妇科肿瘤内分泌生殖生理

近期论文

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Chang X, Bian Y, He Q, Yao J, Zhu J, Wu J, Wang K*, Duan T*. Suppression of STAT3 Signaling by Δ9-Tetrahydrocannabinol (THC) Induces Trophoblast Dysfunction. Cell Physiol Biochem. 2017 ;42:537-550. Wu JT, Yao JL, Wang K*, Duan T*. expression of lysyl oxidase (LOX) in human placental amnion in preterm labor. Int J Clin Exp Pathol 2016;9:9231-9236. Zhou J, Ni XT, Huang XJ, Yao JL, He QZ, Wang K*, Duan T*. Potential role of hyperglycemia in fetoplacental endothelial dysfunction in gestational diabetes mellitus. Cell Physiol Biochem. 2016;39(4):1317-28. Bian Y, Chang X, Liao Y, Wang J, Li Y, Wang K*, Wan XP*. Promotion of epithelial-mesenchymal transition by Frizzled2 is involved in the metastasis of endometrial cancer. Oncol Rep. 2016;36:803-10. Chang X, Bian Y, Wu Y, Huang Y, Wang K*, Duan T*. Endocan of the maternal placenta tissue is increased in pre-eclampsia. Int J Clin Exp Pathol. 2015;8:14733-40. Wu Y, Chen X, Chang X, Huang YJ, Bao S, He Q, Li Y, Zheng J, Duan T*, Wang K*. Potential Involvement of Placental AhR in Unexplained Recurrent Spontaneous Abortion. Reprod Toxicol. 2016;59:45-52. Huang YJ, Wu YM, Chang XW, Li Y, Wang K*, Duan T*. Effects of Human Umbilical Cord Mesenchymal Stem Cells on Human Trophoblast Cell Functions In Vitro. Stem Cells Int.2016:9156731. Li Y, Jia Y, Che Q, Zhou Q, Wang K*, Wan XP*. AMF/PGI-mediated tumorigenesis through MAPK-ERK signaling in endometrial carcinoma. Oncotarget. 2015;6:26373-87. Li Y, Che Q, Bian Y, Zhou Q, Jiang F, Tong H, Ke J, Wang K*, Wan XP*. Autocrine motility factor promotes epithelial-mesenchymal transition in endometrial cancer via MAPK signaling pathway. Int J Oncol. 2015;47:1017-24. Li Y, Wang K*, Zou QY, Zhou C, Magness RR, Zheng J. A possible role of aryl hydrocarbon receptor in spontaneous preterm birth. Med Hypotheses. 2015;84:494-7. Shen ZJ, Wu YM, Chen X, Chang XW, Zhou Q, Zhou J, Ying H, Zheng J, Duan T*, Wang K*. Decreased Maternal Serum 2-Methoxyestradiol Levels are Associated with the Development of Preeclampsia. Cell Physiol Biochem 2014;34:2189-2199. Li Y, Wang K*, Jiang YZ, Chang XW, Dai CF, Zheng J. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) inhibits human ovarian cancer cell proliferation. Cell Oncol. 2014;37:429–437. Wu Y, Chen X, Zhou Q, He Q, Kang J, Zheng J, Wang K*, Duan T*. ITE and TCDD Differentially Regulate the Vascular Remodeling of Rat Placenta via the Activation of AhR. PLoS One. 2014;9(1):e86549. Wang K*, Li Y*, Jiang YZ, Dai CF, Patankar MS, Song JS, Zheng J. An Endogenous Aryl Hydrocarbon Receptor Ligand Inhibits Proliferation and Migration of Human Ovarian Cancer Cells. Cancer Lett. 2013;340:63-71.