孙祖俊 - 同济大学

研究领域

肿瘤发病机制、生物标志物筛查及免疫治疗的基础和临床研究

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Exosomal circPACRGL promotes progression of colorectal cancer via the miR-142-3p/miR-506-3p-TGF-β1 axis. Mol Cancer, 2020, 19:117-31； Long Non-coding RNA CCAT1 promotes colorectal cancer progression by regulating miR-181a-5p expression. Aging (Albany NY). 2020, 12(9): 8301-8320； Exosomal miR-183-5p Promotes Angiogenesis in Colorectal Cancer by Regulation of FOXO1. Aging (Albany NY). 2020, 12(9): 8352-8371； Exosomal KRAS mutation promotes the formation of tumor-associated neutrophil extracellular traps and causes deterioration. Cell Commun Signal. 2020, 18(1):52； Long non-coding RNA HOTTIP enhances IL-6 expression to potentiate immune escape of ovarian cancer cells by upregulating the expression of PD-L1 in neutrophils. Journal of Experimental & Clinical Cancer Research. 2019, 38:1-15； Myeloid cell-derived LL-37 promotes lung cancer growth by activating Wnt/β-catenin signaling. Theranostics. 2019, 9(8):2209-23； Bronchoalveolar lavage fluid-derived exosomes: a novel role contributing to lung cancer growth. Frontiers in Oncology. 2019,197:1-11； A novel humanized anti-PD-1 monoclonal antibody potentiates therapy in oral squamous cell carcinoma. Ivest New Drug. 2018, 26(6):1-12； A deficiency in cathelicidin reduces lung tumor growth in NNK/NTHi-induced A/J mice. Am J Cancer Res. 2018, 8:1190-9； The value of red blood cell distribution width in diagnosis of patients with colorectal cancer. Clinica Chimica Acta. 2018, 479: 98-102； Role of c-Met in the progression of human oral squamous cell carcinoma and its potential as a therapeutic target. Oncol Rep. 2018, 39: 209-216； A novel bispecific c-MET/PD-1 antibody with therapeutic potential in solid cancer. Oncotarget. 2017, 8: 29067-79； Overexpression of SENP3 in oral squamous cell carcinoma and its association with differentiation. Oncol Rep. 2013, 29:1701-6； Role of toll-like receptor 4 on the immune escape of human oral squamous cell carcinoma and resistance of cisplatin-induced apoptosis. Mol Cancer. 2012. 11:1-12