范列英 - 同济大学

个人简介

现任同济大学附属东方医院医学检验科主任，同济大学临床医学三系实验诊断学教研室主任，主任医师、教授，博士及硕士研究生导师。1985年毕业于第一军医大学医疗系，1993年获第二军医大学临床医学硕士学位，1997年获第二军医大学临床医学博士学位，并先后在德国Johennas Gutenburg 学院临床医学院及德国欧蒙实验诊断中心访问与工作。长期从事临床实验研究和临床检验诊断工作，研究主要涉及心脑血管疾病、自身免疫性疾病发病机制、实验室诊断和治疗领域，已经完成上海市科委、市卫生局等多项课题研究工作，以主要作者身份获得军队科技进步一等奖一项、二等奖二项，上海市科技进步奖二项。作为第一负责人先后承担国家自然基金、上海市自然基金、上海市科委基础研究重点项目、上海市科委国际合作项目及浦东新区科委创新攻关项目和重点协作项目等多项研究课题，同时参与国家973计划、863计划和十一·五科技支撑计划课题研究。2012年入选上海市优秀学术带头人计划。在国内核心学术期刊上发表论文100余篇，在《Eur Heart J》、《Biomaterials》、《Tissue Antigen》、《Clinica Chimica Acta》等国外SCI杂志上发表论文18篇，主编出版专著1部、参编专著5部。主要任职上海市医学会检验医学分会委员，临床生化专业组组长上海市临检中心临床检验质控专家委员会委员上海市免疫学会免疫技术专业委员会副主任委员中国免疫学会临床免疫分会委员中国医师协会风湿免疫病科医师分会自身免疫病实验室诊断技术专家委员中国微生物临床微生物学专业委员会委员中国合格评定委员会医学实验室评审员浦东新区医学会检验学组组长《检验医学》杂志编委《中华临床医师》杂志特约编辑 CCA （Clinica Chimica Acta）、Immunology Investigation 审稿专家

研究领域

免疫性疾病实验室诊断、发病机制及防治研究

近期论文

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Fan LY, He DY, Wang Q, Zong M, Zhang H, Yang L, Sun LS. Citrullinated vimentin stimulates proliferation, pro-inflammatory cytokine secretion, and PADI4 and RANKL expression of fibroblast-like synoviocytes in rheumatoid arthritis. Scand J of Rheumatol [Ahead of Print] Zhang CS, Fan LY( Correspondence author.), Fan TT, Wu D, Gao L, Ling Y, Zhu J, Li R, Wei LX. Decreased PADI4 mRNA association with global hypomethylation in Hepatocellular Carcinoma during HBV exposure. Cell Biochemistry and Biophysics. 2012[ recepted]. Zhang H, Fan LY(*contributed equally to this work, Correspondence author.), Zong M, L. Sun LS, Lu L. Proteins related to the functions of fibroblast-like synoviocytes identified by proteomic analysis. Clin Exp Rheumatol 2012,30: 213-221. Fan LY, Zong M, Wang Q, Yang L, Sun LS, Ye Q, Ding YY, Ma JW. Diagnostic value of Glucose-6-Phosphate Isomerase in Rheumatoid Arthritis. Clinica Chimica Acta 2010,411:2049-2053 Fan LY, Wang, WJ, Wang Q, Zong M, Yang L, Zhang H, Sun LS, Lu TB, Han J. A functional haplotype and expression of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Chinese. Tissue Antigens 2008;72: 469-73. Zhang J*, Wang GY*, Xiao YP*, Fan LY*(*contributed equally to this work.), Wang Q. The biomechanical behavior and host response to porcine-derived small intestine submucosa, pericardium and dermal matrix acellular grafts in a rat abdominal defect model. Biomaterials 2011,32(29):7086-95. Ling Y*, Huang GL*, Fan LY(*contributed equally to this work.), Wei LX, Zhu J, Liu YP, Zhu CT, Zhang CS. CpG island methylator phenotype of cell-cycle regulators associated with TNM stage and poor prognosis in patients with oesophageal squamous cell carcinoma J Clin Pathol 2011,64(3):246-51. Fan LY. Genetics association of vitamin D receptor polymorphsims with autoimmune hepatitis and primary biliary cirrhosis in the Chinese. J Gastroenterolog & Hepatology 2005,20(2):249-55 Fan LY. Genetic Association of Cytokines polymorphisms with Autoimmune Hepatitis and Primary Biliary Cirrhosis in the Chinese. World J Gastroentology 2005,11(18):2768-2772. Fan LY, et al. CTLA-4 gene polymorphisms confer susceptibility to primary biliary cirrhosis and autoimmune hepatitis in a Chinese population. World J Gastroenterology, 2004. IF: 2.532 Fan LY, Dong CL,Zhu J, Liu Y, Ni Y, Zhu C, Zhang CS. Combined influence of adjuvant therapy and interval after surgery on peripheral CD4+ T lymphocytes in patients with esophageal squamous cell carcinoma. Experimental and Therapeutic Medicine, 2010,1:113-120