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个人简介

主持课题 国家自然科学基金 青年基金,树突状细胞源外泌体miRNA-126对小鼠心肌梗死后血管新生的作用及机制研究,起止年月2014.1.1-2017.12.31,主持,科研经费 23万 国家自然科学基金 面上项目,CCR7在急性心肌梗死后对树突状细胞来源的外泌体迁移至淋巴组织的调控作用,起止年月 2018.1.1-2021.12.31,主持,科研经费 52万 心血管健康研究院临床科学家菁英培训计划,炎症因子指导PCI术后强化他汀治疗的价值研究,起止年月 2018.1.1-2019.12.31,主持,科研经费 10万

研究领域

冠心病免疫炎症研究及冠心病介入治疗

近期论文

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Exosomes derived from dendritic cells improve cardiac function via activation of CD4(+) T lymphocytes after myocardial infarction. J Mol Cell Cardiol. 2016 Feb;91:123-33. MicroRNA-378 suppresses myocardial fibrosis through a paracrine mechanism at the early stage of cardiac hypertrophy following mechanical stress. Theranostics. 2018 Apr 3;8(9):2565-2582. Prognostic Value of Plasma Pentraxin-3 Levels in Patients with Stable Coronary Artery Disease after Drug-Eluting Stent Implantation. Mediators inflamm. 2014; 2014: 963096. Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF-α mediated NF-κB pathway. J Cell Mol Med. 2016 Dec;20(12):2318-2327. Retrograde percutaneous coronary intervention of native right coronary artery chronic total occlusion via left internal mammary artery graft. Int J Cardiol. 2016 Feb 15;205:86-88. Pentraxin-3 Predicts Long-Term Cardiac Events in Patients with Chronic Heart Failure. Biomed Res Int. 2015;2015:817615. Dendritic cells derived exosomes migration to spleenand induction of inflammation are regulated by CCR7. Sci Rep. 2017 Feb 22;7:42996. Congenital absence of the right coronary artery with superdominant left circumflex coronary artery. Int J Cardiol. 2012 Jun 28;158(1):e13-4.

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