个人简介
霍敏锋，男，中共党员，同济大学特聘研究员，博士生导师，同济大学附属第十人民医院双聘PI。博士毕业于中国科学院上海硅酸盐研究所，后继续从事博士后研究（博导及合作导师：施剑林院士）。2022年加入同济大学医学院，研究工作聚焦纳米生物材料的可控制备、生物医学应用及关键机制研究。截止目前，以第一作者或通讯作者身份在 Nature Communications（2篇）, Angewandte Chemie International Edition, Advanced Materials, Matter, Advanced Functional Materials等高影响力杂志共发表论文23篇，论文总被引2800余次，h指数22。主持国家自然科学基金青年基金，上海市科委项目，中国博士后基金会面上资助（二等），中国科学院上海硅酸盐研究所所创新前瞻培育项目，国家重点实验室主任青年基金，入选2023年度上海市青年科技启明星、2020年度国家“博士后创新人才支持计划”。
主要任职
2019.7-2022.2 中国科学院上海硅酸盐研究所 特别研究助理（博士后）/ 助理研究员（自然科学）
2022.3至今 同济大学医学院特聘研究员
近期论文
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M. Huo, Z. Tang, L. Wang, L. Zhang, H. Guo, Y. Chen, P. Gu*, J. Shi*. Magnesium hexacyanoferrate nanocatalysts attenuate chemodrug-induced cardiotoxicity through an anti-apoptosis mechanism driven by modulation of ferrous iron. Nature Communications. 2022, 13: 7778. 2022/12/15.
M. Huo, L. Wang, Y. Chen* and J. Shi*. Tumor-selective catalytic nanomedicine by nanocatalyst delivery. Nature Communications. 2017, 8: 357. 2017/08/25.
M. Huo, L. Wang, L. Zhang, C. Wei, Y. Chen*, J. Shi*. Photosynthetic Tumor Oxygenation by Photosensitizer‐Containing Cyanobacteria for Enhanced Photodynamic Therapy. Angewandte Chemie International Edition, 2020, 59(5): 1906-1913. 2020/1/27.
M. Huo, P. Liu, L. Zhang, C. Wei, L. Wang*, Y. Chen*, J. Shi*. Upconversion Nanoparticles Hybridized Cyanobacterial Cells for Near‐Infrared Mediated Photosynthesis and Enhanced Photodynamic Therapy. Advanced Functional Materials, 2021, 31(16): 2010196. 2021/4/15.
M. Huo, L. Wang, Y. Wang, Y. Chen* and J. Shi*. Nanocatalytic Tumor Therapy by Single-Atom Catalysts. ACS Nano. 2019, 13(2), 2643-2653. 2019/2/12.
M. Huo, L. Wang, Y. Chen*, J. Shi*. Oxygen Pathology and Oxygen Functional Materials for Therapeutics. Matter, 2020, 2 (5): 1115-1147. 2020/5/6.
M. Huo, L. Wang, Y. Chen*, J. Shi*. Nanomaterials/Microorganism-integrated Microbiotic Nanomedicine. Nano Today, 2020, 32: 100854. 2020/6/1.
M. Huo, L. Wang, H. Zhang, L. Zhang, Y. Chen* and J. Shi*. Construction of Single-Iron-Atom Nanocatalysts for Highly Efficient Catalytic Antibiotics. Small. 2019, 15(31): 1901834. 2019/8/2.
Z. Tang#, M. Huo#, Y. Ju, X. Dai, N. Ni, Y. Liu, H. Gao, D. Zhang, H. Sun, X. Fan*, Y. Chen*, P. Gu*. Nanoprotection Against Retinal Pigment Epithelium Degeneration via Ferroptosis Inhibition. Small Methods, 2021, 5(12): 2100848. 2021/11/18.
M. Huo, Y. Chen* and J. Shi*. Triggered-release drug delivery nanosystems for cancer therapy by intravenous injection: where are we now? Expert Opinion on Drug Delivery. 2016, 13(9): 1195-1198. 2016/9/1.
J. Zuo, M. Huo*, L. Wang, J. Li, Y. Chen*, P. Xiong*. Photonic hyperthermal and sonodynamic nanotherapy targeting oral squamous cell carcinoma. Journal of Materials Chemistry B. 2020, 8: 9084-9093. 2020/08/21.
H. Chen, X. Li, M. Huo*, L. Wang, Y. Chen*, W Chen, B. Wang*. Tumor-responsive copper-activated disulfiram for synergetic nanocatalytic tumor therapy. Nano Research, 2021, 14: 205-211. 2020/10/06.
P. Liu, M. Huo*, J. Shi*. Nanocatalytic Medicine of Iron-Based Nanocatalysts. CCS Chemistry, 2020, 3(2): 2445-2463. 2021/2/1.
S. Sun, Y. Song, J. Chen, M. Huo*, Y. Chen*, L. Sun*. NIR -I and NIR-II irradiation tumor ablation using NbS2 nanosheets as the photothermal agent. Nanoscale, 2021, 13(43): 18300-18310. 2021/11/11.
F. Qi, P. Ji, Z. Chen, H. Yao, M. Huo*, J. Shi*. Photosynthetic Cyanobacteria-Hybridized Black Phosphorus Nanosheets for Enhanced Tumor Photodynamic Therapy. Small, 17(42), 2102113. 2021/10/21.
L. Wang, D. Lu, M. Huo*, H. Xu*. Oligomycin A Induces Apoptosis-to-Pyroptosis Switch against Melanoma with Sensitized Immunotherapy. Advanced Functional Materials, 2021, 32(4): 2106332. 2021/10/12.
X. Li, Y. Zhang, X. Ren, Y. Wang, D. Chen, Q. Li*, M. Huo*, J. Shi. Ischemic Microenvironment-Responsive Therapeutics for Cardiovascular Diseases. Advanced Materials, 2021, 2105348. 2021/12/29.
D. Lu, L. Wang, L. Wang, L. An, M. Huo*, H. Xu*, J. Shi. Probiotic Engineering and Targeted Sonoimmuno-Therapy Augmented by STING Agonist. Advanced Science, 2022, 9(22): 2201711. 2022/06/05.
P. Ji, S. Zhang, P. Liu, X. Li, W. Bao, X. Cui*, M. Huo*, J. Shi. Modulation of mitochondrial electron transport chain by pyroptosis for tumor destruction. Nano Today, 2022, 44: 101511. 2022/06/26.
X. Ren, D. Chen, Y. Wang, H. Li, Y. Zhang, H. Chen*, X. Li, M. Huo*. Nanozymes-recent development and biomedical applications. Journal of Nanobiotechnology, 2022, 20(1): 92. 2022/03/13.
Y. Zhang, X. Ren, Y. Wang, D. Chen, L. Jiang, X. Li, T. Li*, M. Huo*, Q. Li*. Targeting Ferroptosis by Polydopamine Nanoparticles Protects Heart against Ischemia/Reperfusion Injury. ACS Applied Materials and Interfaces. 2022, 13(45): 53671-53682. 2022/02/17.
P. Liu, P. Ji, L. Wang, H. Guo, M. Huo*, J. Shi*. Concurrent antibiosis and anti-inflammation against bacterial pneumonia by zinc hexacyanoferrate nanocatalysts. Biomaterials, 2022, 289: 121768. 2022/8/30.
P. Ji, B. An, Z. Jie, L. Wang, S. Qiu, C. Ge, Q. Wu, J. Shi, M. Huo*. Genetically engineered probiotics as catalytic glucose depriver for tumor starvation therapy. Materials Today Bio, 2023, 18: 100515. 2022/12/15.
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