唐本忠 - 香港中文大学（深圳）

个人简介

教育背景博士后（多伦多大学）博士（京都大学）硕士（京都大学）学士（华南理工大学）唐本忠教授1982年获华南理工大学学士学位，1985年、1988年先后获日本京都大学硕士、博士学位。曾在多伦多大学从事博士后研究、日本NEOS公司中央研究所任高级研究员。1994–2021年在香港科技大学工作。2009年、2017年、2020年先后当选中国科学院院士、亚太材料科学院院士、发展中国家科学院院士。2021年加入香港中文大学（深圳）担任理工学院院长、校长学勤讲座教授。主要从事高分子化学和先进功能材料研究。在聚集诱导发光（Aggregation-Induced Emission, AIE）这一化学和材料前沿领域取得了原创性成果，是AIE概念的提出者和AIE研究的引领者。已发表学术论文2,000多篇，总引用超180,000次，h因子为187。在学术会议上作了500多场邀请报告，拥有100多项授权专利。现任德国Wiley出版社发行的Aggregate《聚集体》杂志主编以及20多家国际科学杂志顾问、编委或客座编辑等。 2014年至今连续当选全球材料和化学双领域“高被引科学家”。2007年获Croucher基金会高级研究员奖，2012年获美国化学会高分子材料科学与工程分会MACRO讲座奖，2014年获伊朗国家科技部颁发的Khwarizmi国际奖，2015年获广州市荣誉市民称号，2017年获国家自然科学一等奖、何梁何利基金科学与技术进步奖，2021年获Nano Today国际科学奖，2023年获生物材料全球影响力奖。

研究领域

新型光学（AIE）分子/药物开发及生物学应用。研究方向如下： 1）胞内耐药菌感染诊疗光学分子/药物研发及相关机制研究，宿主导向胞内耐药菌治疗策略探究 2）光学多功能抗菌材料/药物研发，耐药病原菌感染诊疗、成像及杀伤相关机制研究 3）光学纳米药物载体构建，癌症光学和免疫诊疗及机制研究 4）病原微生物检测，肿瘤标志物检测试剂盒研发

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

Robust Supramolecular Nanotunnels Built from Molecular Bricks Angew. Chem. Int. Ed. 2021, 60, in press. Solid-State Intramolecular Motions in Continuous Fibers Driven by Ambient Humidity for Fluorescent Sensors Nat. Sci. Rev. 2021, in press. Efficient Killing of Multidrug-Resistant Internalized Bacteria by AIEgens in Vivo Adv. Sci. 2020, in press. Revisiting an Ancient Inorganic Aggregation-Induced Emission System: An Enlightenment to Clusteroluminescence Aggregate 2021, 2, in press. Enantiomeric Switching of the Circularly Polarized Luminescence Processes in a Hierarchical Biomimetic System by Film Tilting ACS Nano 2021, 15, 1397. Single Injection and Multiple Treatments: An Injectable Nanozyme Hydrogel as AIEgen Reservoir and Release Controller for Efficient Tumor Therapy Nano Today 2021, 37, 101091. Zwitterionic AIEgens: Rational Molecular Design for NIR-II Fluorescence Imaging-Guided Synergistic Phototherapy Adv. Funct. Mater. 2021, 31, 2007026. Unusual Light-Driven Amplification through Unexpected Regioselective Photogeneration of a Five-Membered Azaheterocyclic AIEgen Chem. Sci. 2021, 12, 709. Development of Reaction-Based AIE Handy Pen for Visual Detection of Toxic Vapors ACS Mater. Lett. 2021, 3, 249. Substitution Activated Precise Phototheranostics through Supramolecular Assembly of AIEgen and Calixarene J. Am. Chem. Soc. 2020, 142, 15966. Molecular Motions in AIEgen Crystals: Turning on Photoluminescence by Force-Induced Filament Sliding J. Am. Chem. Soc. 2020, 142, 14608. Planar Plus Twisted Molecular Structure Leads to High Brightness of Semiconducting Polymer Nanoparticles for NIR-IIa Fluorescence Imaging J. Am. Chem. Soc. 2020, 142, 15146. Reverse Thinking of Aggregation-Induced Emission Principle: Amplifying Molecular Motions to Boost Photothermal Efficiency of Nanofibers Angew. Chem. Int. Ed. 2020, 59, 20371. Exosome-Mimetic Supramolecular Vesicles with Reversible and Controllable Fusion and Fission Angew. Chem. Int. Ed. 2020, 59, 21510. Natural-Killer Cell-Inspired Nanorobots with Aggregation-Induced Emission Characteristics for Near-Infrared-II Fluorescence-Guided Gliomas Theranostics ACS Nano 2020, 14, 11452. Controllable and Diversiform Topological Morphologies of Self-Assembling Supra-Amphiphiles with Aggregation-Induced Emission Characteristics for Mimicking Light-Harvesting Antenna Adv. Sci. 2020, 7, 2001909. An Intelligent AIEgen with Nonmonotonic Multiresponses to Multistimuli Adv. Sci. 2020, 7, 2001845. Less is More: Silver-AIE Core@Shell Nanoparticles for Multimodality Cancer Imaging and Synergistic Therapy Biomaterials 2020, 238, 119834. Tuning Molecular Emission of Organic Emitters from Fluorescence to Phosphorescence through Push-Pull Electronic Effects Nature Commun. 2020, 11, 2617. A Flexible Topo-optical Sensing Technology with Ultrahigh Contrast Nature Commun. 2020, 11, 1448. Design of AIEgens for Near-Infrared IIb Imaging through Structural Modulation at Molecular and Morphological Levels Nature Commun. 2020, 11, 1255. Tuning Push-Pull Electronic Effects of AIEgens to Boost Theranostic Efficacy for Colon Cancer J. Am. Chem. Soc. 2020, 142, 11442. Phage-Guided Targeting, Discriminated Imaging and Synergistic Killing of Bacteria by AIE Bioconjugates J. Am. Chem. Soc. 2020, 142, 3959. Tumor-Exocytosed Exosome/AIEgen Hybrid Nano-vesicles Facilitate Efficient Tumor Penetration and Photodynamic Therapy Angew. Chem. Int. Ed. 2020, 59, 13836. ACQ-to-AIE Transformation: Tuning Molecular Packing by Regioisomerization for Two-photon NIR Bioimaging Angew. Chem. Int. Ed. 2020, 59, 12822. Crystallization-Induced Reverse from Dark to Bright Excited Statesfor Construction of Solid-Emission-Tunable Squaraines Angew. Chem. Int. Ed. 2020, 59, 10136. Fluorescence Self-reporting Precipitation Polymerization Based on Aggregation-Induced Emission for Constructing Optical Nanoagents Angew. Chem. Int. Ed. 2020, 59, 10122. An AIE Conjugated Polymer with Ultra-strong ROS Generation Ability and Great Biosafety for Efficient Therapy of Bacterial Infection Angew. Chem. Int. Ed. 2020, 59, 9952. A Conjugated Polymeric Supramolecular Network with Aggregation‐Induced Emission Enhancement: An Efficient Light‐Harvesting System with an Ultrahigh Antenna Effect Angew. Chem. Int. Ed. 2020, 59, 9908. Principles of Aggregation-Induced Emission: Design of Deactivation Pathways for Advanced AIEgens and Applications Angew. Chem. Int. Ed. 2020, 59, 9856. Author Profile Angew. Chem. Int. Ed. 2020, 59, 9811. Three-Pronged Attack by Homologous Far-Red/NIR AIEgens to Achieve ‘1+1+1>3’ Synergistic Enhanced Photodynamic Therapy Angew. Chem. Int. Ed. 2020, 59, 9610. Time-dependent Photodynamic Therapy for Multiple Targets: A Highly Efficient AIE-active Photosensitizer for Selective Bacterial Elimination and Cancer Cell Ablation Angew. Chem. Int. Ed. 2020, 59, 9470. New Wine in Old Bottle: Prolonging Room-Temperature Phosphorescence of Crown Ethers by Supramolecular Interactions Angew. Chem. Int. Ed. 2020, 59, 9293. Dancing Brightly Under Light: Intriguing Photomechanical Luminescence in Constructing Through-Space Conjugated AIEgens Angew. Chem. Int. Ed. 2020, 59, 8828. Unusual Through-Space Interactions between Oxygen Atoms Mediate Inverse Morphochromism of an AIE Luminogen Angew. Chem. Int. Ed. 2020, 59, 8552. Multifunctional Au(I)-based AIEgens: Manipulating Molecular Structures and Boosting Specific Cancer Cell Imaging and Theranostics Angew. Chem. Int. Ed. 2020, 59, 7097. Achieving Efficient Multichannel Conductance in Through-Space Conjugated Single-Molecule Parallel Circuits Angew. Chem. Int. Ed. 2020, 59, 4581. Forster Resonance Energy Transfer: An Efficient Way to Develop Stimulus-Responsive Room-Temperature Phosphorescence Materials and Their Applications Matter 2020, 3, 449. Aggregation-Induced Emission Luminogens-Married 2D Black Phosphorus Nanosheets for Highly Efficient Multimodal Theranostics Adv. Mater. 2020, 32, 2003382. An All-Round Athlete on the Track of Phototheranostics: Subtly Regulate the Balance between Radiative and Non-Radiative Decays for Multimodal Imaging-Guided Synergistic Therapy Adv. Mater. 2020, 32, 2003210. Facile Synthesis of Efficient Luminogens with AIE Features for Three-Photon Fluorescence Imaging of the Brain through the Intact Skull Adv. Mater. 2020, 32, 2000364. Two Are Better than One: A Design Principle for Ultralong Persistent Luminescence of Pure Organics Adv. Mater. 2020, 32, 2001026. Biradical-Featured Stable Organic-Small-Molecule Photothermal Materials for Highly Efficient Solar-Driven Water Evaporation Adv. Mater. 2020, 32, 1908537. Bioinspired Simultaneous Changes in Fluorescence Color, Brightness and Shape of Hydrogels Enabled by AIEgens Adv. Mater. 2020, 32, 1906493. A Multifunctional Blue-Emitting Material Designed via Tuning Distribution of Hybridized Excited-State for High-Performance Blue and Host-Sensitized OLEDs Adv. Mater. 2020, 30, 2002323. Molecular Engineering to Boost AIE-Active Free Radical Photogenerators and Enable High-Performance Photodynamic Therapy under Hypoxia Adv. Funct. Mater. 2020, 30, 2002057. A Multifunctional Bipolar Luminogen with Delayed Fluorescence for High-Performance Monochromatic and Color-Stable Warm-White OLEDs Adv. Funct. Mater. 2020, 30, 2000019. Mechanistic Study on High Efficiency Deep Blue AIE-Based Organic Light-Emitting Diodes by Magneto-Electroluminescence Adv. Funct. Mater. 2020, 30, 1908704. Constitutional Isomerization Enables Bright NIR-II AIEgen for Brain-Inflammation Imaging Adv. Funct. Mater. 2020, 30, 1908125. Economic Sulfur Conversion to Functional Polythioamides Through Catalyst-free Multicomponent Polymerizations of Sulfur, Acids, and Amines J. Am. Chem. Soc. 2020, 142, 978. Time-Dependent Solid-State Molecular Motion and Colour Tuning of Host-Guest Systems by Organic Solvents Nature Commun. 2020, 11, 77. Multicolor Tunable Polymeric Nanoparticle from Tetraphenylethylene-Cage for Temperature Sensing in Living Cells J. Am. Chem. Soc. 2020, 142, 512. Red AIE-Active Fluorescent Probes with Tunable Organelle-Specific Targeting Adv. Funct. Mater. 2020, 30, 1909268. Identification and Single-Cell Analysis of Viable Circulating Tumor Cells by a Mitochondrion-Specific AIE Bioprobe Adv. Sci. 2020, 7, 1902760. Multifunctional Supramolecular Assemblies with Aggregation-Induced Emission (AIE) for Cell Line Identification, Cell Contamination Evaluation and Cancer Cell Discrimination ACS Nano 2020, 14, 7552. A “Simple” Donor-Acceptor AIEgen with Multi-Stimuli Responsive Behavior Mater. Horiz. 2020, 7, 135. Boosting the Photodynamic Therapy Efficiency by Using Stimuli-Responsive and AIE-featured Nanoparticles Biomaterials 2020, 232, 119749. Ultrafast Discrimination of Gram-Positive Bacteria and Highly Efficient Photodynamic Antibacterial Therapy Using Near-Infrared Photosensitizer with Aggregation-Induced Emission Characteristics Biomaterials 2020, 230, 119582. Selective Viable Cell Discrimination by a Conjugated Polymer Featuring Aggregation-Induced Emission Characteristic Biomaterials 2020, 230, 119658. Simultaneously Boosting Conjugation, Brightness and Solubility of Organic Fluorophore by AIEgen Chem. Sci. 2020, 11, 8438. Cancer Cell Discrimination and Dynamic Viability Monitoring through Wash-Free Bioimaging by AIEgens Chem. Sci. 2020, 11, 7676. Endowing TADF Luminophors with AIE Properties through Adjusting Flexible Dendrons for Highly Efficient Solution-Processed Nondoped OLEDs Chem. Sci. 2020, 11, 7194. pH-Responsive Au(I)-Disulfide Nanoparticles with Tunable Aggregation-Induced Emission for Monitoring Intragastric Acidity Chem. Sci. 2020, 11, 6472. Visualizing Semipermeability of Cell Membrane by a pH-responsive Ratiometric AIEgen Chem. Sci. 2020, 11, 5753. One Stone, Three Birds: One AIEgen with Three Colors for Fast Differentiating Three Pathogens Chem. Sci. 2020, 11, 4730. Fast Surface Immobilization of Native Proteins through CatalystFree Amino-Yne Click Bioconjugation Chem. Sci. 2020, 11, 3931. Type I Photosensitizers Based on Phosphindole Oxide for Photodynamic Therapy: Apoptosis and Autophagy Induced by Endoplasmic Reticulum Stress Chem. Sci. 2020, 11, 3405. Polymorph Selectivity of AIE Luminogen under Nano-Confinement to Visualize Polymer Microstructure Chem. Sci. 2020, 11, 997. Highly Stable and Bright AIE Dots for NIR-II Deciphering of Living Rats Nano Today 2020, 34, 100893. Targeted Theranostics for Tuberculosis: A Rifampicin-Loaded Aggregation-Induced Emission Carrier for Granulomas Tracking and Anti-Infection ACS Nano 2020, 14, 8046. Evoking Photothermy by Capturing Intramolecular Bond Stretching Vibration-Induced Dark-State Energy ACS Nano 2020, 14, 4265. Red AIE-Active Fluorescent Probes with Tunable Organelle-Specific Targeting Adv. Funct. Mater. 2020, 30, 1909268. Site-Selective, Multi-Step Functionalizations of CO2-Based Hyperbranched Poly(alkynoate)s Toward Functional Polymetric Materials Adv. Sci. 2020, 7, 2000465. Identification and Single-Cell Analysis of Viable Circulating Tumor Cells by a Mitochondrion-Specific AIE Bioprobe Adv. Sci. 2020, 7, 1902760. Efficient Near-Infrared Photosensitizer with Aggregation-Induced Emission for Imaging-Guided Photodynamic Therapy in Multiple Xenograft Tumor Models ACS Nano 2020, 14, 854. In Vivo Monitoring Tissue Regeneration by A Ratiometric Lysosomal AIE Probe Chem. Sci. 2020, 11, 3152. Highly Efficient Singlet Oxygen Generation, Two-Photon Photodynamic Therapy and Melanoma Ablation by Rationally Designed Mitochondria-Specific Near-Infrared AIEgens Chem. Sci. 2020, 11, 2494. Manipulating Solid-State Intramolecular Motion towards Controlled Fluorescence Patterns ACS Nano 2020, 14, 2090.