个人简介
邢祥友博士，深圳格拉布斯研究院副研究员，博士生导师，院长助理，深圳市海外高层次人才（孔雀计划C类）。
2012年获得北京大学有机化学博士学位，导师王智刚博士。博士期间主要从事不对称催化理论与手性催化剂设计领域的研究，攻克了Sharpless双羟化动力学拆分这一不对称催化领域的经典难题，实现了高效SAD动力学拆分，打破此前Sharpless双羟化不能进行动力学拆分的论断，并阐明了其详细的作用机制和设计原理。2013年10月进入加州理工学院B. M. Stoltz课题组进行C-H键氧化的工作。2014年10月起加入Grubbs课题组，从事被誉为人类催化界十大挑战之一的“惰性烯烃反马氏水化”研究，发展了系列新型铂催化剂，实现了氰基和氰醇的高效水化，为反马氏烯烃水化的研究奠定了的基础。
2017年9月回国加入南方科技大学，历任研究助理教授、研究副教授，同时担任深圳格拉布斯研究院院长助理一职，全面参与研究院的各项筹建工作。从事不对称催化理论，催化剂的理性设计与应用领域的独立研究，已先后开发了“手性经济性”不对称转移氢化催化体系和手性烯烃复分解催化体系。
研究领域
1. 不对称催化与有机合成
2. 螺旋电子理论
3. 高分子合成(ROMP)
课题组以螺旋电子理论为基础，力求通过手性配体和手性催化剂的精准设计，高效实现相关手性催化过程；详细研究这些转化中手性传递和手性识别的机制和相应的递导规律，阐明官能团电子极化率与手性选择性之间的本质关系，并通过发展的不对称催化体系进行有机小分子的合成研究和高分子合成研究。
近期论文
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Shaofeng Li, † Shijie Feng, † Yali Zhou, Chao Liu，Bo Chen,* and Xiangyou Xing* Development of Highly Enantio- and Z‑Selective Grubbs Catalysts via Controllable C−H Bond Activation. J. Am. Chem. Soc. 2023, XX, XXX–XXX. https://doi.org/10.1021/jacs.3c08420
Xingjun Xu †, Yipeng You †, Ming Yu Jin †, Fan-Jie Meng, Chen Xu* and Xiangyou Xing* Pincer Ru with a single stereogenic identity for highly efficient asymmetric transfer hydrogenation of ketones. Science China Chemistry 2023, 66(5), 1443–1449. https://doi.org/10.1007/s11426-022-1535-7
Dongxu He, Chen Xu,* and Xiangyou Xing* Developing Ru-Catalysts for Asymmetric Transfer Hydrogenation of Acyclic Imines. Org. Lett. 2022, 24(45), 8354–8358. https://doi.org/10.1021/acs.orglett.2c03385
Fumin Chen, Ming Yu Jin, David Zhigang Wang, Chen Xu,* Jianchun Wang,* and Xiangyou Xing* Simultaneous Access to Two Enantio-enriched Alcohols by a Single Ru-Catalyst: Asymmetric Hydrogen Transfer from Racemic Alcohols to Matching Ketones. ACS Catal. 2022,12(22),14429–14435. https://doi.org/10.1021/acscatal.2c04657
Ming Yu Jin+, Yali Zhou+, Dengmengfei Xiao+, Yipeng You, Qianqian Zhen, Guanyu Tao, Peiyuan Yu* and Xiangyou Xing* Simultaneous Kinetic Resolution and Asymmetric Induction within a Borrowing Hydrogen Cascade Mediated by a Single Catalyst. Angew. Chem. Int. Ed. 2022, 61(3), e202112993. https://onlinelibrary.wiley.com/doi/10.1002/anie.202112993
Yipeng You †, Ming Yu Jin †, Guanyu Tao and Xiangyou Xing * Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer. Molecules 2021, 26(24), 7475. https://doi.org/10.3390/molecules26247475
Chengcheng Li, Xiao-Yong Chang, Luqiong Huo, Haibo Tan, Xiangyou Xing*, and Chen Xu* Hydration of Cyanohydrins by Highly Active Cationic Pt Catalysts: Mechanism and Scope. ACS Catal. 2021, 11(14), 8716–8726. https://pubs.acs.org/doi/10.1021/acscatal.1c02254
Yali Zhou, Xingjun Xu, Hongwei Sun, Guanyu Tao, Xiao-Yong Chang, Xiangyou Xing*, Bo Chen* and Chen Xu* Development of highly efficient platinum catalysts for hydroalkoxylation and hydroamination of unactivated alkenes. Nat. Commun. 2021, 12(1), 1953. https://www.nature.com/articles/s41467-021-22287-w
Dongxu He, Xingjun Xu, Yi Lu, Min-Jie Zhou*, and Xiangyou Xing* Asymmetric Transfer Hydrogenation of Densely Functionalized Diheteroaryl and Diaryl Ketones by a Ru-Catalyst of Minimal Stereogenicity. Org. Lett. 2020, 22(21), 8458–8463. https://pubs.acs.org/doi/10.1021/acs.orglett.0c03064
Yupeng Pan, Yipeng You, Dongxu He, Fumin Chen, Xiaoyong Chang, Ming Yu Jin*, and Xiangyou Xing* Asymmetric Synthesis of gamma-Secondary Amino Alcohols via a Borrowing-Hydrogen Cascade. Org. Lett. 2020, 22(18), 7278–7283. https://pubs.acs.org/doi/10.1021/acs.orglett.0c02614
Fumin Chen, Dongxu He, Li Chen, Xiaoyong Chang, David Zhigang Wang, Chen Xu*, and Xiangyou Xing* Chirality-Economy Catalysis: Asymmetric Transfer Hydrogenation of Ketones by Ru-Catalysts of Minimal Stereogenicity. ACS Catal. 2019, 9(6), 5562–5566. https://pubs.acs.org/doi/10.1021/acscatal.9b01535
Xiangyou Xing, Chen Xu, Bo Chen, Chengcheng Li, Scott C. Virgil*, and Robert H. Grubbs* Highly Active Platinum Catalysts for Nitrile and Cyanohydrin Hydration: Catalyst Design and Ligand Screening via High-Throughput Techniques. J. Am. Chem. Soc. 2018, 140(50), 17782–17789. https://pubs.acs.org/doi/10.1021/jacs.8b11667
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