个人简介
Dr. Ping Song is the Associate Professor of the Department of Biomedical Engineering at Shanghai Jiao Tong University. Dr. Song received her Ph.D. degree from Shanghai Institute of Applied Physics in Chinese academy of sciences. Then Dr. Song worked in Rice University as a postdoctoral researcher for one year and then was promoted to be a senior research scientist for four years. At the same time, Dr. Song part-time worked in NuProbe Inc as a senior research scientist and took charge in multiple projects. Dr. Song’s interesting research areas including: 1) cancer diagnosis and monitoring using PCR/qPCR/next generation sequencing/third generation sequencing; 2) early cancer detection based on biosensors; 3) DNA data storage. She has published many papers in top journals like Nature Biomedical Engineering, Nature Communications, Nature Protocols, Cancer Discovery, Nano Letters et al. In addition, Dr. Song focuses on commercialization of scientific and research findings. She has many Chinese patents, American patents, and international patents and some of the patents were licensed to company to be developed as kits.
Education background
2006 – 2010 Bachelor - Yantai University
2010 – 2013 Master - Shanghai Normal University
2013 – 2016 Ph.D. – Shanghai Institute of Applied Physics, Chinese Academy of Sciences
Work Experience
2016 – 2017, Postdoc, Department of Biomedical Engineering, Rice University
2017 – 2021, Senior Research Scientist, Department of Biomedical Engineering, Rice University
2019 – 2021, Senior Research Scientist (part-time), NuProbe Inc
研究领域
1) Cancer diagnosis and monitoring using PCR/qPCR/Next Generation Sequencing/Third Generation Sequencing
2) Early cancer detection based on biosensors
3) DNA data storage
近期论文
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Yi Wu#, Dr. Jinxiao Guo#, Wenjun Li, Xuehao Xiu, Deepak Thirunavukarasu, Dr. Yudong Wang, Prof. Kai Wang, Dr. Weiyu Chen, Prof. David Yu Zhang, Prof. Xiurong Yang, Prof. Chunhai Fan, Prof. Ping Song*. Extended Enrichment for Ultrasensitive Detection of Low-Frequency Mutations by Long Blocker Displacement Amplification. Angew Chem Int Ed 2024.
Yunpei Si#, Xiawen Wang#, Xinglei Su#, Zhi Wong, Qiongzheng Hu, Qian Li, Chunhai Fan, David Yu Zhang, Yunshan Wang, Shihua Luo, Ping Song*. Extended Enrichment for Ultrasensitive Detection of Low-Frequency Mutations by Long Blocker Displacement Amplification. Angew Chem Int Ed 2024.
Ping Song*, Chunhai Fan*. Selecting aptamers with programmed affinities. Nature Chemistry 2023.
Haipei Zhao, Xuehao Xiu, Mingqiang Li, Shaobo Dai, Mingyang Gou, Leyang Tao, Xiaolei Zuo*, Chunhai Fan, Zhongqun Tian, Ping Song*. Programming super DNA-enzyme molecules for on-demand enzyme activity modulation. Angew Chem Int Ed 2023.
Nina G Xie#, Michael X Wang#, Ping Song, Shiqi Mao, Yifan Wang, Yuxia Yang, Junfeng Luo, Shengxiang Ren*, David Yu Zhang*. Designing highly multiplex PCR primer sets with Simulated Annealing Design using Dimer Likelihood Estimation (SADDLE). Nature Communications 13, 1881, 2022.
Ping Song#, Lucia Ruojia Wu#, Yan Helen Yan, Jinny X. Zhang, Tianqing Chu, Lawrence N. Kwong, Abhijit A. Patel, and David Yu Zhang*. Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics. Nature Biomedical Engineering 1-14, 2022.
Ping Song, Sherry X. Chen, Yan Helen Yan, Alessandro Pinto, Lauren Y. Cheng, Peng Dai, Abhijit A. Patel, and David Yu Zhang*. Selective multiplexed enrichment for the detection and quantitation of low-fraction DNA variants via low-depth sequencing. Nature Biomedical Engineering 690-701, 2021.
Dekai Ye#, Min Li#, Tingting Zhai#, Ping Song#…Xiaolei Zuo*, Chunhai Fan*. Encapsulating living tumor cells with hybridization chain reaction. Nature Protocols 15(7), 2163-2185, 2020.
Ping Song#, Juwen Shen#, Dekai Ye#, Baijun Dong#… Xiaolei Zuo*, Chunhai Fan*. Programming bulk enzyme heterojunctions for biosensor development with tetrahedral DNA framework. Nature Communications 11, 838, 2020.
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