个人简介
林俐,长聘教轨助理教授，博士生导师，上海市教委“晨光计划”学者。于2013年和2018年在上海交通大学生物医学工程学院获得学士和博士学位；之后分别在上海交大和伊利诺伊大学香槟分校（UIUC，师从Shuming Nie教授）开展博士后研究。曾获SERS国际会议最佳墙报奖、IMCO2019国际会议最佳论文奖（Best paper award）等。在Nano Letters, ACS Nano, Nature Commuminations，Small Methods等期刊上发表高水平论文，被引600余次，担任多个SCI期刊的审稿人，现承担或参与多项国家自然基金项目、省部级和校级项目以及横向课题的研究。博士期间作为早期主要研发人开发新型拉曼光谱纳米探针GERTs，并作为技术顾问帮助实现大规模生产，有望作为首个拉曼显影示踪剂进入临床转化阶段。
近年来的研究兴趣集中于基于光学方法的无创病灶定位和检测，包括近红外二区拉曼响应纳米探针的设计开发、深穿透拉曼光谱技术、拉曼图像重建和术中活体定位病灶。
欢迎生医工、光学、化学、材料和光谱学领域的硕士、博士以及博士后加入课题组！同时，欢迎对科研感兴趣的本科生提前加入实验室。近年来已多次指导本科生毕业设计、大创、PRP等项目，并指导学生参与“挑战杯”科创竞赛获省部级奖励。可通过Email 直接与我联系。
科研项目
1. 国家自然科学基金青年项目，课题负责人，2019-2022
“近红外二区增强拉曼探针及其组织穿透深度研究”
2.上海交通大学医工交叉研究基金青年项目，合作方负责人，2022-2024
“基于机器学习算法和光纤拉曼光谱系统的胃癌快速诊断研究”
3.上海市科委“科技创新行动计划”高新技术领域项目，子课题负责人，2021-2023
4. 上海市教委“晨光计划”，课题负责人，2022-2023
研究领域
基于深穿透光谱技术的小动物活体无创光学成像
基于拉曼光谱的胃癌的快速诊断及预后分析
近红外二区表面增强拉曼光谱探针的设计和开发
近期论文
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Featued Articles After 2021
1. Zongyu Wu, Binge Deng, Yutong Zhou, Haoqiang Xie, Yumin Zhang, Li Lin*, Jian Ye*. Non-invasive detection, precise localization, and perioperative navigation of in vivo deep lesions using transmission Raman spectroscopy. Advanced Science. In press. (IF=17.2)
2. Yumin Zhang, Li Lin*, Jian Ye*. A rapid and universal method for depth estimation of lesions in heterogeneous tissues via photosafe ratiometric transmission Raman spectroscopy. View, 2023, 20230022.
3. Yumin Zhang, Ruoyu Chen, Fugang Liu, Peng Miao, Li Lin*, and Jian Ye*. In Vivo Surface-Enhanced Transmission Raman Spectroscopy under Maximum Permissible Exposure: Toward Photosafe Detection of Deep-Seated Tumors. Small Methods, 2023, 7(2), 2201334. (IF=15.2)
4. Li Lin, Ruiyang Xue, Shuming Nie. "Surface-enhanced Raman scattering (SERS) nanoparticles for biodiagnostics, bioimaging, and spectroscopy-guided cancer surgery", In: Reference Module in Materials Science and Materials Engineering, Elsevier, 2022. (Invited Book Chapter)
5. Haoqi He, Yumin Zhang, Shuo Zhu, Jian Ye*, and Li Lin*. "Resonant strategy in designing NIR-II SERS nanotags: a quantitative study." The Journal of Physical Chemistry C, 2022, 126, 12575. (IF=4.2)
6. Yao Lu, Li Lin*, Jian Ye*, “Human metabolite detection by surface-enhanced Raman spectroscopy”, Materials Today Bio, 2022, 13, 100205. (IF=10.5)
7. Li Lin, Jian Ye, “Spontaneous Raman and Surface-Enhanced Raman Scattering Bioimaging.” In: Wei X., Gu B. (eds) Optical imaging in Human Disease and Biological Research. Advances in Experimental Medicine and Biology, vol 3233. Springer, Singapore, 2021, pp177-195. (Invited Book Chapter)
Featured Articles Before 2021
1. Yuqing Gu, Chang He, Yuqing Zhang, Li Lin, Benjamin David Thackray, Jian Ye*, “Gap-enhanced Raman tags for physically unclonable anticounterfeiting labels”, Nature Communications, 2020, 11, 516. (IF=13.8)
2. Li Lin, Qiang Zhang, Xiyao Li, Meng Qiu, Xin Jiang, Hongchen Gu*, Dang Yuan Lei*, Jian Ye*, “Electron Transfer in Plasmonic Nanogaps Interrogated with Surface-Enhanced Raman Scattering,” ACS Nano, 2018, 12, 6492. (IF=15.8)
3. Li Lin, Zhonghui Liu, Xiyao Li, Hongchen Gu, Jian Ye*, “Quantifying the Reflective Index of Nanometer-Thick Molecular Layers on Nanoparticle,” Nanoscale, 2017, 9, 2213. (IF=7.2)
4. Li Lin, Mario Zapata, Min Xiong, Zhonghui Liu, Shanshan Wang, Hong Xu, Andrei G. Borisov, Hongchen Gu, Peter Nordlander*, Javier Aizpurua*, Jian Ye*, “Nanooptics of Plasmonic Nanomatryoshkas: Shrinking the Size of a Core–Shell junction to Subnanometer,” Nano Letters, 2015, 15, 6419. (IF=11.1)
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