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学习/工作经历: 1987-1991:中国海洋大学,海水养殖专业,农学学士 1995-1999:中国海洋大学,水产养殖专业,硕士 2001-2005:中国海洋大学,水产养殖专业,博士 1991.7~至今:中国海洋大学,水产学院,讲师、副教授、教授 2011-2012:美国加州大学Davis分校,兽医学院,访问学者 授课: 本科生《生物实验技术》理论课和实验课、研究生《病理学与病理学技术》。 主持/参加课题: 1.国家自然科学基金项目“牙鲆多聚免疫球蛋白受体(pIgR)在黏膜免疫球蛋白转运过程中的作用(31472295)”(2015.1-2018.12)88万 2.国家自然科学基金项目“鱼类淋巴囊肿病毒受体的鉴定与特性分析(31072232)”(2011.1-2013.12)35万 3.国家科技支撑计划项目“海洋水产病害实用化检测及预警技术的建立与应用(2012BAD17B01)”子课题(2012.1-2015.12)150万 4.农业公益性行业科研专项经费项目“养殖虾类病毒病快速诊断与生物防控技术的研究及示范(201103034)”子课题(2012.1-2015.12)110万 5.山东省科技发展计划项目“主要海水养殖动物重要疾病免疫快速诊断技术的开发与应用(2014GNC111015)”(2014.1-2016.12)20万 6.天津市成果转化项目“免疫芯片技术在水产养殖动物高通量诊断中的应用”(231304060)(2013.1.-2016.12)30万 授权专利: 1.绳秀珍,徐晓丽,战文斌.鱼类淋巴囊肿病毒免疫检测芯片及其制备方法与应用授权号:ZL201080002349.9 2.绳秀珍,徐晓丽,战文斌.对虾白斑症病毒免疫检测芯片及其制备方法与应用授权号:ZL 200910017831.9

研究领域

水产动物病害与免疫学

近期论文

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1.Ronghua Wu, Xiuzhen Sheng*, Xiaoqian Tang, Jing Xing and Wenbin Zhan Transcriptome Analysis of Flounder (Paralichthys olivaceus) Gill in Response to Lymphocystis Disease Virus (LCDV) Infection: Novel Insights into Fish Defense Mechanisms. Int. J. Mol. Sci. 2018, 19:160 2.Zhong Y; Fei CJ; Tang XQ; Zhan WB; Sheng XZ*. A 32 kDa viral attachment protein of lymphocystis disease virus (LCDV) specifically interacts with a 27.8 kDa cellular receptor from flounder (Paralichthys olivaceus).J Gen Virol; 2017,98(6):1477-1488 3.YangDu, Xiaoqian Tang, Wenbin Zhan, Jing Xing,Xiuzhen Sheng*.Immunoglobulin Tau Heavy Chain (IgT) in Flounder, Paralichthys olivaceus: Molecular Cloning, Characterization, and Expression Analyses.Int. J. Mol. Sci,2016, 17, 1571 4.Ronghua Wu, Xiaoqian Tang, Xiuzhen Sheng*, Wenbin Zhan. Relationship between expression of cellular receptr-27.8kDa and lymphocystis disease virus (LCDV) infection. PLoS ONE 2015,10(5): e0127940. 5.R.-H. Wu, X.-Q. Tang, X.-Z. Sheng*,W.-B. Zhan.Tissue Distribution of the 27.8 kDa Receptor and Its Dynamic Expression in Response to Lymphocystis Disease Virus Infection in Flounder (Paralichthys olivaceus), Journal of Comparative Pathology, 2015, Vol. 153, 324-332 6.Sheng, X.Z; Wu, R.H; Tang, X.Q; Xing, J.; Zhan, W.B.Tissue Localization of Lymphocystis Disease Virus (LCDV) Receptor-27.8 kDa and Its Expression Kinetics Induced by the Viral Infection in Turbot (Scophthalmusmaximus). Int. J. Mol. Sci.2015, 16, 26506-26519 7.Xiuzhen Sheng, Xiaoli Xu, Wenbin Zhan. Development and Application of Antibody Microarray for Lymphocystis Disease Virus Detection in Fish.Journal of Virological Methods,2013,189:243-249 8.Guojing Xu, Wenbin Zhan, Bingjie Ding, Xiuzhen Sheng*. Molecular cloning and expression analysis of polymeric immunoglobulin receptor in flounder (Paralichthys olivaceus). Fish and Shellfish Immunology, 2013,35: 653-660 9.Xiuzhen Sheng,Guojing Xu, Xiaoqian Tang, Wenbin Zhan*. Monoclonal antibodies recognizing mucus immunoglobulin and surface immunoglobulin-positive cells of flounder (Paralichthys olivaceus). Veterinary Immunology and Immunopathology, 2012, 145: 143-150 10.Sheng XZ, Wang M, Xing J, Zhan WB*. Monoclonal antibodies against 27.8 kDa protein receptor efficiently block lymphocystis disease virus infection in flounder (Paralichthys olivaceus) gill cells. Diseases of Aquatic Organisms. 2012, 100: 19-27. 11.Xiaoqian Tang, Jing Diao, Wenbin Zhan, Xiuzhen Sheng*. Identification of a 37.6 kDa membrane protein from flounder gill cells involved in binding and infection to lymphocystis disease virus. Aquaculture, 2012(358-359): 132-138 12.Xiuzhen Sheng, Jialei Song, Wenbin Zhan*. Development of a colloidal gold immunochromatographic test strip for detection of lymphocystis disease virus in fish. Journal of Applied microbiology. 2012,113:737-744 13.Mu Wang, Xiuzhen Sheng*, Jing Xing, Wenbin Zhan. Identification of a 27.8 kDa protein from flounder gill cells involvedin lymphocystis disease virus binding and infection. Diseases of Aquatic Organisms, 2011, 94(1): 9-16. 14.Guojing Xu, Xiuzhen Sheng*, Jing Xing, Wenbin Zhan. Effect of temperature on immune response of Japanese flounder (Paralichthys olivaceus) to inactivated lymphocystis disease virus (LCDV). Fish Shell.Immunol. 2011, 30(2): 525-531.

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