叶健文 - 华南理工大学 - 生物医学科学与工程学院

个人简介

教育经历 2013.09-2018.07 清华大学生命科学学院，理学博士学位 2009.09-2013.07 华南理工大学化学与化工学院，工学学士学位工作经历 2021.04-至今华南理工大学生物科学与工程学院，副教授 2020.08-2021.04 中国科学院深圳先进技术研究院，副研究员 2018.07-2020.07 清华大学生命科学院，博士后

研究领域

合成生物学, 细胞工厂设计与改造, 代谢工程, 生物过程优化及放大, 生物材料, 下一代工业生物技术

近期论文

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Li Mengyi, Ma Yueyuan, Zhang Xu, Zhang Lizhan, Chen Xinyu, Ye Jian-Wen#, Chen Guo-Qiang#, (2021) Tailor-made polyhydroxyalkanoates by reconstructing Pseudomonas entomophila, Advanced Materials. Accepted. (JCR1区，IF=30.849) Wang Xuan*, Han Jia-Ning*, Zhang Xu, Ma Yue-Yuan, Lin Yi-Na, Wang Huan, Li Dian-Jie, Zheng Tao-Ran, Wu Fu-Qing, Ye Jian-Wen#, Chen Guo-Qiang#, (2021) Reversible thermal regulation for bifunctional dynamic control of gene expression in Escherichia coli, Nature Communications, 12, 1411. (JCR1区，IF=14.919) Ye Jian-Wen, Chen Guo-Qiang#. (2021), Halomonas as a chassis, Essays in Biochemistry, 00, 1-11. (JCR1区，IF=8) Lin Yina, Guan Yuying, Dong Xu, Ma Yueyuan, Wang Xuan, Leng Yuchen, Wu Fuqing, Ye Jian-Wen#, Chen Guo-Qiang#; (2021) Engineering Halomonas bluephagenesis as a chassis for bioproduction from starch, Metabolic Engineering, 64,134-145. (JCR1区，IF=9.783) Ma Hong*, Zhao Yiqing*, Huang Wuzhe, Zhang Lizhan, Wu Fuqing, Ye, Jian-Wen#, Chen Guo-Qiang#. (2020). Rational flux-tuning of Halomonas bluephagenesis for coproduction of bioplastic PHB and ectoine. Nature Communications. 11, 3313. (JCR1区，IF=14.919) Du Hetong*, Zhao Yiqing*, Wu Fuqing, Ouyang Pengfei, Chen Jinchun, Jiang Xiaoran#, Ye Jian-Wen#, Chen Guo-Qiang#. (2020) Engineering Halomonas bluephagenesis for L-threonine production. Metabolic Engineering. 60, 119-127. (JCR1区，IF=9.783) Ye Jian-Wen, Hu Dingkai, Yin Jin, Huang Wuzhe, Xiang Ruijuan, Zhang Lizhan, Wang Xuan, Han Jianing, Chen Guo-Qiang. (2020). Stimulus response-based fine-tuning of polyhydroalkanoate pathway in Halomonas. Metabolic Engineering, 57, 85-95. (JCR1区，IF=9.783) Chen Yong, Chen Xinyu, Du Hetong, Zhang Xu, Ma Yiming, Chen Jin, Ye Jian-Wen#, Jiang Xiaoran#, Chen Guo-Qiang#. (2019). Chromosome engineering of the TCA cycle in Halomonas bluephagenesis for production of copolymers of 3-hydroxybutyrate and 3-hydroxyvalerate (PHBV). Metabolic Engineering. 54, 69-82. (JCR1区，IF=9.783) Ye Jian-Wen*, Hu Dingkai*, Che Xuemei, Jiang Xiaoran, Li Teng, Chen Jinchun, Zhang Haoqian#, Chen Guo-Qiang#. (2018). Engineering of Halomonas bluephagenesis for low cost production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from glucose. Metabolic Engineering, 47, 143-152. (JCR1区，IF=9.783) Ye Jian-Wen*, Huang Wuzhe*, Wang Dongsheng*, Chen Fengyi, Yin Jin, Li Teng, Zhang Haoqian, Chen Guo-Qiang#. (2018). Pilot scale-up of poly(3- hydroxybutyrate-co-4- hydroxybutyrate) production by Halomonas bluephagenesis via cell growth optimization process. Biotechnology Journal, 13, 1800074. (Q1区，IF=4.677) Shen Rui*, Yin Jin*, Ye Jian-Wen*, Xiang Ruijuan, Ning Zhiyu, Huang Wuzhe, Chen Guo-Qiang#. (2018) Promoter engineering for enhanced P(3HB-co-4HB) production by Halomonas bluephagenesis. ACS Synthetic Biology. 7, 1897-1906. (JCR1区，IF=5.11) Chen Xiangbin*, Yin Jin*, Ye, YeJian-Wen*, Zhang Haoqian, Che Xuemei, Ma Yiming, Li Mengyi, Wu Linping, Chen Guo-Qiang#. (2017). Engineering Halomonas bluephagenesis TD01 for non-sterile production of poly(3-hydroxybutyrate-co-4hydrobutyrate). Bioresource Technology, 244, 534-541. (JCR1区，IF=9.642) Zhao Liang, Ye Jian-Wen, Fu Jing, Chen Guo-Qiang#. Engineering peptidoglycan degradation related genes of Bacillus subtilis for better fermentation processes. (2017). Bioresource Technology, 248, 238-247. (JCR1区，IF=9.642) Li Teng*, Ye Jian-Wen*, Shen Rui, Zong Yeqing, Zhao Xuejin, Lou Chunbo, Chen Guo-Qiang#. (2016). Semi-rational approach for ultra-high poly(3-hydroxybutyrate) accumulation in Escherichia coli by combining one-step library construction and high-throughput screening. ACS Synthetic Biology, 5, 1308-1317. (JCR1区，IF=5.11) Chen Guo-Qiang#, Ivan Hajnal, Wu Hong, Lv Li, Ye Jian-Wen. Engineering biosynthesis mechanisms for diversifying polyhydroxyalkanoates. (2015). Trends in Biotechnology, 33, 565-574. (JCR1区，IF=19.536)