賴品光 - 中央研究院原子与分子科学研究所 -

个人简介

學歷 2003-2010 加拿大英屬哥倫比亞大學細胞與發育生物學博士 1999-2003 加拿大英屬哥倫比亞大學生物細胞與遺傳學學士經歷 2015-2017 國立清華大學生物醫學工程研究所，助理教授 2015-2015 中央研究院原子與分子科學研究所，訪問學者 2014-2015 麻省總醫院神經科，助理研究員 2014-2015 哈佛大學醫學院神經科學研究所，講師 2010-2014 哈佛大學醫學院神經科學研究所，博士後研究 2010-2014 麻省總醫院神經科，博士後研究榮譽及獎項 2015-present Ministry of Science and Technology Salary Bonus for Recruitment of Outstanding Faculties and Scholars, Ministry of Science and Technology, Taiwan 2015 Partners in Excellence (Teamwork), Massachusetts General Hospital, USA 2013 Excellence in Research, American Society for Gene and Cell Therapy, USA 2013 Travel Award, American Society for Gene and Cell Therapy, USA 2013 Young Investigator Award, International Society for Extracellular Vesicles, USA 2012 3rd Place, Best Poster Award, MGH Poster Day Celebration, USA 2011-2014 Postdoctoral Fellowship, Canadian Institute of Health Research (CIHR), Canada 研究成果 A multiplexed bioluminescent reporter for sensitive and non-invasive tracking of DNA double strand break repair dynamics in vitro and in vivo Multiresolution Imaging Using Bioluminescence Resonance Energy Transfer Identifies Distinct Biodistribution Profiles of Extracellular Vesicles and Exomeres with Redirected Tropism

研究领域

分子影像細胞間通訊基因工程奈米生物工程

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Pucci, F., Garris, C., Lai, C.P., Newton, A., Pfirschke, C., Engblom, C., Alvarez, D., Sprachman, M., Evavold, C., Magnuson, A., von Andrian, U.H., Glatz, K., Breakefield, X.O., Mempel, T.R., Weissleder, R., Pittet, M.J. (2016). SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science, 352 (6282): 242-6. Lai, C.P., Kim, K.Y., Badr, C.E., Mempel, T.R., Tannous, B.A., Breakefield, X.O. (2015). Visualization and tracking of tumor extracellular vesicles delivery and RNA translation using multiplexed reporters. Nature Communications, 6: 7029.1. Zaborowski, M., Breakefield, X.O., Lai, C.P. (2015). Extracellular vesicles: composition, biological relevance and methods of study. Bioscience, 65 (8): 783-797. Lai, C.P., Mardini, O., Ericsson, M., Prabhaker, S., Maguire A., Chen, J.W., Tannous, B.A., Breakefield, X.O. (2014). Dynamic biodistribution of extracellular vesicles in vivo using a multimodal reporter. ACS Nano, 8 (1): 483-94. Lai, C.P., Breakefield, X.O., (2012). Role of exosomes/microvesicles in the nervous system and use in emerging therapies. Frontiers in Physiology, (3): Article 228. Lai, C.P., Bechberger, J., Naus, C. (2009). Pannexin2 as a Novel Negative Growth Regulator in C6 Gliomas. Oncogene, 28 (49): 4402-8. Lai, C.P., Bechberger, J., Thompson, R.J., MacVicar, B., Bruzzone, R., Naus, C. (2007). Tumor-suppressive Effects of Pannexin1 in C6 Gliomas. Cancer Research, 67 (4): 1545-54.