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李青 副研究员 收藏 完善纠错
中国科学院烟台海岸带研究所   
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个人简介

研究内容 主要从事多糖的化学修饰、高活性多糖衍生物的制备及相关生物活性的测试。 教育背景 2005-09_2011-07 大连理工大学 博士 工作经历 2011-07_2019-09 中国科学院烟台海岸带研究所 生物资源 助理研究员 2019-10_今 中国科学院烟台海岸带研究所 生物资源 副研究员 研究项目 2013-01_2015-12 壳聚糖氨基正电性与抑菌活性 专利 [1] 郭占勇,谭文强,李青,等. 一种季膦化壳聚糖季铵盐及其制备方法和应用. 2016-12-23. [2] 郭占勇,谭文强,李青,等. 一种苄基三唑鎓盐淀粉及其制备方法和应用. 2016-12-23. [3] 郭占勇,谭文强,李青,等. 一种含烟酰胺基的碘代甲基三氮唑淀粉及其制备方法和应用. 2016-05-05. [4] 郭占勇,谭文强,董方,等. 一种乙酰化淀粉季膦盐及其制备方法和应用. 2016-05-05. [5] 郭占勇,张晶晶,谭文强,等. 一种苯甲醛席夫碱类氨基吡啶乙酰化淀粉及其制备方法. 2015-11-04. [6] 郭占勇,谭文强,张晶晶,等. 一种1,2,3-三氮唑类淀粉衍生物及其制备方法和应用. 2015-07-16. [7] 郭占勇,周婷婷,董方,等. 一种6-氨基-6-脱氧麦芽糖及其制备和应用. 2015-06-17. [8] 郭占勇,周婷婷,董方,等. 一种6-氨基-6-脱氧海藻糖及其制备和应用. 2015-06-17. [9] 郭占勇,谭文强,王刚,等. 一种1,2,3-三氮唑类淀粉衍生物及其制备方法. 2015-06-17. [10] 郭占勇,周婷婷,董方,等. 一种6-氨基-6-脱氧纤维二糖及其制备和应用. 2015-06-17. [11] 郭占勇,李青,董方,等. 一种含三氮唑的壳聚糖季铵盐及其制备和应用. 2014-05-22. [12] 董方,郭占勇,李青,等. 一种壳聚糖双吡啶季铵盐及其制备方法和应用. 2014-05-14. [13] 郭占勇,胡云霞,王刚,等. 一种氨基吡啶类乙酰菊糖及其制备方法. 2014-01-02. [14] 郭占勇,胡云霞,王刚,等. 一种含1,2,3-三氮唑的菊糖衍生物及其制备方法. 2014-01-02. [15] 王刚,董方,李青,等. 一种硫酸酯化壳聚糖季铵盐及其制备和应用. 2013-09-26. [16] 郭占勇,任剑明,胡云霞,等. 一种两亲性c-6-(4-(甲基氨基)-1,2,3-三氮唑)脱氧菊糖衍生物及其制备和应用. 2013-04-28. [17] 郭占勇,任剑明,董方,等. 一种两亲性氨基菊糖及其制备. 2012-11-06. [18] 郭占勇,任剑明,周婷,等. 一种壳聚糖硫酸酯希夫碱及其合成方法. 2012-09-21. [19] 郭占勇,任剑明,董方,等. 一种6-氨基-6-脱氧甲壳素及其制备. 2012-09-21.

研究领域

多糖化学修饰

近期论文

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[1] Tan, Wenqiang,Zhang, Jingjing,Mi, Yingqi,Dong, Fang,Li, Qing,&Guo, Zhanyong.(2020).Enhanced antifungal activity of novel cationic chitosan derivative bearing triphenylphosphonium salt via azide-alkyne click reaction.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,165,1765-1772. [2] Sun, Xueqi.,Zhang, Jingjing.,Mi, Yingqi.,Chen, Yuan.,Tan, Wenqiang.,...&Guo, Zhanyong.(2020).Synthesis, characterization, and the antioxidant activity of the acetylated chitosan derivatives containing sulfonium salts.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,152,349-358. [3] Zhang, JJ.,Sun, XQ.,Chen, Y.,Mi, YQ.,Tan, WQ.,...&Guo, ZY.(2020).Preparation of 2,6-diurea-chitosan oligosaccharide derivatives for efficient antifungal and antioxidant activities.CARBOHYDRATE POLYMERS,234,115903. [4] Ma, XX.,Liu, SJ.,Liu, Y.,Li, XQ.,Li, Q.,...&Xia, CH.(2020).Promoted liquid-phase hydrodechlorination of chlorophenol over Raney Ni via controlling base: Performance, mechanism, and application.CHEMOSPHERE,242,UNSP 125202. [5] Tan, Wenqiang,Zhang, Jingjing,Zhao, Xiang,Li, Qing,Dong, Fang,&Guo, Zhanyong.(2020).Preparation and physicochemical properties of antioxidant chitosan ascorbate/methylcellulose composite films.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,146,53-61. [6] Zhang, Jingjing,Tan, Wenqiang,Li, Qing,Dong, Fang,&Guo, Zhanyong.(2020).Synthesis and Characterization of N,N,N-trimethyl-O-(ureidopyridinium)acetyl Chitosan Derivatives with Antioxidant and Antifungal Activities.MARINE DRUGS,18(3),163. [7] Chen, Y,Mi, YQ,Li, Q,Dong, F,&Guo, ZY.(2020).Synthesis of Schiff bases modified inulin derivatives for potential antifungal and antioxidant applications.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,143,714-723. [8] Chen, Yuan.,Liu, Xiguang.,Sun, Xueqi.,Zhang, Jingjing.,Mi, Yingqi.,...&Guo, Zhanyong.(2020).Synthesis and Antioxidant Activity of Cationic 1,2,3-Triazole Functionalized Starch Derivatives.POLYMERS,12(1),112. [9] Zhang, JJ.,Mi, YQ.,Sun, XQ.,Chen, Y.,Miao, Q.,...&Guo, ZY.(2020).Improved Antioxidant and Antifungal Activity of Chitosan Derivatives Bearing Urea Groups.STARCH-STARKE,72(5-6),1900205. [10] Wei, LJ,Tan, WQ,Wang, G,Li, Q,Dong, F,&Guo, ZY.(2019).The antioxidant and antifungal activity of chitosan derivatives bearing Schiff bases and quaternary ammonium salts.CARBOHYDRATE POLYMERS,226,UNSP 115256. [11] Zhang, JJ.,Mi, YQ.,Sun, XQ.,Chen, Y.,Gu, GD.,...&Guo, ZY.(2019).Preparation of starch derivatives bearing urea groups and the evaluation of antioxidant, antifungal, and antibacterial activities.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,141,1271-1279. [12] Sun, XQ.,Zhang, JJ.,Chen, Y.,Mi, YQ.,Tan, WQ.,...&Guo, ZY.(2019).Synthesis, Characterization, and the Antioxidant Activity of Carboxymethyl Chitosan Derivatives Containing Thiourea Salts.POLYMERS,11(11),1810. [13] Zhang, JJ.,Tan, WQ.,Wei, LJ.,Chen, Y.,Mi, YQ.,...&Guo, ZY.(2019).Synthesis of urea-functionalized chitosan derivatives for potential antifungal and antioxidant applications.CARBOHYDRATE POLYMERS,215,108-118. [14] Chen, Y.,Mi, YQ.,Sun, XQ.,Zhang, JJ.,Li, Q.,...&Guo, ZY.(2019).Novel Inulin Derivatives Modified with Schiff Bases: Synthesis, Characterization, and Antifungal Activity.POLYMERS,11(6),998. [15] Zhang, JJ,Tan, WQ,Wei, LJ,Dong, F,Li, Q,&Guo, ZY.(2019).Synthesis, Characterization, and Antioxidant Evaluation of Novel Pyridylurea-Functionalized Chitosan Derivatives.POLYMERS,11(6),951. [16] Wei, LJ,Mi, YQ,Zhang, JJ,Li, Q,Dong, F,&Guo, ZY.(2019).Evaluation of quaternary ammonium chitosan derivatives differing in the length of alkyl side-chain: Synthesis and antifungal activity.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,129,1127-1132. [17] Li, Q,Wei, LJ,Zhang, JJ,Gu, GD,&Guo, ZY.(2019).Significantly enhanced antioxidant activity of chitosan through chemical modification with coumarins.POLYMER CHEMISTRY,10(12),1480-1488. [18] Tan, WQ,Dong, F,Zhang, JJ,Zhao, X,Li, Q,&Guo, ZY.(2019).Physical and Antioxidant Properties of Edible Chitosan Ascorbate Films.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,67(9),2530-2539. [19] Wei, Lijie.,Li, Qing.,Chen, Yuan.,Zhang, Jingjing.,Mi, Yingqi.,...&Guo, Zhanyong.(2019).Enhanced antioxidant and antifungal activity of chitosan derivatives bearing 6-O-imidazole-based quaternary ammonium salts.CARBOHYDRATE POLYMERS,206,493-503. [20] Wei, LJ.,Tan, WQ.,Zhang, JJ.,Mi, YQ.,Dong, F.,...&Guo, ZY.(2019).Synthesis, Characterization, and Antifungal Activity of Schiff Bases of Inulin Bearing Pyridine ring.POLYMERS,11(2),371. [21] Zhang, Jingjing.,Tan, Wenqiang.,Mi, Yingqi.,Luan, Fang.,Wei, Lijie.,...&Guo, Zhanyong.(2019).Synthesis and Characterization of Inulin Derivatives Bearing Urea Groups with Promising Antifungal Activity.STARCH-STARKE,71(1-2),1800058-. [22] Chen, Yuan.,Mi, Yingqi.,Zhang, Jingjing.,Dong, Fang.,Li, Qing.,...&Guo, Zhanyong.(2018).Radical Scavenging Activities of Novel Cationic Inulin Derivatives.POLYMERS,10(12),1295. [23] Tan, Wenqiang,Zhang, Jingjing,Mi, Yingqi,Dong, Fang,Li, Qing,&Guo, Zhanyong.(2018).Synthesis, characterization, and evaluation of antifungal and antioxidant properties of cationic chitosan derivative via azide-alkyne click reaction.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,120(A),318-324. [24] Ma, Xuanxuan,Liu, Sujing,Liu, Ying,Li, Qing,Gu, Guodong,&Xia, Chuanhai.(2018).New insights into the effect of base on the dechlorination of DDT in isopropanol-water over Pd/C catalyst under mild conditions.CHEMICAL ENGINEERING JOURNAL,351,756-765. [25] Tan, Wenqiang,Zhang, Jingjing,Zhao, Xiang,Dong, Fang,Li, Qing,&Guo, Zhanyong.(2018).Synthesis and antioxidant action of chitosan derivatives with amino-containing groups via azide-alkyne click reaction and N-methylation.CARBOHYDRATE POLYMERS,199,583-592. [26] Luan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and Antifungal Activity of N-Quaternized and N-Diquaternized Chitin Derivatives.STARCH-STARKE,70(11-12),1800026. [27] Zhang, Jingjing.,Tan, Wenqiang.,Wang, Gang.,Yin, Xiuli.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, characterization, and the antioxidant activity of N,N,N-trimethyl chitosan salts.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,118(A),9-14. [28] Zhang, Jingjing,Luan, Fang,Li, Qing,Gu, Guodong,Dong, Fang,&Guo, Zhanyong.(2018).Synthesis of Novel Chitin Derivatives Bearing Amino Groups and Evaluation of Their Antifungal Activity.MARINE DRUGS,16(10),380. [29] Wei, Lijie.,Chen, Yuan.,Tan, Wenqiang.,Li, Qing.,Gu, Guodong.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and Antifungal Activity of Pyridine-Based Triple Quaternized Chitosan Derivatives.MOLECULES,23(10),2604-. [30] Mi, Yingqi.,Tan, Wenqiang.,Zhang, Jingjing.,Wei, Lijie.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and Antifungal Property of Hydroxypropyltrimethyl Ammonium Chitosan Halogenated Acetates.MARINE DRUGS,16(9),315. [31] Chen, Yuan,Tan, Wenqiang,Li, Qing,Dong, Fang,Gu, Guodong,&Guo, Zhanyong.(2018).Synthesis of inulin derivatives with quaternary phosphonium salts and their antifungal activity.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,113,1273-1278. [32] Li, Qing,Feng, Yan,Gu, Guodong,&Guo, Zhanyong.(2018).Synthesis of Novel Amino Lactose and Evaluation of Its Antioxidant Property.STARCH-STARKE,70(5-6),1700293. [33] Zhang, Jingjing.,Tan, Wenqiang.,Luan, Fang.,Yin, Xiuli.,Dong, Fang.,...&Guo, Zhanyong.(2018).Synthesis of Quaternary Ammonium Salts of Chitosan Bearing Halogenated Acetate for Antifungal and Antibacterial Activities.POLYMERS,10(5),530. [34] Wei, Lijie.,Zhang, Jingjing.,Luan, Fang.,Tan, Wenqiang.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, Characterization, and the Antifungal Property of Aminoethyl Chitosan Quaternary Ammonium Salts.STARCH-STARKE,70(5-6),1700266. [35] Luan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Mi, Yingqi.,Dong, Fang.,...&Guo, Zhanyong.(2018).Antioxidant Activity and Antifungal Activity of Chitosan Derivatives with Propane Sulfonate Groups.POLYMERS,10(4),395. [36] Li, Qing,Sun, Xueqi,Gu, Guodong,&Guo, Zhanyong.(2018).Novel Water Soluble Chitosan Derivatives with 1,2,3-Triazolium and Their Free Radical-Scavenging Activity.MARINE DRUGS,16(4),UNSP 107. [37] Zhang, Jingjing.,Tan, Wenqiang.,Zhang, Zhenpeng.,Song, Yinping.,Li, Qing.,...&Guo, Zhanyong.(2018).Synthesis, characterization, and the antifungal activity of chitosan derivatives containing urea groups.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,109,1061-1067. [38] Luan, Fang.,Wei, Lijie.,Zhang, Jingjing.,Tan, Wenqiang.,Chen, Yuan.,...&Guo, Zhanyong.(2018).Preparation and Characterization of Quaternized Chitosan Derivatives and Assessment of Their Antioxidant Activity.MOLECULES,23(3),516. [39] Luan, Fang.,Li, Qing.,Tan, Wenqiang.,Wei, Lijie.,Zhang, Jingjing.,...&Guo, Zhanyong.(2018).The evaluation of antioxidant and antifungal properties of 6-amino-6-deoxychitosan in vitro.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,107,595-603. [40] Tan, WQ.,Li, Q.,Zhou, TT.,Chen, QH.,Wang, G.,...&Guo, ZY.(2017).Synthesis and antioxidant ability of 6,6 '-diamino-6,6 '-dideoxytrehalose.BIOORGANIC CHEMISTRY,74,66-71. [41] Wei, Lijie.,Li, Qing.,Tan, Wenqiang.,Dong, Fang.,Luan, Fang.,...&zhanyongguo@hotmail.com.(2017).Synthesis, Characterization, and the Antioxidant Activity of Double Quaternized Chitosan Derivatives.MOLECULES,22(3),501. [42] Li, Qing,Qiu, Lishushi,Tan, Wenqiang,Gu, Guodong,Guo, Zhanyong,&Guo, Zhanyong.(2017).Novel 1,2,3-triazolium-functionalized inulin derivatives: synthesis, free radical-scavenging activity, and antifungal activity.RSC ADVANCES,7(67),42225-42232. [43] Li, Qing,Zhang, Caili,Tan, Wenqiang,Gu, Guodong,Guo, Zhanyong,&Guo, ZY .(2017).Novel Amino-Pyridine Functionalized Chitosan Quaternary Ammonium Derivatives: Design, Synthesis, and Antioxidant Activity.MOLECULES,22(1),156. [44] 李琬聪,李青,董方,等. 菊糖分子量的高效凝胶过滤色谱检测方法及其在贮藏过程中的变化研究[J]. 中国科学:生命科学,2016,46(9):1107-1112. [45] Guo, Zhanyong.,Li, Qing.,Wang, Gang.,Dong, Fang.,Zhou, Haoyuan.,...&Guo, ZY .(2014).Synthesis, characterization, and antifungal activity of novel inulin derivatives with chlorinated benzene.CARBOHYDRATE POLYMERS,99,469-473. [46] Li, Qing,Ren, Jianming,Dong, Fang,Feng, Yan,Gu, Guodong,&Guo, Zhanyong.(2013).Synthesis and antifungal activity of thiadiazole-functionalized chitosan derivatives.CARBOHYDRATE RESEARCH,373,103-107. [47] Li, Jiuyan,Duan, Yongheng,&Li, Qing.(2013).Novel thieno-[3,4-b]-pyrazine derivatives for non-doped red organic light-emitting diodes.DYES AND PIGMENTS,96(2),391-396. [48] Ren, Jianming,Li, Qing,Dong, Fang,Feng, Yan,&Guo, Zhanyong.(2013).Phenolic antioxidants-functionalized quaternized chitosan: Synthesis and antioxidant properties.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,53,77-81. [49] Liu, Di,Li, Qing,&Wang, Renjie.(2013).Synthesis and Electroluminescence of Thieno-[3,4-b]pyrazine-cored Molecule with Fluorinated Shell.AUSTRALIAN JOURNAL OF CHEMISTRY,66(5),594-599. [50] Li Qing,Li Jiuyan,Duan Yongheng,Gao Zhanxian,&Liu Di.(2011).Synthesis and Characterization of New Thienopyrazine-cored Dendrimer for Non-Doped Organic Red Light-Emitting Diodes.CHINESE JOURNAL OF CHEMISTRY,29(12),2655-2658.

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