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招生专业 083001-环境科学 0703Z1-化学生物学 招生方向 环境科学 分析化学 金属蛋白 教育背景 1995-09--2000-07 中国科学院生态环境研究中心 博士学位 工作简历 2013-12~现在, 中国科学院生态环境研究中心, 研究员 2001-01~2013-12,中国科学院生态环境研究中心, 副研究员 1995-09~2000-07,中国科学院生态环境研究中心, 博士学位 1995-08~2000-12,中国科学院生态环境研究中心, 助理研究员 1990-07~1995-07,中国科学院生态环境研究中心, 研究实习员 教授课程 环境化学实验 环境分子毒理学 奖励信息 (1) 食品中热点污染物监测控制标准与配套检验方法, 特等奖, 其他, 2014 专利成果 ( 1 ) 一种合成烷基汞的方法及其装置, 2010, 第 4 作者, 专利号: ZL 200710303716.9 ( 2 ) 一种用于分离和检测有机汞化合物含量的方法, 2011, 第 4 作者, 专利号: ZL 200710177665.X ( 3 ) 一种用于分离和检测纳米银的方法, 2014, 第 4 作者, 专利号: 201410238254.7 ( 4 ) 雾化室、采用其的进样系统和ICP-MS, 2018, 第 4 作者, 专利号: 201610227306.X ( 5 ) 用于蛋白分离的新型水平柱状凝胶电泳装置, 2016, 第 1 作者, 专利号: 201611101473.6 ( 6 ) 用于蛋白分离的水平柱状凝胶电泳槽, 2016, 第 1 作者, 专利号: 201611101526.4 ( 7 ) 用于蛋白分离的新型柱状凝胶管, 2016, 第 1 作者, 专利号: 201611101759.4 ( 8 ) 用于蛋白分离的新型柱状凝胶洗脱装置, 2016, 第 1 作者, 专利号: 201611101565.4 ( 9 ) 基质辅助激光解吸-串联飞行时间质谱仪靶板, 2018, 第 5 作者, 专利号: 201710371403.0 ( 10 ) 铅结合蛋白基因、包含其的蛋白及其应用, 2018, 第 5 作者, 专利号: 201810445673.6 ( 11 ) 用于蛋白分离的洗脱装置及采用其的柱状凝胶电泳装置, 2019, 第 1 作者, 专利号: ZL 201611101565.4 ( 12 ) 用于蛋白分离的电泳槽及采用其的柱状凝胶电泳装置, 2019, 第 1 作者, 专利号: ZL 201611101526.4 发表著作 Analytical Techniques for Clinical Chemistry, Chapter 15, John Wiley & Sons, Inc., 2012-06, 第 1 作者 ( 2 ) 环境样品前处理技术(第二版),第12章, 化学工业出版社, 2016-01, 第 1 作者 ( 3 ) 金属组学,第四章, 科学出版社, 2016-05, 第 2 作者 科研项目 ( 1 ) 典型中药中汞、砷和硒的形态及其生物有效性研究, 主持, 国家级, 2011-01--2013-12 ( 2 ) 我国环境汞污染的来源、化学特征及转化机制研究—汞的光化学甲基化过程及机理 , 参与, 国家级, 2010-01--2013-12 ( 3 ) 二维色谱—质谱技术在金属化合物诱导蛋白表达差异研究中的应用, 主持, 国家级, 2013-01--2016-12 ( 4 ) 我国汞污染特征、环境过程及减排技术原理, 参与, 国家级, 2013-01--2017-12 ( 5 ) 柱状凝胶色谱与质谱联用技术研究及其在金属蛋白分析中的应用, 主持, 国家级, 2016-01--2019-12 ( 6 ) 汞的微生物甲基化分子机制研究, 主持, 国家级, 2018-01--2021-12

近期论文

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(1) Revisiting the forms of trace elements in biogeochemical cycling: Analytical needs and challenges, TRAC-Trends in Analytical Chemistry, 2020, 第 4 作者 (2) Determination and characterization of metal nanoparticles in clams and oysters, Ecotoxicology and Environmental Safety, 2020, 第 4 作者 (3) Environmetallomics: Systematically investigating metals in environmentally relevant media, TRAC-Trends in Analytical Chemistry, 2020, 第 3 作者 (4) A 3D-printed modularized purification system for rapid, high-throughput MALDI-MS analysis of small-volume biological samples, Chemical Communications, 2020, 第 3 作者 (5) Cadmium-binding proteins in human blood plasma, Ecotoxicology and Environmental Safety, 2020, 第 3 作者 (6) Monitoring AuNP Dynamics in the Blood of a Single Mouse Using Single Particle Inductively Coupled Plasma Mass Spectrometry with an Ultralow-Volume High-Efficiency Introduction System, Analytical Chemistry, 2020, 第 9 作者 (7) 3D打印便携式凝胶电泳装置用于蛋白质的快速检测, 色谱, 2020, 第 8 作者 (8) Speciation of organomercury compounds by capillary electrophoresis, Chinese Chemical Letters, 2019, 通讯作者 (9) A case report of conjoined twins in medaka fish, Mol Reprod Dev., 2019, 第 3 作者 (10) 3D printed gel electrophoresis device coupling with ICP-MS for online, Talanta, 2019, 第 2 作者 (11) Methylmercury exposure alters RNA splicing in human neuroblastoma Sk-N-SH cells: Implications from proteomic and post-transcriptional responses, Environmental Pollution, 2018, 第 2 作者 (12) Characterization of mercury-binding proteins in human neuroblastoma Sk-N-SH cells with immobilized metal affinity chromatography, Talanta, 2018, 通讯作者 (13) Organotin exposure stimulates steroidogenesis in H295R Cell via cAMP pathway, Ecotoxicology and Environmental Safety, 2018, 通讯作者 (14) Antibacterial mechanism of silver nanoparticles in Pseudomonas aeruginosa: proteomics approach, Metallomics, 2018, 通讯作者 (15) Insight into the endocrine disrupting effect and cell response to butyltin compounds in H295R cell: Evaluated with proteomics and bioinformatics analysis, Science of the Total Environment, 2018, 通讯作者 (16) Two-dimensional (weak anion exchange chromatography-gel electrophoresis) separations coupling to inductively coupled plasma mass spectrometry strategy for analysis of metalloproteins, Talanta, 2018, 通讯作者 (17) Characterization of mercury-binding proteins in rat blood plasma, Chemical Communications, 2018, 第 2 作者 (18) 3D printing of graphene-doped target for ‘‘matrix-free’’ laser desorption/ionization mass spectrometry, Chemical Communications, 2018, 第 4 作者 (19) Headspace Solid-Phase Microextraction Coupled to Miniaturized Microplasma Optical Emission Spectrometry for Detection of Mercury and Lead, Analytical Chemistry, 2018, 通讯作者 (20) Speciation and bioaccessibility of arsenic in traditional Chinese medicines and assessment of its potential health risk, Science of the Total Environment, 2018, 通讯作者 (21) Determination of tetrabromobisphenol-A/S and their main derivatives in water samples by high performance liquid chromatography coupled with inductively coupled plasma tandem mass spectrometry, J. Chromatogr A., 2017, 第 5 作者 (22) Determining the Cytotoxicity of Rare Earth Element Nanoparticles in Macrophages and the Involvement of Membrane Damage, Environ. Sci. Technol., 2017, 第 8 作者 (23) Biological and behavioral factors modify urinary arsenic metabolic profiles in a U.S. population, Environ. Health, 2016, 第 3 作者 (24) Estimation of bioaccessibility and potential human health risk of mercury in Chinese patent medicines, J. Environm. Sci., 2016, 通讯作者 (25) Biomagnification of mercury in mollusks from coastal areas of the Chinese Bohai Sea, RSC Advances, 2015, 第 6 作者 (26) Efficient interface for online coupling of capillary electrophoresis with inductively coupled plasma-mass spectrometry and its application in simultaneous speciation analysis of arsenic and selenium, Anal. Chem., 2014, 通讯作者 (27) Identification and accurate size characterization of nanoparticles in complex media, Angwe. Chem. Int. Ed., 2014, 第 2 作者 (28) Speciation analysis of arsenic compounds by capillary electrophoresis on-line coupled with inductively coupled plasma mass spectrometry using a novel interface, J. Chromatogr. A, 2013, 通讯作者 (29) A candidate reference material Mya arenaria for the monitoring of butyltin compounds in mollusks in the marine environment, Anal. Methods, 2013, 通讯作者 (30) Research progress of heavy metal pollution in China: Sources, analytical methods, status, and toxicity, Chinese Science Bulletin, 2013, 第 1 作者 (31) Evaluation of different extraction procedures for determination of organic Mercury species in petroleum by high performance liquid chromatography coupled with cold vapor atomic fluorescence spectrometry, Talanta, 2013, 通讯作者 (32) Characterization of mercury-containing protein in human plasma, Metallomics, 2013, 通讯作者 (33) Characterization of interactions between organotin compounds and human, Talanta, 2012, 通讯作者 (34) 高效液相色谱-电感耦合等离子体质谱研究Medaka体内水溶性汞结合蛋白, 分析化学, 2011, 第 2 作者 (35) 中药中汞的形态分析方法、生物有效性与毒性效应研究, 环境化学, 2011, 第 3 作者 (36) 云南阳宗海砷污染水平、变化趋势及风险评估, 中国科学:化学, 2011, 第 2 作者 (37) Speciation of organotin compounds in environmental samples with semipermanent coated capillaries by capillary electrophoresis coupled with inductively coupled plasma mass spectrometry, Anal. Meth., 2010, 第 2 作者 (38) The levels, trends and risk assessment of arsenic pollution in Yangzonghai Lake, Yunnan, Sci. China-Chem., 2010, 第 2 作者 (39) L-cysteine-induced degradation of organic mercury as a novel interface in the HPLC-CV-AFS hyphenated system for speciation of mercury, J. Anal. At. Spectrom., 2010, 第 3 作者 (40) 液相色谱-原子荧光联用同时测定砷、硒形态, 色谱, 2010, 第 2 作者

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