个人简介
1. Lu R, Dong Y, Li JD*. Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery. Nucleic Acids Res, 2020, doi: 10.1093/nar/gkaa601.
2. Men M, Wang X, Wu J, Zeng W, Jiang F, Zheng R*, Li JD*. Prevalence and associated phenotypes of DUSP6, IL17RD and SPRY4 variants in a large Chinese cohort with isolated hypogonadotropic hypogonadism. J Med Genet. 2020. doi: 10.1136/jmedgenet-2019-106786.
3. Li JD#, Wu J#, Zhao Y#, Wang X, Jiang F, Hou Q, Chen DN, Zheng R, Yu R, Zhou W, Men M*. Phenotypic spectrum of idiopathic hypogonadotropic hypogonadism patients with CHD7 variants from a large Chinese cohort. J Clin Endocrinol Metab. 2019. doi: 10.1210/clinem/dgz182.
4. Zhao Y#, Wu J#, Jia H, Wang X, Zheng R, Jiang F, Chen DN, Chen Z*, Li JD*. PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling. FASEB J. 2019; 33(3): 4538-4546. doi: 10.1096/fj.201801575R.
5. Li X, Shi L, Zhang K, Wei W, Liu Q, Mao F, Li J, Cai W, Chen H, Teng H*, Li J*, Sun Z*, CirGRDB: a database for the genome-wide deciphering circadian genes and regulators. Nucleic Acids Res. 2018; 46(D1): D64-D70. doi: 10.1093/nar/gkx944.
6. Chen DN, Ma YT, Liu H, Zhou QY, Li JD*. Functional Rescue of Kallmann Syndrome-associated Prokineticin Receptor 2 (PKR2) Mutants Deficient in Trafficking. J Biol Chem. 2014; 289(22): 15518-15526.
7. Peng Z, Tang Y, Luo H, Jiang F, Yang J, Sun L, Li JD*. Disease-causing Mutation in PKR2 Receptor Reveals a Critical Role of Positive Charges in the Second Intracellular Loop for G-protein Coupling and Receptor Trafficking. J Biol Chem. 2011; 286(19): 16615-22. doi: 10.1074/jbc.M111.223784.
8. Li JD, Hu WP, Zhou QY*. Disruption of the circadian output molecule prokineticin 2 results in anxiolytic and antidepressant-like effects in mice. Neuropsychopharmacology. 2009; 34(2): 367-73. doi: 10.1038/npp.2008.61.
9. Li JD, Hu WP, Boehmer L, Cheng MY, Lee AG, Jilek A, Siegel JM, Zhou QY*. Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene. J Neurosci. 2006, 26(45): 11615-23.
10. Ng KL, Li JD, Cheng MY, Leslie FM, Lee AG, Zhou QY*. Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling. Science, 2005, 308 (5730): 1923-7.
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1. Lu R, Dong Y, Li JD*. Necdin regulates BMAL1 stability and circadian clock through SGT1-HSP90 chaperone machinery. Nucleic Acids Res, 2020, doi: 10.1093/nar/gkaa601.
2. Men M, Wang X, Wu J, Zeng W, Jiang F, Zheng R*, Li JD*. Prevalence and associated phenotypes of DUSP6, IL17RD and SPRY4 variants in a large Chinese cohort with isolated hypogonadotropic hypogonadism. J Med Genet. 2020. doi: 10.1136/jmedgenet-2019-106786.
3. Li JD#, Wu J#, Zhao Y#, Wang X, Jiang F, Hou Q, Chen DN, Zheng R, Yu R, Zhou W, Men M*. Phenotypic spectrum of idiopathic hypogonadotropic hypogonadism patients with CHD7 variants from a large Chinese cohort. J Clin Endocrinol Metab. 2019. doi: 10.1210/clinem/dgz182.
4. Zhao Y#, Wu J#, Jia H, Wang X, Zheng R, Jiang F, Chen DN, Chen Z*, Li JD*. PROKR2 mutations in idiopathic hypogonadotropic hypogonadism: selective disruption of the binding to a Gα-protein leads to biased signaling. FASEB J. 2019; 33(3): 4538-4546. doi: 10.1096/fj.201801575R.
5. Li X, Shi L, Zhang K, Wei W, Liu Q, Mao F, Li J, Cai W, Chen H, Teng H*, Li J*, Sun Z*, CirGRDB: a database for the genome-wide deciphering circadian genes and regulators. Nucleic Acids Res. 2018; 46(D1): D64-D70. doi: 10.1093/nar/gkx944.
6. Chen DN, Ma YT, Liu H, Zhou QY, Li JD*. Functional Rescue of Kallmann Syndrome-associated Prokineticin Receptor 2 (PKR2) Mutants Deficient in Trafficking. J Biol Chem. 2014; 289(22): 15518-15526.
7. Peng Z, Tang Y, Luo H, Jiang F, Yang J, Sun L, Li JD*. Disease-causing Mutation in PKR2 Receptor Reveals a Critical Role of Positive Charges in the Second Intracellular Loop for G-protein Coupling and Receptor Trafficking. J Biol Chem. 2011; 286(19): 16615-22. doi: 10.1074/jbc.M111.223784.
8. Li JD, Hu WP, Zhou QY*. Disruption of the circadian output molecule prokineticin 2 results in anxiolytic and antidepressant-like effects in mice. Neuropsychopharmacology. 2009; 34(2): 367-73. doi: 10.1038/npp.2008.61.
9. Li JD, Hu WP, Boehmer L, Cheng MY, Lee AG, Jilek A, Siegel JM, Zhou QY*. Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene. J Neurosci. 2006, 26(45): 11615-23.
10. Ng KL, Li JD, Cheng MY, Leslie FM, Lee AG, Zhou QY*. Dependence of olfactory bulb neurogenesis on prokineticin 2 signaling. Science, 2005, 308 (5730): 1923-7.
学术兼职
中国细胞生物学会理事
湖南省遗传学会秘书长、副理事长
湖南省实验动物学会副理事长
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