个人简介
马健，男，医学博士，现任中南大学肿瘤研究所副所长、非可控性炎症与肿瘤湖南省重点实验室副主任、湖南省免疫学会副理事长。本科毕业于湖南医科大学，博士毕业于中南大学肿瘤研究所。入选“教育部新世纪优秀人才支持计划”，获得湖南省杰出青年基金资助。
先后主持了6项国家自然科学基金，并参加了数项国家自然科学基金重点项目、973项目和863项目。论文发表在Advanced Science、Oncogene、Journal of Virology、Journal of Biological Chemistry、Journal of Immunology、Journal of Cell Science、International Journal of Cancer、Cancer Letters等杂志。参编专（译）著5 部：《基于WWW的生物信息学应用指南》、《现代肿瘤学基础》、《病理生理学》、《癌症-基础卷》和《非编码RNA与肿瘤》。2019年获得湖南省自然科学奖二等奖。
研究生招生方向：100104病理学与病理生理学（01肿瘤发病机制）、071009细胞生物学、071007 遗传学（01肿瘤遗传学）。
教育经历
1990.9-1995.7
湖南医科大学 | 预防医学 | 学士学位 | 大学本科毕业
科研项目
S100A8诱导PD-L1表达参与肿瘤免疫逃逸的机制,在研,国家自然科学基金,马健
乳铁蛋白调控肿瘤微环境的机制研究,在研,国家自然科学基金,马健
1999.9-2004.6
中南大学 | 病理学与病理生理学 | 博士学位 | 博士研究生毕业
获奖信息
湖南省自然科学奖二等奖|2019,马健
近期论文
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Li Z,.Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape..[J].美国:Journal of Immunology,2020,204(9):2589-2599
Peng Q,.Phase separation of Epstein-Barr Virus EBNA2 and Its Coactivator EBNALP controls gene expression.[J]:Journal of Virology,2020,94(7):e01771-19
Ou C,Sun Z.Targeting YAP1/LINC00152/FSCN1 signaling axis prevents the progression of colorectal cancer.[J]:Advanced Science,2019,7(3):1901380
Wang J, Zheng X, Qin Z, …, Lu J*, Ma J*.Epstein-Barr virus miR-BART3-3p promotes tumorigenesis by regulating the senescence pathway in gastric cancer.[J].PMID: 30674552:Journal of Biological Chemistry,2019,294(13):4854-4866
Zheng X, Wang J, Wei L, …, Ma J*.Epstein-Barr Virus miR-BART5-3p inhibits p53 expression.[J].PMID: 30209170:Journal of Virology,2018,92(23):e01022-18
Wang S, Song R, Wang Z, Jing Z, Wang S, Ma J*.S100A8/A9 in Inflammation:Frontiers in Immunology,2018,9:1298
Peng Q, Chen L, Wu W, …, Huang J*, Ma J*.EPH receptor A2 governs a feedback loop that activates Wnt/β-catenin signaling in gastric cancer.[J]:Cell Death & Disease,2018,9(12):1146
Lu Y, Qin Z, Wang J, …, Yan Q*, Ma J*.Epstein-Barr Virus miR-BART6-3p Inhibits the RIG-I Pathway.[J]:Journal of Innate Immunity,2017,9(6):574-586
Huang J, He Y, Mcleod HL, …, Ma J*, Chen Z*.miR-302b inhibits tumorigenesis by targeting EphA2 via Wnt/ β-catenin/EMT signaling cascade in gastric cancer.[J]:BMC Cancer,2017,17(1):886
Ou C, Sun Z, Li X, …, Li G*, Ma J*.MiR-590-5p, a density-sensitive microRNA, inhibits tumorigenesis by targeting YAP1 in colorectal cancer:Cancer Letters,2017,399:53-63
Zhang X, Wei L, Wang J, …, Ma J*.Suppression colitis and colitis-associated colon cancer by anti-S100a9 antibody in mice:Frontiers in Immunology,2017,8:1774
Dang W, Qin Z, Fan S, …, Ma J*.miR-1207-5p suppresses lung cancer growth and metastasis by targeting CSF1:Oncotarget,2016,7(22):32421-32432
Ren W, Shen S, Sun Z, …, Li X*, Ma J*.Jak-STAT3 pathway triggers DICER1 for proteasomal degradation by ubiquitin ligase complex of CUL4ADCAF1 to promote colon cancer development.[J]:Cancer Letters,2016,375(2):209-220
Qin Z, He W, Tang J, …, Yan Q*, Ma J*.MicroRNAs provide feedback regulation of epithelial-mesenchymal transition induced by growth factors.[J]:Journal of Cellular Physiology,2016,231(1):120-129
Zhang X, Ai F, Li X, …, Shen S*, Ma J*.Inflammation-induced S100A8 activates Id3 and promotes colorectal tumorigenesis.[J]:International Journal of Cancer,2015,137(12):2803-14
Ai F, Zhang X, Li X, …, Ma J*, Shen S*.Up-regulation of matrix metalloproteinases in a mouse model of chemically induced colitis-associated cancer: the role of microRNAs.[J]:Oncotarget,2015,6(7):5412-25
Zheng Y, Qin Z, Ye Q, …, Ma J*, Li G*.Lactoferrin suppresses the Epstein-Barr virus-induced inflammatory response by interfering with pattern recognition of TLR2 and TLR9.[J]:Laboratory Investigation,2014,94(11):1188-1199
Ye Q, Zheng Y, Fan S, …, Ma J*, Li G*.Lactoferrin deficiency promotes colitis-associated colorectal dysplasia in mice.[J]:PLoS One,2014,9(7):e103298
Zheng Y, Zhang W,Ye Q, …, Ma J*, Li G*.Inhibition of Epstein-Barr virus infection by lactoferrin:Journal of Innate Immunity,2014,4(4):387-398
Tang A, Li N, Li X, …, Ma J*, Shen S*.Dynamic activation of the key pathways: linking colitis to colorectal cancer in a mouse model.[J]:Carcinogenesis,2012,33(7):1375-1383
Deng M, Tang H, Zhou Y, …, Ma J*, Li G*.MiR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma.[J]:Journal of Cell Science,2011,124(Pt 17):2997-3005
Zhang L, Deng T, Li X, …, Ma J*, …, Li G*.microRNA-141 is involved in a nasopharyngeal carcinoma related genes network.[J]:Carcinogenesis,2010,31(4):559-566
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