陈艳 - 浙江海洋大学 - 食品与医药学院

个人简介

陈艳，女，博士研究生，2017年毕业于天津大学，在国内先进的合成生物学研究中心从事重要天然产物的生物制造。同年任教于浙江海洋大学。科研项目： 1、国家自然科学基金青年基金项目，21808208，酿酒酵母细胞工厂半乳糖调控的重构优化研究，2019.1-2021.12，项目主持人。 2、浙江省自然科学基金青年基金项目，LQ18B060004，虾青素生物合成过程中关键酶的定向改造和适配性研究，2018.01-2020.12，项目主持人。

研究领域

[1] 海洋药物的开发利用 [2] 天然产物的生物合成

近期论文

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(1) Yan Chen, Ying Wang, Ming Liu, Junze Qu, Mingdong Yao, Bo Li, Mingzhu Ding, Hong Liu, Wenhai Xiao(*), Yingjin Yuan. Primary and secondary metabolic effects of a key gene deletion (ΔYPL062W) on metabolically-engineered terpenoid-producing yeast. Applied and Environmental Microbiology, 2019. (2) Yan Chen, Ying Wang, Tian-Hua Chen, Ming-Dong Yao, Wen-Hai Xiao, Bing-Zhi Li, Ying-Jin Yuan(*). Identification and manipulation of a novel locus to improve cell tolerance to short-chain alcohols in Escherichia coli. Journal of Industrial Microbiology & Biotechnology, 2018, 45(7): 589-598. (3) Yan Chen, Wen-Hai Xiao(*), Ying Wang, Hong Liu, Xia Li, Ying-Jin Yuan, Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering, Microbial Cell Factories, 2016, 15(1): 113. (4) Chiara Martino, Louise Horsfall, Yan Chen, Mayuree Chanasakuli- yom, David Paterson, Adrien Brunet, Susan Rosser, Ying-Jin Yuan, Jonathan M. Cooper (*), Cytoskeletal Protein Expression and its Association within the Hydrophobic Membrane of Artificial Cell Models, ChemBioChem, 2012, 13(6):792-795. (5) Feng-Hua Chai(#), Ying Wang(#), Xue-Ang Mei(#), Ming-dong Yao, Yan Chen, Hong Liu, Wen-Hai Xiao(*), Ying-Jin Yuan, Heterologous biosynthesis and manipulation of crocetin in Saccharomyces cerevisiae, Microbial Cell Factories, 2017, 16(1): 54. (6) Yunzi Luo(#), Bing-Zhi Li(#), Duo Liu(#), Lu Zhang, Yan Chen, Bin Jia, Bo-Xuan Zeng, Huimin Zhao, Ying-Jin Yuan(*). Engineered Biosynthesis of Natural Products in Heterologous Hosts. Chemical Society Reviews, 2015, 44(15): 5265-5290. (7) Yi Wu(#), Bing-Zhi Li(#), Meng Zhao, Leslie A. Mitchell, Ze-Xiong Xie, Qiu-Hui Lin, Xia Wang, Wen-Hai Xiao, Ying Wang, Xiao Zhou, Hong Liu, Xia Li, Ming-Zhu Ding, Duo Liu, Lu Zhang, Bao-Li Liu, Xiao-Le Wu, Fei-Fei Li, Xiu-Tao Dong, Bin Jia, Wen-Zheng Zhang, Guo-Zhen Jiang, Yue Liu, Xue Bai, Tian-Qing Song, Yan Chen, Si-Jie Zhou, Rui-Ying Zhu, Feng Gao, Zheng Kuang, Xuya Wang, Michael Shen, Kun Yang, Giovanni Stracquadanio, Sarah M. Richardson, Yicong Lin, Lihui Wang, Roy Walker, Yisha Luo, Ping-Sheng Ma, Huanming Yang, Yizhi Cai, Junbiao Dai, Joel S. Bader, Jef D. Boeke, Ying-Jin Yuan(*). Bug mapping and fitness testing of chemically synthesized chromosome X. Science, 2017, 355: 1048.