王清 - 中国科学院烟台海岸带研究所 -

个人简介

2010年毕业于中科院海洋研究所海洋生态学专业，获理学博士学位。2010年7月至今，在中国科学院烟台海岸带研究所工作，历任助理研究员、副研究员、研究员。主要从事海洋生态毒理学研究，关注典型污染物对海洋生物的毒性效应和致毒机制。近年来主要关注我国近海沉积物、水体及海洋生物体内微塑料的污染现状，探讨典型海域微塑料的污染过程及其生态风险。作为项目负责人主持国家重点研发计划课题，国家自然科学基金面上项目，中科院A类先导项目子课题、中科院仪器装备项目、中科院青促会人才项目、中科院STS项目课题等20余项。在国内外学术期刊发表SCI论文60余篇，其中第一作者和通讯作者SCI文章30篇，发表论文总引用次数1600余次。获授权发明专利2项。2016年入选中科院青年创新促进会，2016年获中科院沈阳分院“沈阳分院第五届优秀青年科技人才奖”，2017年度获得中科院科技促进发展奖（排名第3）。研究内容我国近海沉积物、水体及海洋生物体内微塑料的污染现状，探讨典型海域微塑料的污染过程及其生态风险。教育背景 2007-09_2010-07 中国科学院海洋研究所博士研究项目 2013-01-01_2015-12-31 国家自然科学基金青年科学基金项目：菲律宾蛤仔对无机砷的甲基化及其分子机制研究 2016-01-01_2019-12-31 国家自然科学基金面上项目：莱州湾塑料微粒（microplastics）的污染现状及其毒性效应研究专利 [1] 冯巍巍,张永春,王清,等. 一种低功耗水质生态模拟与控制系统. 2016-09-05. [2] 赵建民,吴惠丰,王清,等. 一种紫贻贝g型溶菌酶基因及其重组蛋白和应用. 2011-12-15. [3] 王清,吴惠丰,赵建民,等. 紫贻贝g型溶菌酶基因及其重组蛋白和应用. 2011-12-15. [4] 吴惠丰,张林宝,赵建民,等. 菲律宾蛤仔防御素defensin B基因及其重组蛋白和应用. 2011-10-14. [5] 吴惠丰,张林宝,赵建民,等. 菲律宾蛤仔防御素defensin A基因及其重组蛋白和应用. 2011-10-14.

研究领域

微塑料对海洋生物的毒性效应污染物对海洋生物的毒性效应海洋生物对环境变化的适应和进化机制

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1] 王清,朱效鹏,赵建民. 滩涂生态牧场构建与展望[J]. 科技促进发展,2020,16(02):219-224. [2] Mohsen, M,Zhang, LB,Sun, LN,Lin, CG,Wang, Q,&Yang, HS.(2020).Microplastic fibers transfer from the water to the internal fluid of the sea cucumber Apostichopus japonicus.ENVIRONMENTAL POLLUTION,257,113606. [3] Zhu, Xiaopeng.,Ran, Wen.,Teng, Jia.,Zhang, Chen.,Zhang, Wenjing.,...&Wang, Qing.(2020).Microplastic Pollution in Nearshore Sediment from the Bohai Sea Coastline.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY. [4] Zhao, Y,Liu, H,Wang, Q,Li, BJ,Zhang, HX,&Pi, YR.(2019).The effects of benzo[a]pyrene on the composition of gut microbiota and the gut health of the juvenile sea cucumber Apostichopus japonicus Selenka.FISH & SHELLFISH IMMUNOLOGY,93,369-379. [5] Yang, DL.,Han, YJ.,Chen, LZ.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: Investigation on the antibacterial activities and antibacterial action mode.FISH & SHELLFISH IMMUNOLOGY,93,841-850. [6] Zhao, Y,Wang, Q,Liu, H,Li, BJ,&Zhang, HX.(2019).High-throughput sequencing of 16S rRNA amplicons characterizes gut microbiota shift of juvenile sea cucumber Apostichopus japonicus feeding with three antibiotics.JOURNAL OF OCEANOLOGY AND LIMNOLOGY,37(5),1714-1725. [7] Yang, DL.,Han, YJ.,Chen, LZ.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode.FISH & SHELLFISH IMMUNOLOGY,92,897-904. [8] Zhang, HX.,Wang, Q.,Liu, SL.,Huo, D.,Zhao, JM.,...&Yang, HS.(2019).Genomic and Metagenomic Insights Into the Microbial Community in the Regenerating Intestine of the Sea Cucumber Apostichopus japonicus.FRONTIERS IN MICROBIOLOGY,10,1165. [9] Mohsen, M,Wang, Q,Zhang, LB,Sun, LN,Lin, CG,&Yang, HS.(2019).Heavy metals in sediment, microplastic and sea cucumber Apostichopus japonicus from farms in China.MARINE POLLUTION BULLETIN,143,42-49. [10] Yang, DL.,Han, YJ.,Liu, YL.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).A peptidoglycan recognition protein involved in immune recognition and immune defenses in Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,88,441-448. [11] Hu, GG.,Han, YJ.,Yang, DL.,Cao, RW.,Wang, Q.,...&Zhao, JM.(2019).Molecular cloning and characterization of FADD from the manila clam Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,88,556-566. [12] Yang, DL.,Han, YJ.,Chen, LZ.,Liu, YL.,Cao, RW.,...&Zhao, JM.(2019).Scavenger receptor class B type I (SR-BI) in Ruditapes philippinarum: A versatile receptor with multiple functions.FISH & SHELLFISH IMMUNOLOGY,88,328-334. [13] Cao, RW.,Zhang, TY.,Li, X.,Zhao, YT.,Wang, Q.,...&Zhao, JM.(2019).Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas.AQUATIC TOXICOLOGY,210,167-178. [14] Zhu, N.,Yang, YY.,Xu, H.,Wang, Q.,Wei, YY.,...&Fang, Y.(2019).Bioaccumulation of decabromodiphenyl ether affects the antioxidant system in the clam Mactra veneriformis.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,68,19-26. [15] Zhang, B.,Wu, D.,Yang, X.,Teng, J.,Liu, YL.,...&Wang, Q.(2019).Microplastic pollution in the surface sediments collected from Sishili Bay, North Yellow Sea, China.MARINE POLLUTION BULLETIN,141,9-15. [16] Teng, J.,Wang, Q.,Ran, W.,Wu, D.,Liu, YF.,...&Zhao, JM.(2019).Microplastic in cultured oysters from different coastal areas of China.SCIENCE OF THE TOTAL ENVIRONMENT,653,1282-1292. [17] Mohsen, Mohamed,Wang, Qing,Zhang, Libin,Sun, Lina,Lin, Chenggang,&Yang, Hongsheng.(2019).Microplastic ingestion by the farmed sea cucumber Apostichopus japonicus in China.ENVIRONMENTAL POLLUTION,245,1071-1078. [18] Zhao, Ye,Liu, Hui,Wang, Qing,&Li, Bingjun.(2019).The influence of three antibiotics on the growth, intestinal enzyme activities, and immune response of the juvenile sea cucumber Apostichopus japonicus selenka.FISH & SHELLFISH IMMUNOLOGY,84,434-440. [19] 张晨,王清,赵建民. 海洋微塑料输运的数值模拟研究进展[J]. 地球科学进展,2019,34(1):72-83. [20] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Dong, Zhijun.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses.SCIENCE OF THE TOTAL ENVIRONMENT,642,809-823. [21] Chen, Lizhu.,Wu, Huifeng.,Zhao, Jianmin.,Zhang, Wei.,Zhang, Li.,...&Wang, Qing.(2018).The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum.AQUATIC TOXICOLOGY,204,9-18. [22] Wang Q.(2018).Microplastic pollution in sediments from the Bohai Sea and the Yellow Sea, China.Science of the Total Environment,640(640-641),637-645. [23] 冉文,滕佳,刘永亮,等. 环渤海潮间带长牡蛎微塑料富集特征研究[J]. 海洋通报,2018,37(05):583-590. [24] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Zhang, Qianqian.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas.FISH & SHELLFISH IMMUNOLOGY,81,456-462. [25] Yang, Dinglong.,Zhang, Qianqian.,Wang, Qing.,Chen, Lizhu.,Liu, Yongliang.,...&Zhao, Jianmin.(2018).A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action.FISH & SHELLFISH IMMUNOLOGY,80,274-280. [26] Cao, Ruiwen.,Wang, Dan.,Wei, Qianyu.,Wang, Qing.,Yang, Dinglong.,...&Zhao, Jianmin.(2018).Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri.FRONTIERS IN PHYSIOLOGY,9,1173. [27] Cao, Ruiwen.,Liu, Yongliang.,Wang, Qing.,Yang, Dinglong.,Liu, Hui.,...&Zhao, Jianmin.(2018).Seawater Acidification Reduced the Resistance of Crassostrea gigas to Vibrio splendidus Challenge: An Energy Metabolism Perspective.FRONTIERS IN PHYSIOLOGY,9,880. [28] Wang, Dan.,Yang, Dinglong.,Wang, Qing.,Zhao, Ye.,Li, Chenghua.,...&Zhao, Jianmin.(2018).Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities.FISH & SHELLFISH IMMUNOLOGY,78,158-168. [29] Cao, Ruiwen.,Wang, Qing.,Yang, Dinglong.,Liu, Yongliang.,Ran, Wen.,...&Zhao, Jianmin.(2018).CO2-induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective.SCIENCE OF THE TOTAL ENVIRONMENT,625,1574-1583. [30] Cong, Ming.,Wu, Huifeng.,Cao, Tengfei.,Lv, Jiasen.,Wang, Qing.,...&Zhao, Jianmin.(2018).Digital gene expression analysis in the gills of Ruditapes philippinarum exposed to short- and long-term exposures of ammonia nitrogen.AQUATIC TOXICOLOGY,194,121-131. [31] Xie, Jia.,Yang, Dinglong.,Sun, Xiyan.,Cao, Ruiwen.,Chen, Lizhu.,...&Zhao, Jianmin.(2017).Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,99(5),582-588. [32] Yu, Qian.,Yang, Dinglong.,Wang, Qing.,Zhang, Yingying.,Cong, Ming.,...&Zhao, Jianmin.(2017).Molecular characterization, expression and functional analysis of two Kazal-type serine protease inhibitors from Venerupis philippinarum.FISH & SHELLFISH IMMUNOLOGY,70,156-163. [33] Xie, J.,Yang, DL.,Sun, XY.,Cao, RW.,Chen, LZ.,...&Zhao, JM.(2017).Individual and Combined Toxicities of Benzo[a]pyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas.BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY,99(5),582-588. [34] 刘佳琳,徐兰兰,路珍,等. 基于核磁共振的褐牙鲆幼鱼组织代谢组学分析[J]. 海洋通报,2017,36(5):538-546. [35] 刘甜雨,王清,陈慕雁. 热刺激对栉孔扇贝免疫功能和热休克蛋白表达的影响[J]. 中国海洋大学学报. 自然科学版,2017,47(8):31-43. [36] Yang, Dinglong.,Wang, Qing.,Cao, Ruiwen.,Chen, Lizhu.,Liu, Yongliang.,...&Zhao, Jianmin.(2017).Molecular characterization, expression and antimicrobial activities of two c-type lysozymes from manila clam Venerupis philippinarum.DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY,73,109-118. [37] 陈丽竹,王丹,曹瑞文,等. 菲律宾蛤仔对三价和五价无机砷的富集转化规律[J]. 海洋通报,2017,36(3):326-332. [38] Yang, Dinglong.,Wang, Qing.,Chen, Lizhu.,Liu, Yongliang.,Cao, Ruiwen.,...&Zhao, Jianmin.(2017).Molecular characterization and antibacterial activity of a phage-type lysozyme from the Manila clam, Ruditapes philippinarum.FISH & SHELLFISH IMMUNOLOGY,65,17-24. [39] Sun, Lina,Sun, Jingchun,Li, Xiaoni,Zhang, Libin,Yang, Hongsheng,&Wang, Qing.(2017).Understanding regulation of microRNAs on intestine regeneration in the sea cucumber Apostichopus japonicus using high-throughput sequencing.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS,22,1-9. [40] Wu, Huifeng.,Liu, Jialin.,Lu, Zhen.,Xu, Lanlan.,Ji, Chenglong.,...&Wu, HF .(2017).Metabolite and gene expression responses in juvenile flounder Paralichthys olivaceus exposed to reduced salinities.FISH & SHELLFISH IMMUNOLOGY,63,417-423. [41] Xie, J..,Yang, D..,Sun, X..,Cao, R..,Chen, L..,...&Zhao, J..(2017).Combined toxicity of cadmium and lead on early life stages of the Pacific oyster, Crassostrea gigas.ISJ-INVERTEBRATE SURVIVAL JOURNAL,14,210-220. [42] Xie, Jia.,Zhao, Yun.,Wang, Qing.,Wu, Huifeng.,Teng, Jia.,...&Zhao, JM .(2016).An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas (vol 112, pg 318, 2016).MARINE POLLUTION BULLETIN,113(1-2),600-600. [43] Ji, CL.,Yu, DL.,Wang, Q.,Li, F.,Zhao, JM.,...&Wu, HF .(2016).Impact of metal pollution on shrimp Crangon affinis by NMR-based metabolomics.MARINE POLLUTION BULLETIN,106(1-2),372-376. [44] Ji, CL.,Li, F.,Wang, Q.,Zhao, JM.,Sun, ZD.,...&Wu, HF .(2016).An integrated proteomic and metabolomic study on the gender-specific responses of mussels Mytilus galloprovincialis to tetrabromobisphenol A (TBBPA).CHEMOSPHERE,144,527-539. [45] Wang, Q.,Cao, RW.,Ning, XX.,You, LP.,Mu, CK.,...&Zhao, JM .(2016).Effects of ocean acidification on immune responses of the Pacific oyster Crassostrea gigas.FISH & SHELLFISH IMMUNOLOGY,49,24-33. [46] Ji, CL,Wang, Q,Wu, HF,Tan, QG,Wang, WX,&Wu, HF .(2016).A metabolomic study on the biological effects of metal pollutions in oysters Crassostrea sikamea.MARINE POLLUTION BULLETIN,102(1),216-222. [47] 于倩,王清,韩伟,等. 具槽帕拉藻代谢组提取方法的比较研究[J]. 海洋通报,2015,34(6):703-709. [48] 于倩,王清,袁泽轶,等. 不同形态磷源对具槽帕拉藻(Paralia sulcata)生长和磷酸酶活性的影响[J]. 海洋与湖沼,2015,46(5):1018-1023. [49] Li Fei,Wu Huifeng,Wang Qing,Li Xuehua,Zhao Jianmin,&Wu, HF .(2015).Glutathione S-transferase (GST) gene expression profiles in two marine bivalves exposed to BDE-47 and their potential molecular mechanisms.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,33(3),705-713. [50] Wei, Lei.,Wang, Qing.,Ning, Xuanxuan.,Mu, Changkao.,Wang, Chunlin.,...&jmzhao@yic.ac.cn.(2015).Combined metabolome and proteome analysis of the mantle tissue from Pacific oyster Crassostrea gigas exposed to elevated pCO(2).COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS,13,16-23. [51] Ji, Chenglong,Wang, Qing,Wu, Huifeng,Tan, Qiaoguo,Wang, Wen-Xiong,&Wu, HF .(2015).A metabolomic investigation of the effects of metal pollution in oysters Crassostrea hongkongensis.MARINE POLLUTION BULLETIN,90(1-2),317-322. [52] Wei, Lei.,Wang, Qing.,Wu, Huifeng.,Ji, Chenglong.,Zhao, Jianmin.,...&jmzhao@yic.ac.cn.(2015).Proteomic and metabolomic responses of Pacific oyster Crassostrea gigas to elevated pCO(2) exposure.JOURNAL OF PROTEOMICS,112,83-94. [53] Liu, Xiaoli.,Ji, Chenglong.,Zhao, Jianmin.,Wang, Qing.,Li, Fei.,...&Liu, XL .(2014).Metabolic profiling of the tissue-specific responses in mussel Mytilus galloprovincialis towards Vibrio harveyi challenge.FISH & SHELLFISH IMMUNOLOGY,39(2),372-377. [54] Zhang, Yingying.,Wang, Qing.,Ji, Yinglu.,Zhang, Qian.,Wu, Huifeng.,...&jmzhao@yic.ac.cn.(2014).Identification and mRNA expression of two 17 beta-hydroxysteroid dehydrogenase genes in the marine mussel Mytilus galloprovincialis following exposure to endocrine disrupting chemicals.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,37(3),1243-1255. [55] Wang, Q..,Ning, X..,Zhang, Q..,Liu, F..,Wu, H..,...&jmzhao@yic.ac.cn.(2014).Molecular characterization of two glutathione peroxidase genes in Mytilus galloprovincialis and their transcriptional responses to sub-chronic arsenate and cadmium exposure.ISJ-INVERTEBRATE SURVIVAL JOURNAL,11,149-162. [56] 林晓玲,王清,袁泽轶,等. 菲律宾蛤仔(Ruditapes philippinarum)金属硫蛋白基因克隆及Cd~(2+)胁迫下的表达分析[J]. 海洋与湖沼,2014,45(5):1006-1012. [57] 章盈盈,袁泽轶,王清,等. 菲律宾蛤仔(Venerupis philippinarum)Rho 型GST和微粒体型GST 的序列分析及表达特征研究[J]. 海洋与湖沼,2014,45(4):798-805. [58] Liu, Xiaoli,Zhao, Jianmin,Wu, Huifeng,&Wang, Qing.(2013).Metabolomic analysis revealed the differential responses in two pedigrees of clam Ruditapes philippinarum towards Vibrio harveyi challenge.FISH & SHELLFISH IMMUNOLOGY,35(6),1969-1975. [59] Ji, Chenglong,Wu, Huifeng,Wei, Lei,Zhao, Jianmin,Wang, Qing,&Lu, Hongjian.(2013).Responses of Mytilus galloprovincialis to bacterial challenges by metabolomics and proteomics.FISH & SHELLFISH IMMUNOLOGY,35(2),489-498. [60] You, Liping,Ning, Xuanxuan,Liu, Feng,Zhao, Jianmin,Wang, Qing,&Wu, Huifeng.(2013).The response profiles of HSPA12A and TCTP from Mytilus galloprovincialis to pathogen and cadmium challenge.FISH & SHELLFISH IMMUNOLOGY,35(2),343-350. [61] Wang, Qing.,Wang, Chunyan.,Mu, Changkao.,Wu, Huifeng.,Zhang, Linbao.,...&jmzhao@yic.ac.cn.(2013).A Novel C-Type Lysozyme from Mytilus galloprovincialis: Insight into Innate Immunity and Molecular Evolution of Invertebrate C-Type Lysozymes.PLOS ONE,8(6),e67469. [62] Wang, Qing,Yuan, Zeyi,Wu, Huifeng,Liu, Feng,&Zhao, Jianmin.(2013).Molecular characterization of a manganese superoxide dismutase and copper/zinc superoxide dismutase from the mussel Mytilus galloprovincialis.FISH & SHELLFISH IMMUNOLOGY,34(5),1345-1351. [63] Wang Qing.,Ning Xuanxuan.,Pei Dong.,Zhao Jianmin.,You Liping.,...&Wu Huifeng.(2013).Molecular cloning, characterization and expression profiles of thioredoxin 1 and thioredoxin 2 genes in Mytilus galloprovincialis.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(3),493-503. [64] Wu, Huifeng.,Zhang, Xingyan.,Wang, Qing.,Li, Lianzhen.,Ji, Chenglong.,...&Yin, Xiuli.(2013).A metabolomic investigation on arsenic-induced toxicological effects in the clam Ruditapes philippinarum under different salinities.ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,90,1-6. [65] Wang, Chunyan,Zhao, Jianmin,Mu, Changkao,Wang, Qing,Wu, Huifeng,&Wang, Chunlin.(2013).cDNA cloning and mRNA expression of four glutathione S-transferase (GST) genes from Mytilus galloprovincialis.FISH & SHELLFISH IMMUNOLOGY,34(2),697-703. [66] Wu Huifeng,Ji Chenglong,Wang Qing,Liu Xiaoli,Zhao Jianmin,&Feng Jianghua.(2013).Manila clam Venerupis philippinarum as a biomonitor to metal pollution.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,31(1),65-74. [67] Wang, Qing,Zhang, Linbao,Zhao, Jianmin,You, Liping,&Wu, Huifeng.(2012).Two Goose-Type Lysozymes in Mytilus galloprovincialis: Possible Function Diversification and Adaptive Evolution.PLOS ONE,7(9),e45148. [68] Wang, Qing,Yang, Hongsheng,Liu, Baozhong,&Wang, Xiaoyu.(2012).Toxic effects of benzo[a]pyrene (Bap) and Aroclor1254 on embryogenesis, larval growth, survival and metamorphosis of the bivalve Meretrix meretrix.ECOTOXICOLOGY,21(6),1617-1624. [69] Zhang, Lei.,Ning, Xuanxuan.,Chen, Leilei.,Li, Chenghua.,Liu, Feng.,...&Zhao, Jianmin.(2012).Molecular cloning and expression analysis of a selenium-independent glutathione peroxidase identified from Manila clam Venerupis philippinarum.AQUACULTURE RESEARCH,43(8),1176-1183. [70] Zhang Linbao.,Wu Huifeng.,Liu Xiaoli.,Chen Leilei.,Wang Qing.,...&You Liping.(2012).Molecular cloning and differential expression patterns of sigma and omega glutathione S-transferases from Venerupis philippinarum to heavy metals and benzo[a]pyrene exposure.CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY,30(3),413-423. [71] Zhang, Linbao.,Qiu, Lihua.,Wu, Huifeng.,Liu, Xiaoli.,You, Liping.,...&Zhao, Jianmin.(2012).Expression profiles of seven glutathione S-transferase (GST) genes from Venerupis philippinarum exposed to heavy metals and benzo[a]pyrene.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,155(3),517-527. [72] Mu, Changkao,Wang, Qing,Yuan, Zeyi,Zhang, Zhendong,&Wang, Chunlin.(2012).Identification of glutaredoxin 1 and glutaredoxin 2 genes from Venerupis philippinarum and their responses to benzo[a]pyrene and bacterial challenge.FISH & SHELLFISH IMMUNOLOGY,32(3),482-488. [73] Wang, Qing.,Ning, Xuanxuan.,Chen, Leilei.,Pei, Dong.,Zhao, Jianmin.,...&Wu, Huifeng.(2011).Responses of thioredoxin 1 and thioredoxin-related protein 14 mRNAs to cadmium and copper stresses in Venerupis philippinarum.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,154(3),154-160. [74] Zhang, Linbao.,Liu, Xiaoli.,You, Liping.,Zhou, Di.,Wang, Qing.,...&Wu, Huifeng.(2011).Benzo(a)pyrene-induced metabolic responses in Manila clam Ruditapes philippinarum by proton nuclear magnetic resonance (H-1 NMR) based metabolomics.ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY,32(2),218-225. [75] Liu, Xiaoli.,Zhang, Linbao.,You, Liping.,Wu, Huifeng.,Zhao, Jianmin.,...&Yu, Junbao.(2011).Metabolomic Study on the Halophyte Suaeda salsa in the Yellow River Delta.CLEAN-SOIL AIR WATER,39(8),720-727. [76] Liu, Xiaoli.,Zhang, Linbao.,You, Liping.,Yu, Junbao.,Cong, Ming.,...&Wu, Huifeng.(2011).Assessment of Clam Ruditapes philippinarum as Heavy Metal Bioindicators Using NMR-Based Metabolomics.CLEAN-SOIL AIR WATER,39(8),759-766. [77] Liu, Xiaoli.,Zhang, Linbao.,You, Liping.,Yu, Junbao.,Zhao, Jianmin.,...&Wu, Huifeng.(2011).Differential toxicological effects induced by mercury in gills from three pedigrees of Manila clam Ruditapes philippinarum by NMR-based metabolomics.ECOTOXICOLOGY,20(1),177-186.