李宝强 - 中国科学院大学

个人简介

招生专业 083100-生物医学工程招生方向生物医学光子学，神经光学，脑与视网膜成像教育背景 2009-01--2014-08 蒙特利尔大学工学院博士 2006-09--2008-08 天津大学硕士 2002-09--2006-06 聊城大学学士工作简历 2020-01~现在, 中国科学院深圳先进技术研究院, 副研究员 2015-06~2019-12,哈佛医学院/麻省总医院, 博士后 2014-09~2015-05,蒙特利尔大学工学院, 博士后 2009-01~2014-08,蒙特利尔大学工学院, 博士 2006-09~2008-08,天津大学, 硕士 2002-09~2006-06,聊城大学, 学士奖励信息（1） Awarded student travel stipend to attend World Molecular Imaging Congress, 其他, 2011 （2） Winning Award, Future Innovators University Design Competition, 其他, 2007 （3）校级优秀毕业生, 研究所（学校）, 2006 专利成果（ 1 ）一种线状激光窄带滤光PSD热辐射板厚测量方法, 2010, 第 4 作者, 专利号: CN200810152457.9 科研项目（ 1 ）项目名称：脑功能环路研究的新技术方法和工具的研发与转化；说明：本人承担部分科研任务，“参与”角色还未加入课题，以下科研经费为本人承担的部分。, 参与, 省级, 2019-01--2021-12 参与会议（1）Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion 2019-04-11 （2）Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion 2019-02-02 （3）Two-photon microscopy imaging of capillary red blood cell flux in mouse brain reveals vulnerability of white matter to hypoperfusion 2018-10-03 （4）Cortical depth specific capillary blood flow homogenization facilitates resting state brain oxygen delivery 2018-07-08 （5）Cerebral oxygenation and blood flow distributions along the capillary path in awake mice 2018-01-27 （6）Cerebral oxygenation and blood flow distributions along the capillary path in awake mice 2017-11-11 （7）Investigation of the red blood cells flux change during hypercapnia in the rat brain with optical coherence tomography 2015-02-07 （8）MRI-guided fiber-based fluorescence molecular tomography for preclinical atherosclerosis imaging 2014-05-28 （9）Ultrasound guided fluorescence tomography 2012-06-06 （10）A Low Cost Fluorescence/Ultrasound Multimodal imaging System 2011-09-07

近期论文

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（1） Label-free assessment of hemodynamics in individual cortical brain vessels using third harmonic generation microscopy, Biomed. Opt. Express, 2020, 第 3 作者（2） A Pilot Study Investigating Changes in Capillary Hemodynamics and Its Modulation by Exercise in the APP-PS1 Alzheimer Mouse Model, Front. Neurosci., 2019, 第 3 作者（3） Voluntary exercise increases brain tissue oxygenation and spatially homogenizes oxygen delivery in a mouse model of Alzheimer's Disease, Neurobiol. Aging, 2019, 第 3 作者（4） Hypertension accelerates cerebral tissue PO2 disruption in Alzheimer’s disease, Neurosci. Lett., 2019, 第 3 作者（5） Atherosclerosis is associated with a decrease in cerebral microvascular blood flow and tissue oxygenation, PLoS One, 2019, 第 1 作者（6） More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction, eLife, 2019, 第 1 作者（7） Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion, J. Cereb. Blood Flow Metab., 2019, 第 1 作者（8） Awake mouse imaging: from 2-photon microscopy to BOLD fMRI, Biol. Psychiatry Cogn. Neurosci. Neuroimaging, 2018, 第 8 作者（9） Shear-Induced Diffusion of Red Blood Cells Measured with Dynamic Light Scattering-Optical Coherence Tomography, J. Biophotonics, 2017, 第 3 作者（10） Development of a new bioactivatable fluorescent probe for quantification of apolipoprotein A-I proteolytic degradation in vitro and in vivo, Atherosclerosis, 2017, 第 2 作者（11） Impact of temporal resolution on estimating capillary RBC-flux with optical coherence tomography, J. Biomed. Opt., 2017, 第 1 作者（12） Contribution of low- and high-flux capillaries to slow hemodynamic fluctuations in the cerebral cortex of mice, J. Cereb. Blood Flow Metab., 2016, 第 1 作者（13） Ultrasound guided fluorescence molecular tomography with improved quantification by an attenuation compensated born-normalization and in vivo preclinical study of cancer, Rev. Sci. Instrum., 2014, 第 1 作者（14） Hybrid FMT-MRI applied to in vivo atherosclerosis imaging, Biomed. Opt. Express, 2014, 第 1 作者（15） Low-cost three-dimensional imaging system combining fluorescence and ultrasound, J. Biomed. Opt., 2011, 第 1 作者