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1.Lyu H, Wang H, Li L, Zhu J, Chen F, Chen Y, Liu C1, Fu J, Yang B, Zhang Q, Xu Y*, Pi J* Hepatocyte-specific deficiency of Nrf2 exacerbates carbon tetrachloride-induced liver fibrosis via aggravated hepatocyte injury and subsequent inflammatory and fibrogenic responses. Free Radic Biol Med. 2020; 150:136-147. IF=5.657
2.Li L, Fu J, Liu D, Sun J, Hou Y, Chen C, Shao J, Wang L, Wang X, Zhao R, Wang H, Andersen ME, Zhang Q, Xu Y, Pi J* Hepatocyte-specific Nrf2 Deficiency Mitigates High-Fat Diet-Induced Hepatic Steatosis: Involvement of Reduced PPARγ Expression. Redox Biol.2020; 30:101412. IF=7.793
3.Xue P, Hou Y, Zuo Z, Wang Z, Ren S, Dong J, Fu J, Wang H, Andersen ME, Zhang Q, Xu Y∗, Pi J∗ Long Isoforms of NRF1 Negatively Regulate Adipogenesis via Suppression of PPARγ Expression. Redox Biol. 2020; 30:1014 IF=7.793
4.Luan J, Fu J, Chen C, Jiao C, Kong W, Zhang Y, Chang Q, Wang Y, Li D, Illei GG, Kopp JB, Pi J*, Zhou H*, LNA-anti-miR-150 ameliorated kidney injury of lupus nephritis by inhibiting renal fibrosis and macrophage infiltration. Arthritis Res Ther. 2019; 2019; 21:276. IF=4.148
5.Qi H, Fu J, Luan J, Jiao C, Cui X, Cao X, Zhang Y, Wang Y, Kopp JB, Pi J*, Zhou H*. miR-150 inhibitor ameliorates adriamycin-induced focal segmental glomerulosclerosis. Biochem Biophys Res Commun. 2020; 522:618-625. IF=2.705
6.Zuo Z, Liu Z, Gao T, Yin Y, Wang Z, Hou Y*, Fu J, Liu S, Wang H, Xu Y, Pi J*. Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice. Sci Total Environ. 2019; 668:310-317. IF =5.589
7.Liu Z, Hou Y, Li L, Yang Y, Jia J, Hong Z, Li T, Xu Y, Fu J, Sun Y, Yamamoto M, Wang H*, Pi J*. Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic. Toxicol Appl Pharmacol. 2019; 367:62-70. IF=3.616
8.Li L, Fu J*, Sun J, Liu D, Chen C, Wang H, Hou Y, Xu Y, Pi J*. Is Nrf2-ARE a potential target in mitigation of non-alcoholic fatty liver disease? Current Opinion in Toxicology. 2019; 13:35–44.
9.Pi J, Hayes JD, Yamamoto M. New Insights into Nuclear factor erythroid 2-related factors in Toxicology and Pharmacology. (Editorial) Toxicol Appl Pharmacol. 2019; 367:33-35 IF= 3.616
10.Zhu J, Wang H*, Chen F, Lv H, Xu Z, Fu J, Hou Y, Xu Y, Pi J*. Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity. Toxicol Appl Pharmacol. 2018; 58:1-9. IF= 3.616
11.Xu Y., Fu J., Wang H., Hou Y., Pi J. (2019) Arsenic Exposure and Lifestyle-Related Diseases. In: Yamauchi H., Sun G. (eds) Arsenic Contamination in Asia. Current Topics in Environmental Health and Preventive Medicine. Springer, Singapore. https://doi.org/10.1007/978-981-13-2565-6_6
12.Sun J, Fu J*, Li L, Chen C, Wang H, Hou Y, Xu Y, Pi J*. Nrf2 in alcoholic liver disease. Toxicol Appl Pharmacol. 2018; 57:62-69. IF= 3.616
13.Sun J, Fu J*, Zhong Y, Li L, Chen C, Wang X, Wang L, Hou Y, Wang H, Zhao R, Zhang X, Yamamoto M, Xu Y, Pi J*. NRF2 mitigates acute alcohol-induced hepatic and pancreatic injury in mice. Food Chem Toxicol. 2018; 21:495-503. IF= 3.977
14.Hou Y, Liu Z, Zuo Z, Gao T, Fu J, Wang H, Xu Y, Liu D, Yamamoto M, Zhu B, Zhang Y, Andersen ME, Zhang Q, Pi J*. Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice. Biochem Biophys Res Commun. 2018; 3:264-270. IF= 2.559
15.Wang H, Zhu J, Liu Z, Lv H, Lv P, Chen F, Fu J, Hou Y, Zhao R, Xu Y, Zhang Q, Pi J*. Silencing of long isoforms of Nuclear factor erythroid 2-related factor 1 primes macrophages towards M1 polarization. Free Radic Biol Med. 2018；117:37-44. IF=5.606.
16.Fu J, Zheng H, Cui Q, Chen C, Bao S, Sun J, Li L, Yang B, Wang H, Hou Y, Xu Y, Xu Y, Zhang Q, Pi J*. Nfe2l1 silenced insulinoma cells acquire aggressiveness and chemo-resistance. Endocr Relat Cancer. 2017；pii: ERC-17-0458. doi: 10.1530/ERC-17-0458. IF=5.267.
17.Wang H, Zhu J, Li L, Li Y, Lv H, Xu Y, Sun G, Pi J*. Effects of Nrf2 deficiency on arsenic metabolism in mice. Toxicol Appl Pharmacol. 2017; 37:111-119. IF=3.791
18.Kong W, Fu J, Liu N, Jiao C, Guo G, Luan J, Wang H, Yao Y, Wang L, Yamamoto M, Pi J*, Zhou H*. Nrf2 deficiency promotes the progression from acute tubular damage to chronic renal fibrosis following unilateral ureteral obstruction. Nephrol Dial Transpl.2018; 33:771-783. IF=4.47
19.Chen F, Wang H, Zhu J, Zhao R, Xue P, Zhang Q, Nelson MB, Qu W, Feng B*, Pi J*. Camptothecin suppresses NRF2-ARE activity and sensitizes hepatocellular carcinoma cells to anticancer drugs. Br J Cancer. 2017; 117:1495-1506. IF=6.176
20.Cui Q, Fu J*, Hu Y, Li Y, Yang B, Li L, Sun J, Chen C, Sun G, Xu Y, Zhang Q, Pi J*. Deficiency of long isoforms of Nfe2l1 sensitizes MIN6 pancreatic β cells to arsenite-induced cytotoxicity. Toxicol Appl Pharmacol. 2017; 329:67-74. IF=3.79121.Fu J, Cui Q, Yang B, Hou Y, Wang H, Xu Y, Wang D, Zhang Q, Pi J*. The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response. Food Chem Toxicol. 2017; 100:161-167. IF=3.778
22.Wu R, Wu X, Wang H, Fang X, Li Y, Gao L, Sun G, Pi J*, Xu Y*. Strain differences in arsenic-induced oxidative lesion via arsenic biomethylation between C57BL/6J and 129X1/SvJ mice. Sci Rep. 2017 Mar 17;7:44424. doi: 10.1038/srep44424.
23.Zhu J, Wang H, Chen F, Fu J, Xu Y*, Hou Y, Kou HH, Zhai C, Zhang Q, Andersen ME , Pi J*. An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and potential applications in cancer therapy. Free Radic Biol Med. 2016; 99: 544-556. IF=5.606
24.Fu J, Hou Y, Xue P, Wang H, Xu Y, Qu W, Zhang Q, Pi J*. Nrf2 in Type 2 diabetes and diabetic complications: Yin and Yang. Current Opinion in Toxicology. 2016; 1:9-19.
25.Chen Y, Xu Y*, Zheng H, Fu J, Hou Y, Wang H, Zhang Q, Yamamoto M, Pi J*. The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study. Biochem Biophys Res Commun. 2016; 478:87-92.
26.Peng H, Wang H, Xue P, Hou Y, Dong J, Zhou T, Qu W, Peng S, Li J, Carmichael PL, Nelson B, Clewell R, Zhang Q, Andersen ME, Pi J*. Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells. Toxicol Appl Pharmacol. 2016; 292:1-7.
27.Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, Yamamoto M, Tong Q, Teng W*, Qu W, Zhang Q, Andersen ME, Pi J*. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015; 22:819-31.
28.Fu J, Zheng H, Wang H, Yang B, Zhao R, Lu C, Liu Y, Hou Y, Xu Y, Zhang Q, Qu W, Pi J*. Protective role of nuclear factor E2-related factor 2 against acute oxidative stress-induced pancreatic β-cell damage. Oxidative Med and Cellular Longevity. 2015; Article ID 639191.
29.Pi J*, Zhang Q, Andersen ME. ROS and antioxidants in pancreatic β-cell function: Yin and Yang. (Book chapter). Systems biology of free radicals and anti-oxidants. Springer-Verlag Berlin Heidelberg. 2014; DOI 10.1007/978-3-642-30018-9_159.
30.Chen Y, Xue P, Hou Y, Zhang H, Zheng H, Zhou T, Qu Q, Teng W*, Zhang Q, Andersen ME, Pi J*. Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes. Toxicol Appl Pharmacol. 2013; 273: 435-441.
31.Lv P, Xue P, Dong J, Peng H, Clewell R, Wang A, Wang Y, Peng Q, Qu W, Zhang Q, Andersen ME, Pi J*. Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages. Toxicol Appl Pharmacol. 2013; 272:697-702.
32.Fu J, Zhang Q, Woods CG, Zheng H, Yang B, Qu W, Andersen ME, Pi J*. Divergent effects of sulforaphane on basal and glucose-stimulated insulin secretion in β-cells: role of reactive oxygen species and induction of endogenous antioxidants. Pharmaceutical Res. 2013; 30:2248–2259.
33.Xue P, Hou Y, Chen Y, Yang B, Fu J, Zheng H, Yarborough K, Woods CG, Liu D, Collins S, Yamamoto M, Zhang Q, Andersen ME, Pi J*. Adipose deficiency of Nrf2 in ob/ob mice results in severe metabolic syndrome. Diabetes. 2013; 62:845-854.
34.Hou Y, Xue P, Woods CG, Wang X, Fu J, Yarborough K, Qu W, Zhang Q, Andersen ME, Pi J*. Association between arsenic suppression of adipogenesis and induction of CHOP10 via the endoplasmic reticulum stress response. Environ. Health Perspect. 2013; 121:237-243.
35.Yang B, Fu J, Zheng H, Xue P, Yarborough K, Woods CG, Hou Y, Zhang Q, Andersen ME, Pi J*. Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage. Toxicol Appl Pharmacol. 2012; 264:315-323.
36.Zhan L, Zhang H, Zhang Q*, Woods CG, Chen Y, Xue P, Dong J, Tokar EJ, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes MP, Andersen ME, Pi J*. Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small cell lung carcinoma cells. Free Radic Biol Med. 2012; 53:758-768.
37.Zhao R, Hou Y, Zhang Q, Woods CG, Xue P, Fu J, Yarborough K, Guan D, Andersen ME, Pi J*. Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes. Environ. Health Perspect. 2012; 4:583-589.
38.Hou Y, Xue P, Bai Y, Liu D, Woods CG, Yarborough K, Fu J, Zhang Q, Sun G, Collins S, Chan JY, Yamamoto M, Andersen ME, Pi J*. Involvement of nuclear factor E2-related factor 2 in transcriptional regulation of CCAAT/enhancer-binding protein β expression in the early stage of adipogenesis. Free Radic Biol Med. 2012; 52:462-472.
39.Xue P, Hou Y, Zhang Q, Woods CG, Yarborough K, Liu H, Sun G, Andersen ME, Pi J*. Prolonged inorganic arsenite exposure suppresses insulin-stimulated AKT S473 phosphorylation and glucose uptake in 3T3-L1 adipocytes: Involvement of the adaptive antioxidant response. Biochem Biophys Res Commun. 2011; 407: 360-365.
40.Zhao R, Hou Y, Xue P, Woods CG, Fu J, Feng B, Guan D, Sun G, Chan JY, Waalkes WP, Andersen ME, Pi J*. Long isoforms of NRF1 contribute to arsenic-induced antioxidant response in human keratinocytes. Environ. Health Perspect. 2011; 119: 56-62.
41.Pi J#,*, Leung L#, Xue P, Wang W, Hou Y, Liu D, Yehuda-Shnaidman E., Lee C, Lau J, Kurtz TW, Chan JY*. Deficiency in the nuclear factor E2-related factor 2 transcription factor results in impaired adipogenesis and protects against diet-induced obesity. J Biol Chem. 2010; 285:9292-300.
42.Fu J, Woods CG, Yehuda-Shnaidman E., Zhang Q, Wong V, Collins S, Sun G, Andersen ME, Pi J*. Arsenic impairs glucose-stimulated insulin secretion in pancreatic beta-cells: involvement of Nrf2-mediated antioxidant response. Environ. Health Perspect. 2010; 118:864-870.
43.Pi J* and Collins S*. ROS and UCP2 in pancreatic β-cell function. Diabetes Obes. Metab. 2010; 12S2:141-148.
44.Pi J*, Freeman ML, Yamamoto M. Nrf2 in toxicology and pharmacology: the good, the bad and the ugly? (Editorial) Toxicol Appl Pharmacol. 2010; 244: 1-3.
45.Pi J*, Zhang Q, Fu J, Woods CG, Collins S, Andersen ME. ROS signaling and oxidative stress in pancreatic beta-cell function. Toxicol Appl Pharmacol. 2010; 244:77-83.
46.Woods CG, Fu J, Pluta L, Yang L, Zhang Q, Thomas RS, Mckee RH, Andersen ME, Pi J*. Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicol Appl Pharmacol. 2009; 238:27-29.
47.Pi J*, Bai Y, Daniel K, Dianxin Liu, Edelstein D, Brownlee M, Corkey BE, Collins S*. Persistent oxidative stress due to absence of UCP2 associated with impaired pancreatic beta-cell function. Endocrinology. 2009; 150:3040-3048.
48.Pi J*, Diwan BA, Qu W, Liu J, Sun Y, Miroslav Styblo, Waalkes MP*. Arsenic-induced malignant transformation of human keratinocytes: involvement of Nrf2. Free Radic Biol Med. 2008; 45:651-658.
49.Pi J*, Zhang Q, Wong V, Woods C, Collins S, Andersen ME. Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid. Toxicol Appl Pharmacol. 2008; 226:236-43.
50.Pi J*, Bai Y, Zhang Q, Floering LM, Wong V, Daniel K, Reece JM, Deeney JT, Corkey BE, Collins S. Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes. 2007; 56:1783-1791.
51.Pi J*, Bai Y, Reece JM, William J, Liu D, Freeman ML, Fahl WE, Shugar D, Liu J, Qu W, Collins S, Waalkes MP. Molecular mechanism of Nrf2 activation and degradation: role of sequential phosphorylation by protein kinase CK2. Free Radic Biol Med. 2007; 42:1797-806.
52.Pi J, Yamauchi H, Sun G, Yoshida T, Aikawa H, Fujimoto W, Iso H, Cui R, Waalkes MP, Kumagai Y. Vascular dysfunction in patients with chronic arsenosis can be reversed by reduction of arsenic exposure. Environ. Health Perspect. 2005; 113:339-341.
53.Pi J, He Y, Bortner C, Huang J, Liu J, Zhou T, Qu W, North SL, Kasprzak KS, Diwan BA, Chignell CF, Waalkes MP. Low level, long-term inorganic arsenite exposure causes generalized resistance to apoptosis in cultured human keratinocytes: potential roles in skin co-carcinogenesis. Int J Cancer. 2005; 116:20-26.
54.Pi J, Qu W, Reece JM, Kumagai Y, Waalkes MP. Transcription factor Nrf2 activation by inorganic arsenic in cultured keratinocytes: Involvement of hydrogen peroxide. Exp Cell Biol. 2003; 290:234-245.
55.Pi J, Horikuchi S, Sun Y, Nikaido M, Shimojo N, Hayashi T, Yamauchi H, Itoh K, Yamamoto M, Sun G, Waalkes MP, Kumagai Y. A potential mechanism for the impairment of nitric oxide formation caused by prolonged oral exposure to arsenate in rabbits. Free Radic Biol Med. 2003; 35:102-13.
56.Pi J, Yamauchi H, Kumagai Y, Sun G, Yoshida T, Aikawa H, Hopenhayn-Rich C, Shimojo N. Evidence for induction of oxidative stress caused by chronic exposure of Chinese residents to arsenic contained in drinking water. Environ. Health Perspect. 2002; 110:331-336.
57.Pi J, Kumagai Y, Shimojo N. Improved method for simultaneous determination of L-arginine and its mono- and dimethylated metabolites in biological samples by high-performance liquid chromatography. J Chromatogr B. 2000; 742:199-203.
58.Pi J, Kumagai Y, Sun G, Yamauchi H, Yoshida T, Iso H, Endo A, Yu L, Yuki K, Miyauchi T, Shimojo N. Decreased serum concentrations of nitric oxide metabolites among Chinese in an endemic area of chronic arsenic poisoning in Inner Mongolia. Free Radic Biol Med. 2000; 28:1137-42.
教材：
2013年 全国高等教育医学数字化规划教材（国家医学电子书包） 《预防医学》副主编。
2015-2019年 国家医师资格考试模拟试卷（公共卫生职业医师），人民卫生出版，主编
2015-2019年 国家医师资格考试模拟试卷（公共卫生职业助理医师），人民卫生出版社，主编
期刊：
2019-至今：Toxicology and Applied Pharmacology 专刊客座主编
2017-2018：Toxicology and Applied Pharmacology 专刊客座主编
2013-至今：Toxicology and Applied Pharmacology 副主编
2016-至今：Toxicology Reports 副主编
2012-2013年：Oxidative Medicine and Cellular Longevity 专刊客座主编
2011-2013年：Chemical Research in Toxicology 编委
2009-2010年：Toxicology and Applied Pharmacology 专刊客座主编
2008-2012年：Toxicology and Applied Pharmacology 编委
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