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个人简介

教育经历 1994 - 1998 南昌大学,生物工程,学士 1998 - 2001 中国农业大学,生物化学与分子生物学,硕士 2002 - 2006 美国康涅狄格大学,植物科学, 博士 工作经历 2001 - 2002 研究助理中国,中科院北京基因组研究所 2002 - 2006 研究生研究助理,美国康涅狄格大学 2007 - 2011 博士后, 美国普渡大学 2011 - 2018 植物学研究员, 美国普渡大学 2018.1- 研究员(教授)中科院华南植物园, 研究组组长

研究领域

是植物细胞结构和功能的分子机理。特别是细胞壁和细胞膜在植物生长、矿物质营养的吸收和储存以及胁迫反应中的作用。植物细胞壁和细胞膜是植物细胞最外的两层细胞结构,具有细胞保护、胞内外转运、信号转导和细胞生长等多种重要功能。我将利用拟南芥、水稻和大豆等作物进行细胞壁在细胞伸长过程的合成、分解和分泌调控机制的研究;以及细胞壁和细胞膜在生物和非生物胁迫反应中的作用的研究。

近期论文

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Shiga TM, Xiao W, Yang H, Zhang X, Olek AT, Donohoe BS, Liu J, Makowski L, Hou T, McCann MC, Carpita NC, Mosier NS. (2017) Enhanced rates of enzymatic saccharification and catalytic synthesis of biofuel substrates in gelatinized cellulose generated by trifluoroacetic acid. Biotechnol Biofuels. 10:310. doi: 10.1186/s13068-017-0999-2 Kong Q, Ma W, Yang H, Ma G, Mantyla JJ, Benning C. (2017) The Arabidopsis WRINKLED1 transcription factor affects auxin homeostasis in roots. J. of Experimental Botany. 68: 4627-4634. Sun L-J, Xie Y, Yan Y-F, Yang H, Gu H-Y, Bao N. (2017) Paper-based analytical devices for direct electrochemical detection of free IAA and SA in plant samples with the weight of several milligrams. Sensors and Actuators B: 247: 336-342. Yang H, Wei H, Ma G, Antunes M, Cox J, Zhang X, Liu X, Himmel ME, Tucker MP, McCann MC, Murphy AS, Peer WA. (2016) Cell wall targeted in planta delivery of iron enhances both biomass conversion and nutrition in Arabidopsis and rice. Plant Biotechnology J. 14(10): 1998-2009. Wei H*, Yang H*, Ciesielski PN, Donohoe BS, McCann MC, Murphy AS, Peer WA, Ding S-Y, Himmel ME, Tucher MP. (2014) Transgenic ferritin overproduction largely enhances thermochemical pretreatments in Arabidopsis. Biomass and Bioenergy. 72: 55-56 (*equal contribution) Yang H, Zhang X, Gaxiola RA, Xu G, Peer WA, Murphy AS. (2014) Overexpression of the Arabidopsis proton-pyrophosphatase AVP1 enhances transplant survival, root mass, and fruit development under limiting phosphorus conditions. J. of Experimental Botany. 65: 3045-3053. Yang H, Richter GL, Wang X, Mlodzińska E, Carraro N, Lin JE, Chao D, Peer WA, Murphy AS. (2013) Sterols and sphingolipids differentially function in trafficking of the Arabidopsis ABCB19 auxin transporter. Plant J. 74(1):37-47. Christie JM*, Yang H*, Richter G*, Sullivan S*, Thomson CE, Lin J, Titapiwatanakun B, Ennis M, Kaiserli E, Lee OR, Adamec J, Peer WA, Murphy AS. (2011) phot1 inhibition of ABCB19 primes lateral auxin fluxes in the shoot apex required for phototropism. PloS Biology. 9: e1001076. (*equal contribution) Yang H, Murphy AS. (2009) Functional expression and characterization of Arabidopsis ABCB, AUX1 and PIN auxin transporters in Schizosaccharomyces pombe. Plant J. 59: 179-91. Yang H, Knapp J, Koirala P, Rajagopal D, Peer WA, Silbart LK, Murphy A, Gaxiola RA. (2007) Enhanced phosphorus nutrition in monocots and dicots over-expressing a phosphorus-responsive type I H+-pyrophosphatase. Plant Biotechnol J. 5: 735-45. Li J*, Yang H*, Peer WA, Richter G, Blakeslee JJ, Bandyopadhyay A, Titapiwantakun B, Undurraga S, Khodakovskaya M, Krizek B, Murphy A, Gilroy S, Gaxiola RA ( 2005) Arabidopsis H+-PPase AVP1 regulates auxin mediated organ development. Science 310: 121-125. (*equal contribution) Yang H, Murphy AS. (2013) Membrane preparation, sucrose density gradients and two-phase Separation Fractionation from Five-day-old Arabidopsis seedlings. Bio-Protocol. 3: e1014. Kube? M*, Yang H*, Richter GL*, Cheng Y, Wang X, Mlodzińska E, Carraro N, Titapiwatanakun B, Petrá?ek J, Za?ímalová E, Hoyerová K, Peer WA, Murphy AS. (2012) The Arabidopsis concentration-dependent influx/efflux transporter ABCB4 regulate cellular auxin levels in the root epidermis. Plant J. 69: 640-54. (*equal contribution) Dong J, Pineros MA, Li X, Yang H, Liu Y, Murphy AS, Kochian LV, Liu D. (2016) An Arabidopsis ABC transporter mediates phosphate deficiency-induced remodeling of root architecture by modulating iron homeostasis in roots. Molecular Plant. 10(2):244-259. Lin CY, Jakes JE, Donohoe BS, Ciesielski PN, Yang H, Gleber SC, Vogt S, Ding SY, Peer WA, Murphy AS, McCann MC, Himmel ME, Tucker MP, Wei H. (2016) Directed plant cell-wall accumulation of iron: embedding co-catalyst for efficient biomass conversion. Biotechnol Biofuels. 21;9:225 Kriegel A, Andrés Z, Medzihradszky A, Krüger F, Scholl S, Delang S, Patir-Nebioglu MG, Gute G, Yang H, Murphy A, Peer W, Pfeiffer A, Krebs M, Lohmann J, and Schumacher K. (2015) Job-sharing in the endomembrane system: Vacuolar acidification requires the combined activity of V-ATPase and V-PPase. Plant Cell. 27: 3383-3396. Tsuda E*, Nishimura T*, Yang H*, Yukiko Uehara, Tatsuya Sakai, Masahiko Furutani, Koshiba Tomokazu, Hiroshi Nozaki, Angus Murphy, Ken-ichiro Hayashi. (2011) Alkoxy-auxins are selective inhibitors of auxin transport mediated by PIN, ABCB, and AUX1 transporters. J Biol. Chem. 286:2354-64. (*equal contribution) Sun L-J, Feng Q-M, Yan Y-F, Pan Z-Q, Li X-H, Song F-M, Yang H, Xu J-J, Bao N, Gu H-Y. (2014) Paper-based electroanalytical devices for in situ determination of salicylic acid in living tomato leaves. Biosensors and Bioelectronics 60C: 154-160. Péret B, Swarup K, Ferguson A, Seth M, Yang Y, Dhondt S, James N, Casimiro I, Perry P, Syed A, Yang H, Reemmer J, Venison E, Howells C, Perez-Amador MA, Yun J, Alonso J, Beemster GT, Laplaze L, Murphy A, Bennett MJ, Nielsen E, Swarup R. (2012) AUX/LAX genes encode a family of auxin influx transporters that perform distinct functions during Arabidopsis development. Plant Cell. 24: 2874-85. Hildreth SB, Gehman E, Yang H, Lu R-H, Sandoe JL, Yu S, Okumoto S, Murphy AS, Jelesko JG. (2011) Tobacco nicotine uptake permease (NUP1) affects alkaloid metabolism. Proc. Natl. Acad. Sci USA. 108:18179-84. Undurragaa SF, Santosg MP, Paez-Valenciag J, Yang H, Hepler PK, Facanhaf AR, Hirschid KD, Gaxiola RA. (2012) Arabidopsis sodium dependent and independent phenotypes triggered by H+-PPase up-regulation are SOS1 dependent. Plant Science. 183: 96?05. Peer WA, Blakeslee JJ, Yang H, Murphy AS. (2011) Seven things we think we know about auxin transport. Mol. Plant. 4: 487-504. Bailly A, Yang H, Martinoia E, Geisler M, Murphy AS. (2011) Plant lessons: exploring ABCB functionality through structural modeling. Front. Plant Sci. 2: 108. R??i?ka K, Strader LC, Bailly A, Yang H, Blakeslee J, Langowski L, Nejedlá E, Fujita H, Ito H, Syōno K, Hejátko J, Gray WM, Martinoia E, Geisler M, Bartel B, Murphy AS, Friml J. (2010) Arabidopsis PIS1 encodes the ABCG37 transporter of auxinic compounds including the auxin precursor indole-3-butyric acid. Proc. Natl. Acad. Sci USA. 107:10749-53. Za?ímalová E, Murphy AS, Yang H, Hoyerová K, Ho?ek P. (2010) Auxin transporters: Why so many. Cold Spring Harbor Perspectives in Biology. 2: a001552. Titapiwatanakun B, Blakeslee JJ, Bandyopadhyay A, Yang H, Mravec J, Sauer M, Cheng Y, Adamec J, Nagashima A, Geisler M, Sakai T, Friml J, Peer WA, Murphy AS. (2009) ABCB19/PGP19 stabilises PIN1 in membrane microdomains in Arabidopsis. Plant J. 57: 27-44. Park S, Li J, Pittman JK, Berkowitz GA, Yang H, Undurraga S, Morris J, Hirschi KD, Gaxiola RA. (2005) Up-regulation of a vacuolar H+-PPase as a strategy to engineer drought-resistant crop plants. Proc. Natl. Acad. Sci USA 102: 18830-18835.

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