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个人简介

1986年毕业于华西医科大学药学院获理学学士学位,1989年获理学硕士学位,同年分配至中国医学科学院药物研究所工作。1994年破格晋升副研究员,1997年破格晋升研究员。

研究领域

1. 基于新颖靶点的抗肿瘤及代谢性疾病创新药物发现及构效关系研究; 2. 基于天然产物有效成分结构改造的创新药物研究; 3. 重要非专利药物开发及质量提升研究.

近期论文

查看导师最新文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

1. Wenxuan Zhang, Jun Wu, Bo Li, Hongna Wu, Liu Wang, Jie Hao, Song Wu* and Qi Zhou*. Structure–activity & structure–toxicity relationship study of salinomycin diastereoisomers and their benzoylated derivatives . Organic & Biomolecular Chemistry, 2016, 14, 2840 - 2845. 2. Wenxuan Zhang,a Jun Wu,b Bo Li,a Jie Xia,a Hongna Wu,a Liu Wang,b Jie Hao,b Qi Zhoub and Song Wu*, a Synthesis and biological activity evaluation of 20-epi-salinomycin and its 20-O-acyl derivatives, RSC Adv., 2016,6, 41885-41890. 3. Yan Yang, Hui-Min Wang, Yuan-Feng Tong, Min-Zhi Liu, Ke-Di Cheng, Song Wu* and Wei Wang*, Systems metabolic engineering of Escherichia coli to enhance the production of flavonoid glucuronides, RSC Adv., 2016, 6, 33622–33630. 4. Hongkun Yang, Yuan Feng Tong, Wu Song* . A novel and efficient strategy involving a CuI catalyzed cascade reaction to synthesize acenaphtho[1,2-b]quinolone derivatives. Chinese Chemical Letters, 2016, 27(3), 349-352. 5. Xiaolin Zhang, Jinying Tian, Juan Li, Liwei Huang, Song Wu*, Wei Liang, Liangwei Zhong, Jianping Ye and Fei Ye* ,A novel protein tyrosine phosphatase 1B inhibitor with therapeutic potential for insulin resistance, Br. J. Pharmacol., 2016, 173(12) ,1939–1949. 6. Wen-Xuan Zhang, Hong-Na Wu, Bo Li, Hong-Lin Wu, Dong-Mei Wang, Song Wu *, The Synthesis of the Metabolites of 2′,3′,5′-Tri-O-acetyl-N6-(3-hydroxyphenyl) Adenosine (WS070117) Molecules, 2015, 20, 12114-12124. 7. Ran-Yao Yang, Gang Zhao, Dong-Mei Wang, Xiao-Cong Pang, Shou-BaoWang, Jian-Song Fang,Chao Li, Ai-Lin Liu, Song Wu*, Guan-Hua Du,Pharmacology, Biochemistry and Behavior ,2015, 139,15–26. 8. Qingyun Yang, Hui Qiu, Wei Guo, Dongmei Wang, Xingning Zhou, Dan Xue, Jinlan Zhang, Song Wu * and Yinghong Wang *, Quantitative 1H-NMR Method for the Determination of Tadalafil in Bulk Drugs and its Tablets Molecules 2015, 20, 12114-12124. 9. Hong-Lin Wu, Yuan-Feng Tong & Song Wu* , A convenient semisynthesis of myricetin-3-O-β-d-glucuronide, Journal of Asian Natural Products Research, 2014, 16(5), 522-526. 10. Sheng-Peng Wang, Yuan-Feng Tong, Dong-Mei Wang, Nan Wangb, Zheng Yanb, Ping Huanga, Song Wu*. Synthesis and cytotoxicity evaluation of a novel justicidin G analogue and its phosphate ester., Chinese Chemical Letters. 2014, 25(7) , 1044–1. 11. Lu xiong, Ming-Gang Bi, Song Wu*, Yuan-Feng Tong. Total synthesis of 6′-hydroxyjusticidin A, Journal of Asian Natural Products Research, 2012, 14(4), 322–326. 12. Yang Qingyun, Tong Yuanfeng, Chen Feng, Qi Yan,Li Wei, Wu Song*. Identification and Synthesis of Impurities in Pinocembrin—A New Drug for the Treatment of Ischemic Stroke, Chin. J. Chem. 2012, 30(6), 1315—1319. 13. 张裴,童元峰,王冬梅,吴松*,邻硝基酚醚上的异常取代反应,有机化学,2011,31(2),246-248. 14. Zeqin Lian, Jian Gao, Kai Qu, Jin Li, Linghua Hao, Song Wu *, Haibo Zhu * and Yan Li ,A novel AMPK activator, WS070117, improves lipid metabolism discords in hamsters and HepG2 cells, Lipids in Health and Disease ,2011, 10:67-74. 15. Yuan Feng Tong, Pei Zhang, Feng Chen, Wu Song *, Synthesis and biological evaluation of novel N-(alkoxyphenyl)-aminocarbonylbenzoic acid derivatives as PTP1B inhibitors. Chinese Chemical Letters, 2010,21(12),1415-1418.

学术兼职

兼任国家药典委员会委员、国家食品药品监督管理总局新药审评委员、农业部兽药审评委员、北京药学会理事、药物化学专业委员会副主任委员、《中国新药杂志》编委、《中国药物化学杂志》编委。

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