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招生专业 071006-神经生物学 070302-分析化学 招生方向 神经生物学 神经影像学 分析化学 教育背景 1998-08--2001-06 Yale Medical School 博士后 1998-06--1998-07 U of Kentucky 博士后 1994-09--1998-05 U of Kentucky Ph. D, Physiology 1991-09--1994-05 U of Kentucky Ph. D, Chemistry 1983-09--1986-07 兰州大学 硕士 1979-09--1983-07 兰州大学 学士 工作简历 2007-03~现在, 中科院武汉物理与数学研所, 研究员 2001-07~2007-03,Yale MRRC, 副研究员 1988-08~1990-07,Indiana University, 学习 1986-08~1988-07,兰州大学, 讲师 科研项目 ( 1 ) 嗅觉神经生物学, 主持, 国家级, 2008-01--2011-12 ( 2 ) 嗅觉系统编码机制, 主持, 国家级, 2008-07--2012-06 ( 3 ) 标记和研究记忆相关神经环路的新技术新方法, 主持, 国家级, 2012-01--2015-12 ( 4 ) 嗅觉与饮食状态的关系, 主持, 国家级, 2012-01--2015-12 ( 5 ) 神经回路示踪及其在感知觉等联结图谱研究中的应用, 主持, 部委级, 2013-01--2017-12 ( 6 ) 基于荧光层析/CT双模成像的分子影像关键技术研究, 参与, 国家级, 2012-01--2014-12 ( 7 ) 伪狂犬病毒跨突触传输机制的研究, 参与, 国家级, 2014-01--2017-12 ( 8 ) 灵长类神经回路精细结构成像的新方法和新工具, 主持, 国家级, 2015-01--2019-08 ( 9 ) 神经环路示踪技术平台, 参与, 国家级, 2014-01--2015-12 ( 10 ) 面向情感和记忆神经环路图谱的荧光标记策略研究, 参与, 国家级, 2015-01--2017-12 ( 11 ) “窝/安全空间”记忆形成及其调控恐惧反应的环路机制, 主持, 国家级, 2017-01--2019-12 ( 12 ) 气味相关的两个大脑半球之间的联系, 主持, 国家级, 2016-10--2019-09 ( 13 ) 腹侧被盖区-嗅结节多巴胺能通路在气味偏好形成中的作用, 主持, 国家级, 2018-01--2021-12 参与会议 (1)Translational Neuroscience and Drug development 2015-12-17 (2)Development of Virus-based Tools for Neurocircuit-tracing 2015-10-12

近期论文

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(1) Schizophrenia-like olfactory dysfunction induced by acute and postnatal phencyclidine exposure in rats, Schizophrenia Research, 2018, 其他(合作组作者) (2) Stress Accelerates Defensive Responses to Looming in Mice and Involves a Locus Coeruleus-Superior Colliculus Projection, Current Biology, 2018, 其他(合作组作者) (3) Evaluation of metabolites extraction strategies for identifying different brain regions and their relationship with alcohol preference and gender difference using NMR metabolomics, Talanta, 2018, 通讯作者 (4) Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2018, 通讯作者 (5) RTF: a rapid and versatile tissue optical clearing method, Scientific Reports, 2018, 通讯作者 (6) Whole-brain mapping of the inputs and outputs of the medial part of the olfactory tubercle, Front Neural Circuits, 2017, 通讯作者 (7) NMRSpec: An integrated software package for processing and analyzing one dimensional nuclear magnetic resonance spectra, Chemometrics and Intelligent Laboratory Systems, 2017, 通讯作者 (8) FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7, Neuron, 2017, 其他(合作组作者) (9) Reduced GABAergic transmission in the ventrobasal thalamus contributes to thermal hyperalgesia in chronic inflammatory pain, Scientific Reports, 2017, 第 8 作者 (10) Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice, Molecular Therapy, 2017, 其他(合作组作者) (11) Specific patterns of spinal metabolites underlying α-Me-5-HT-evoked pruritus compared with histamine and capsaicin assessed by proton nuclear magnetic resonance spectroscopy, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 第 8 作者 (12) Pseudo-typed Semliki Forest virus delivers EGFP into neurons, journal of neurovirology, 2017, 第 4 作者 (13) 哺乳动物嗅球的神经网络, 生命科学, 2017, 通讯作者 (14) Activation of the dopaminergic pathway from VTA to the medial olfactory tubercle generates odor-preference and reward, eLife, 2017, 通讯作者 (15) Activity patterns elicited by airflow in the olfactory bulb and their possible functions, Journal of Neuroscience, 2017, 通讯作者 (16) Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129, Molecular Neurodegeneration, 2017, 通讯作者 (17) Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats, Oncotarget, 2017, 通讯作者 (18) A Central Amygdala-Substantia Innominata Neural Circuitry Encodes Aversive Reinforcement Signals, Cell Reports, 2017, 第 8 作者 (19) The interhemispheric CA1 circuit governs rapid generalisation but not fear memory, Nature Communications, 2017, 第 8 作者 (20) Ablation of TFR1 in Purkinje cells inhibits mGlu1 trafficking and impairs motor coordination, but not autistic-like behaviors, Journal of Neuroscience, 2017, 第 9 作者 (21) A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behavior, Nature Communications, 2017, 第 10 作者 (22) Chemical reactivation of resin-embedded pHuji adds red for simultaneous two-color imaging with EGFP, Biomedical Optics Express, 2017, 其他(合作组作者) (23) Brain-wide map of projections from mice ventralsubiculum,, Neuroscience Letters, 2016, 通讯作者 (24) A single adaptive point mutation in Japanese encephalitis virus capsid is sufficient to render the virus as a stable vector for gene delivery, Virology, 2016, 通讯作者 (25) Laterodorsal tegmentum interneuron subtypes oppositely regulate olfactory cue-induced innate fear, Nat Neurosci, 2016, 第 4 作者 (26) Opposite monosynaptic scaling of BLP-vCA1 inputs governs hopefulness- and helplessness-modulated spatial learning and memory, Nat Commun, 2016, 第 4 作者 (27) Processing of visually-evoked innate fear by a non-canonical thalamic pathway, Nature Communication, 2015, 通讯作者 (28) Quantitative proteomics reveals olfactory input-dependent alterations in the mouse olfactory bulb proteome, Journal of Proteomics, 2014, 通讯作者 (29) Complex relationship between BOLD-fMRI and electrophysiological signals in different olfactory bulb layers , Neuroimage, 2014, 通讯作者 (30) Lateral entorhinal modulation of piriform cortical activity and fine odor discrimination, J. Neurosci, 2013, 通讯作者 (31) Amyloid-beta deposition and olfactory dysfunction in an Alzheimers disease model, J. Alzheimers Dis., 2013, 通讯作者 (32) Roles of GSK3 beta in odor habituation and spontaneous neural activity of the mouse olfactory bulb, PLoS One., 2013, 通讯作者 (33) Numerical simulation of airway dimension effects on airflow patterns and odorant deposition patterns in the rat nasal cavity, PLoS One., 2013, 通讯作者 (34) Development- and activity-dependent expression of clusterin in the mouse olfactory bulb, Int. J. Dev. Neurosci., 2013, 第 4 作者 (35) Deficits of peripheral olfactory inputs reduce cell proliferation in the adult subventricular and subgranular zones, Neurosci Lett., 2013, 第 4 作者 (36) Guanylyl Cyclase-C Modulates Midbrain Dopamine Neurons and its Loss Produces ADHD-like Behavior in Mice, science, 2011, 通讯作者 (37) Brain-state-independent neural representation of peripheral stimulation in rat olfactory bulb, PNAS, 2011, 通讯作者 (38) State-dependent coherences between the olfactory bulbs for delta and theta oscillations, Neuroscience Letters, 2010, 通讯作者 (39) Application of MRi in the olfactory system of small animals, Advances in Biochemistry and Biophysics, 2009, 通讯作者 (40) Database analyzing and comparing rodent fMRI odor maps, Neuroinformatics, 2007, 第 2 作者 (41) Reproducibility of Odor Maps by fMRI in Rodents, Neuroimage, 2006, 通讯作者 (42) Odor maps of aldehydes and esters revealed by fMRI in the glomerular layer of the mouse olfactory bulb, PNAS, 2003, 第 1 作者 (43) That’s your left foot and , Trends in Neuroscience, 2001, 通讯作者 (44) Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI, PNAS, 2000, 第 1 作者 (45) A lobster phospholipase C-β that associates with G-proteins in response to odorants, Journal of Neuroscience, 1999, 第 1 作者 (46) A unique urinary constituent,6-hydroxy- 6-methyl-3- heptanone,is a pheromone that accelerates puberty in female mice, Chemical Biology, 1999, 通讯作者

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