个人简介

学历简介： 博士 2008-8 至 2011-12 香港中文大学 硕士 2005-9 至 2008-7 华南理工大学 学士 2001-9 至 2005-7 华南理工大学 工作经历： 2020-1 至 现在 汕头大学 理学院 生物系 教授 2012年1月 至 2019年12月 江南大学 生物工程学院 讲师-副教授 2014年6月 至 2016年1月 欧洲科学院苏宝连院士课题组 博士后

研究领域

发酵工程，食品科学与生物技术方向的研究(1)食药两用真菌（红曲、牛樟芝、桑黄、桦褐孔菌等）发酵合成活性产物的研究;(2)微藻复合材料&高附加值应用；(3)食品/农业废弃物的生物综合利用

承担项目： [ 1 ] 国家重点研发计划-子课题（主持） 红曲黄色素的工业化生产及稳态化技术研究；(编号：2016YFD0400802)， [ 2 ] 国家自然科学基金（主持） 樟芝菌丝体安卓奎诺尔生物合成的调控机理研究；(编号：21306065)， [ 3 ] 江苏省自然科学基金（主持） 樟芝特有活性物质Antroquinonol的分子合成及调控应答机制研究；(编号：BK20181348)， [ 4 ] 江苏省自然科学基金（主持） 基于蛋白质组学的樟芝液态发酵活性代谢产物的生物合成机制研究；(编号：BK20130134)， [ 5 ] 江苏省“六大人才高峰”高层次人才项目（主持） (编号：SWYY-211)， [ 6 ] 中央高校基本科研专项资金（主持） 液态发酵樟芝菌丝体高产活性多糖的研究； [ 7 ] 北京市食品添加剂工程技术研究中心开放课题（主持） [ 8 ] 企业横向合作项目（主持） 樟芝活性产物的检测、分析和纯品制备技术； [ 9 ] 企业横向合作项目（主持） 红曲黄色素提取精制技术的研究开发； [ 10 ] FOTOBIOMAT欧盟项目（参与） 微藻生命复合材料的制备及其应用；

近期论文

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[ 1 ] Bo-Bo Zhang*, Li Wang, Valérie Charles, Joanna C. Rooke, Bao-Lian Su*；Robust and biocompatible hybrid matrix with controllable permeability for microalgae encapsulation；ACS Applied Materials & Interfaces, 2016, 8: 8939–8946； [ 2 ] Bo-Bo Zhang*, Yu-Yan Guan, Peng-Fei Hu, Lei Chen, Gan-Rong Xu, Liming Liu, Peter C.K. Cheung；Production of bioactive metabolites by submerged fermentation of the medicinal mushroom Antrodia cinnamomea: recent advances and future development；Critical Reviews in Biotechnology, 2019, 39, 541-554； [ 3 ] Bo-Bo Zhang, Peter C K Cheung*；A mechanistic study of the enhancing effect of Tween 80 on the mycelial growth and exopolysaccharide production by Pleurotus tuber-regium；Bioresource Technology, 2011, 102: 8323–8326； [ 4 ] Li Wang, Zhi-Yi Hu, Xiao-Yu Yang*, Bo-Bo Zhang*, Wei Geng, Gustaaf Van Tendelooce, Bao-Lian Su*；Polydopamine nanocoated whole-cell asymmetric biocatalyst；Chemical Communications, 2017, 53, 6617–6620； [ 5 ] Peng-Fei Hu, Jing Huang, Lei Chen, Zhongyang Ding, Liming Liu, Istva?n Molna?r*, and Bo-Bo Zhang*；Oxidative stress induction is a rational strategy to enhance the productivity of Antrodia cinnamomea fermentations for the antioxidant secondary metabolite antrodin C；Journal of Agricultural and Food Chemistry, 2020, 68: 3995–4004； [ 6 ] Bo-Bo Zhang*, Peng-Fei Hu, Jing Huang, Yong-Dan Hu, Lei Chen, Gan-Rong Xu；Current advances on the structure, bioactivity, synthesis and metabolic regulation of novel ubiquinone derivatives in the edible and medicinal mushroom Antrodia cinnamomea；Journal of Agricultural and Food Chemistry, 2017, 65, 10395–10405； [ 7 ] Jun Lv, Gao-Fei Qian, Lei Chen, Huan Liu, Hai-Xiao Xu, Gan-Rong Xu, Bo-Bo Zhang*, Chan Zhang*；Efficient biosynthesis of natural yellow pigments by Monascus purpureus in a novel integrated fermentation system；Journal of Agricultural and Food Chemistry, 2018, 66: 918?925； [ 8 ] Bo-Bo Zhang, Peter C K Cheung*；Use of stimulatory agents to enhance the production of bioactive exopolysaccharide from Pleurotus tuber-regium by submerged fermentation；Journal of Agricultural and Food Chemistry, 2011, 59: 1210-1216； [ 9 ] Bo-Bo Zhang, Lei Chen, Peter C K Cheung*；Two-dimensional gel electrophoresis analysis of mycelial cells treated with Tween 80: Differentially expressed protein related to enhanced metabolite production；Journal of Agricultural and Food Chemistry, 2012, 60: 10585–10591； [ 10 ] Bo-Bo Zhang, Jing Cheng, Wen-Yong Lou, Pan Wang, Min-Hua Zong*；Efficient anti-Prelog enantioselective reduction of acetyltrimethylsilane to (R)-1-trimethylsilylethanol by immobilized Candida parapsilosis CCTCC M203011 cells in ionic liquid-based biphasic systems；Microbial Cell Factories, 2012, 11: 108–120； [ 11 ] Yong-Dan Hu, Bo-Bo Zhang*, Gan-Rong Xu, Xiang-Ru Liao*, Peter C.K. Cheung；A mechanistic study on the biosynthetic regulation of bioactive metabolite Antroquinonol from edible and medicinal mushroom Antrodia camphorata；Journal of Functional Foods, 2016, 25: 70–79； [ 12 ] Yong-Dan Hu, Huan Zhang, Rui-Qiu Lu, Xiang-Ru Liao, Bo-Bo Zhang*, Gan-Rong Xu*；Enabling the biosynthesis of Antroquinonol in submerged fermentation of Antrodia camphorata；Biochemical Engineering Journal, 2014, 91: 157-162； [ 13 ] Huan Zhang, Yong-Dan Hu, Rui-Qiu Lu, Yong-jun Xia, Bo-Bo Zhang*, Gan-Rong Xu*；Integrated strategy of pH?shift and glucose feeding for enhanced production of bioactive Antrodin C in submerged fermentation of Antrodia camphorata；Journal of Industrial Microbiology & Biotechnology, 2014, 41: 1305–1310； [ 14 ] Bo-Bo Zhang, Li-Ping Lu, Gan-Rong Xu*；Why solid-state fermentation is more advantageous over submerged fermentation for converting high concentration of glycerol into Monacolin K by Monascus purpureus 9901: A mechanistic study；Journal of Biotechnology, 2015, 206, 60–65； [ 15 ] Jun Lv, Bo-Bo Zhang*, Xiao-Dong Liu, Chan Zhang, Lei Chen, Gan-Rong Xu, Peter C.K. Cheung；Enhanced production of natural yellow pigments from Monascus purpureus by liquid culture: The relationship between fermentation conditions and mycelial morphology；Journal of Bioscience and Bioengineering, 2017, 124, 452–458；