李鹏 - 澳门大学 - 中华医药研究院

个人简介

Academic Qualifications BSc, MSc, Chengdu University of TCM MSc, PhD, University of Macau Teaching Bsc Courses Orgainic Chemistry (BIOB115) Wonders in Life Science and Health: Biomedical Science (ICMS212) MSc Courses Quality control (MCMC100) Pharmacology and Safety Evaluation (MCMC101) PhD Courses Advanced quality control of herbal medicine (CMED802)

研究领域

Key techniques of quality control and safety evaluation of Chinese medicines. R&D of new products and new dosage forms of Chinese medicines.

近期论文

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Book Chapters 1.P Li, SP Li. Pressurized Liquid Extraction in Phytochemical Analysis. In Reviews in Pharmaceutical and Biomedical Analysis. Paraskevas D. Tzanavaras & Constantinos K. Zacharis, Ed. Bentham Science Publishers, Inc.: Netherlands, 2010. 2.P Li, YT Wang, SP Li. DanShen (丹参，Salvia miltiorrhiza). In Pharmacological Activity-Based Quality Control of Chinese Herbs. Shaoping Li, Ed. Nova Science Publishers, Inc.: New York, 2008. Journal Papers 1.Shen DY, Wei JC, Wan JB, Huang XJ, Xiang C, Li BC, Zhang QW, Wang YT, Li P*. Four new C21 steroidal glycosides from Cynanchum otophyllum Schneid. Phytochem. Lett. 2014, in press. 2.Zhu HL, Wan JB, Wang YT, Li BC, Xiang C, He J, Li P*. Medicinal compounds with antiepileptic/anticonvulsant activities. Epilepsia 2014, 55 (1): 3-16. 3.Xiang C, Li F, Zhang LD, Li BC, He J, Qin Y, Wan JB, Wang YT, Li P*. Determination of radical scavengers from Salvia plants by HPLC. Anal. Lett. 2014, 47 (1): 1-13. 4.Ni N, Liu Q, Ren H, Wu D, Luo C, Li P, Wan JB, Su HX. Ginsenoside Rb1 protects rat neural progenitor cells against oxidative injury. Molecules. 2014, 19 (3): 3012-3024. 5.Zhang XJ, Huang LL, Su HX, Chen YX, Huang J, He CW, Li P, Yang DZ, Wan JB. Characterizing plasma phospholipid fatty acid profiles of polycystic ovary syndrome patients with and without insulin resistance using GC-MS and chemometrics approach. J. Pharm. Biomed. Anal. 2014, 95: 85-92. 6.Zhu LP, Xiang C, Zhuang WT, He J, Li P*, Li BC. Screening the anti-angiogenic constituents from Salvia przewalskii Maxim and quantitative analysis of them. Asian. J. Chem. 2013, 25 (15): 8517-8521. 7.Wan JB, Li P, Yang RL, Zhang QW, Wang YT. Separation and purification of 5 saponins from Panax notoginseng by preparative high-performance liquid chromatography. J. Liq. Chromatogr R&T. 2013, 36 (13): 406-417. 8.Chen YG, Li P, Li P, Yan R, Zhang XQ, Wang Y, Zhang XT, Ye WC, Zhang QW. Alpha-Glucosidase inhibitory effect and simultaneous quantification of three major flavonoid glycosides in microctis folium. Molecules. 2013, 18 (4): 4221-4232. 9.Zhang XJ, Huang LL, Cai XJ, Li P, Wang YT, Wan JB. Fatty acid variability in three medicinal herbs of Panax species. Chem. Cent. J. 2013, 7 (1): 12-19. 10.Ni N, Hu YH, Ren HX, Luo CM, Li P, Wan JB, Su HX. Self-assembling peptide nanofiber scaffolds enhance dopaminergic differentiation of mouse pluripotent stem cells in 3-dimenstional culture. PLoS ONE 2013, 8 (12): e84504. 11.Chen M, Zhang J, Lai Y, Wang S, Li P, Xiao J, Fu C, Hu H, Wang Y. Analysis of Pogostemon cablin from pharmaceutical research to market performances. Expert Opin. Investig. Drugs. 2013, 22 (2): 245-257. 12.Zhang XJ, Qiu JF, Guo LP, Wang Y, Li P, Yang FQ, Su HX, Wan JB. Discrimination of multi-origin Chinese herbal medicines using gas chromatography-mass spectrometry-based fatty acid profiling. Molecules 2013, 18: 15329-15343. 13.Li F, Zhang LD, Li BC, Yang J, Yu H, Wan JB, Wang YT, Li P*. Screening of free radical scavengers from Erigeron breviscapus using on-line HPLC-ABTS/DPPH based assay and mass spectrometer detection. Free Radic. Res. 2012, 46 (3): 286-294. 14.Zhuang WT, Xiang C, Zhu LP, He J, Li BC, Li P*. 6-Hydroxysugiol isolated from salvia yunnanensis inhibits proliferation and migration of HepG2 cells as well as exhibits potent anti-angiogenic activity. Lat. Am. J. Pharm. 2012, 31 (10): 1457-1463. 15.Wan JB, Zhang QW, Hong SJ, Li P, Li SP, Wang YT. Chemical investigation of saponins in different parts of Panax notoginseng by pressurized liquid extraction and liquid chromatography-electrospray ionization-tandem mass spectrometry. Molecules. 2012, 17 (5): 5836-5853. 16.Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (Danshen) collected from different locations in China. J. Agric. Food Chem. 2009, 57 (15): 6879-6887. 17.Li P, Xu G, Li SP, Wang YT, Fan TP, Zhao QS, Zhang QW. Optimizing ultra-performance liquid chromatographic analysis of 10 diterpenoid compounds in Salvia miltiorrhiza using central composite design. J. Agric. Food Chem. 2008, 56 (4): 1164-1171. 18.Li P, Li SP, Yang FQ, Wang YT. Simultaneous determination of four tanshinones in salvia miltiorrhiza by pressurized liquid extraction and capillary electrochromatography. J. Sep. Sci. 2007, 30 (6): 900-905. 19.Jiang Y, Li P, Li SP, Wang YT, Tu PF. Optimization of pressurized liquid extraction of five major flavanoids from Lysimachia clethroide. J. Pharm. Biomed. Anal. 2007, 43 (1): 341-345. 20.Yang FQ, Li SP, Li P, Wang YT. Optimization of CEC for simultaneous determination of eleven nucleosides and nucleobases in Cordyceps using central composite design. Electrophoresis 2007, 28 (11): 1681-1688. 21.Li P, Li SP, Wang YT. Optimization of CZE for analysis of phytochemical bioactive compounds. Electrophoresis 2006, 27 (23): 4808-4819. 22.Li P, Li SP, Lao SC, Fu CM, Kan Kelvin KW, Wang YT. Optimization of pressurized liquid extraction for Z-ligustilide, Z-butylidenephthalide and ferulic acid in Angelica sinensis. J. Pharm. Biomed. Anal. 2006, 40 (5): 1073-1079. 23.Wan JB, Li P, Li SP, Wang YT, Dong Tina TX, Tsim Karl WK. Simultaneous determination of 11 saponins in Panax notoginseng using HPLC-ELSD and pressurized liquid extraction. J. Sep. Sci. 2006, 29 (14): 2190-2196. 24.Gong YX, Li SP, Wang YT, Li P, Yang FQ. Simultaneous determination of anthraquinones in Rhubarb by pressurized liquid extraction and capillary zone electrophoresis. Electrophoresis 2005, 26 (9): 1778-1782. 25.Li SP, Li P, Lai CM, Gong YX, Kan KW, Dong TX, Tsim WK, Wang YT. Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by pressurised liquid extraction and high-performance liquid chromatography. J. Chromatogr. A 2004, 1036 (2): 239-243. 26.Gong YX, Li SP, Li P, Liu JJ, Wang YT. Simultaneous determination of six main nucleosides and bases in natural and cultured Cordyceps by capillary electrophoresis. J. Chromatogr. A 2004, 1055 (1-2): 215-221. 27.Lao SC, Li SP, Kan KW, Li P, Wan JB, Wang YT, Dong TX, Tsim WK. Identification and quantification of 13 components in Angelica sinensis (Danggui) by gas chromatography–mass spectrometry coupled with pressurized liquid extraction. Anal. Chim. Acta 2004, 526 (2): 131-137. 28.Shen DY, Chen MW, Wang SP, Li P*, Wang YT. Progress in novel drug delivery systems of anti-tumor traditional chinese medicine — blood-activating and stasis-resolving Chinese medicine. World Sci. Technol. – Mod. Tradit. Chin. Med. Mater. Med. (世界科学技术—中医药现代化). 2013, 15 (1): 34-39. 29.Zhuang WT, Zhu LP, Xiang C, He J, Li P, Li BC. Rapid isolation of anti-angiogenic constituents by activity-oriented separation method. Nat Prod Res Dev (天然产物研究与开发). 2013, 25: 370-374. 30.Zhu LP, Xiang C, Zhuang WT, He J, Li P, Li BC. Study on the chemical constituents of Salvia przewalskii Maxim. Nat Prod Res Dev (天然产物研究与开发). 2013, 25: 785-788. 31.Xiang C, Zhu LP, Zhuang WT, Zhang LD, He J, Li P, Li BC. Chemical constituents of stems and leaves of Salvia yunnanensis and their anti-angiogeneic activities. China J. Chin. Mater. Med. (中国中药杂志). 2013, 38 (6): 835-838. 32.Zhang LD, Li F, Zeng LN, Xiang C, Li BC, Li P*. Analysis of chemical components in four Salvia plants by HPLC with column switching. Chin. Trad. Patent Med. (中成药). 2012, 34 (9): 1743-1747. 33.Wang SP, Shen DY, Li P, Chen MW, Wang YT. Progress in novel drug delivery systems of antitumor Chinese medicinals — Qingre Jiedu Chinese medicinals. World Sci. Technol. – Mod. Tradit. Chin. Med. Mater. Med. (世界科学技术—中医药现代化). 2012, 14 (6): 2131-2135. 34.Chen RE, Shen DY, Li P, Wang SP, Hu YY, Chen MW, Wang YT. Systematic study of Chinese medicine herb pairs (Ⅴ) — herb pair of Salvia miltrorrhiza and Panax notoginseng. World Sci. Technol. – Mod. Tradit. Chin. Med. Mater. Med. (世界科学技术—中医药现代化). 2012, 14 (2): 1342-1348. 35.Yin ZH, Sun J, Ding ZJ, Li P. The optimum condit ions for extration of flavonoids and polyphenols from propolis. J. Kunming Med. Univ. (昆明医学院学报). 2011, 12: 8-13. 36.Sun J, Yin ZH, Ding ZJ, Li P. Thermosensitive in situ gel based on poloxamer system containing β-cyclodextrin for sustained release of propolis in vitro. J. Kunming Med. Univ. (昆明医学院学报). 2011, 12: 14-17. 37.Li P, Li SP, Li MY, Wang YT. Research progress on pharmacological effects and mechanisms of Salvia miltiorrhiza on nervous system. Chin. Trad. Herb. Drugs (中草药) 2006, 37: 18-22. 38.Li P, Li SP, Gong YX, Wang YT. Simultaneous determination of ergosterol, nucleosides and their bases from natural and cultured Cordyceps by accelerated solvent extraction and high performance liquid chromatography. Acta Pharm. Sin. (药学学报) 2004, 39 (11): 917-920. 39.Li P, Wang YT, Fu CM, Li SP, Kan KW. Accelerated solvent extraction in quality control of Chinese herb. China J. Chin. Mater. Med. (中国中药杂志) 2004, 29 (8): 723-726. 40.Li P, Wan JB, Li SP, Wang YT. Studies on the accelerated solvent extraction of Panax notoginseng saponins. Chin. J. Nat. Med. (中国天然药物) 2004, 2 (3): 157-161.