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Chen LL*, Li Y*, Chi HL, Liu M, Song YY, Chan TH, Yuan YF, Chow RKK, Fu L, Kong KL, Zhang N, Tong AHY, Kwong DLW, Man K, Lo CM, Lok S, Tenen DG, Guan XY. Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma. Nature Medicine. 2013 Feb;19(2):209-16. (影响因子: 32.621) (*:与第一作者具有同等贡献)
Li Y, Chen L, Chan TH, Guan XY. Hepatocellular Carcinoma: Transcriptome diversity regulated by RNA editing. The International Journal of Biochemistry & Cell Biology. 2013 Aug;45(8):1843-8. (影响因子: 3.247)
Li Y, Chen LL, Chan TH, Liu M, Kong KL, Li Y, Qiu JL, Yuan YF, Guan XY. SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice. Gastroenterology. 2013 Jan;144(1):179-191. (影响因子: 20.773)
Wu B, Zhang D, Nie H, Shen S, Li Y, Li S. Structure of Arabidopsis thaliana N6-methyl-AMP deaminase ADAL with bound GMP and IMP and implications for N6-methyl-AMP recognition and processing. RNA Biol. 2019 Oct;16(10):1504-1512.
Wang Z, Yan M, Li J, Long J, Li Y*, Zhang H*. Dual functions of STAT3 in LPS-induced angiogenesis of hepatocellular carcinoma. Biochim Biophys Acta Mol Cell Res. 2019 Apr;1866(4):566-574. (影响因子: 4.651) (*:共同通讯作者)
Sin STK, Li Y, Liu M, Ma S, Guan XY.TROP-2 exhibits tumor suppressive functions in cervical cancer by dual inhibition of IGF-1R and ALK signaling. Gynecol Oncol. 2019 Jan;152(1):185-193. (影响因子: 4.540)
Li L, Li JC, Yang H, Zhang X, Liu LL, Li Y, Zeng TT, Zhu YH, Li XD, Li Y, Xie D, Fu L, Guan XY. Expansion of cancer stem cell pool initiates lung cancer recurrence before angiogenesis. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):E8948-E8957. (影响因子: 9.504)
Zhao H, Yuan X, Yu J, Huang Y, Shao C, Xiao F, Lin L, Li Y, Tian L. Magnesium-Stabilized Multifunctional DNA Nanoparticles for Tumor-Targeted and pH-Responsive Drug Delivery. ACS Appl Mater Interfaces. 2018 May 9;10(18):15418-15427. (影响因子: 8.097)
Dai Y, Liu L, Zeng T, Liang JZ, Song Y, Chen K, Li Y, Chen L, Zhu YH, Li J, Li Y, Xie D, Yuan YF, Guan XY. Overexpression of MUC13, a Poor Prognostic Predictor, Promotes Cell Growth by Activating Wnt Signaling in Hepatocellular Carcinoma. Am J Pathol. 2018 Feb;188(2):378-391. (影响因子: 4.069)
Yan Q, Jiang L, Liu M, Yu D, Zhang Y, Li Y, Fang S, Li Y, Zhu YH, Yuan YF, Guan XY. ANGPTL1 Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling. Cancer Res. 2017 Nov 1;77(21):5831-5845. (影响因子: 9.130)
Jiang L, Yan Q, Fang S, Liu M, Li Y, Yuan YF, Li Y, Zhu Y, Qi J, Yang X, Kwong DLW, Guan XY. Calcium binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating ERK signaling pathway. Hepatology. 2017 Nov;66(5):1529-1545. (影响因子: 14.079)
Chow RK, Sin ST, Liu M, Li Y, Chan TH, Song Y, Chen L, Kwong DL, Guan XY. AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways. Oncotarget. 2016 Oct 18;8(48):83469-83479. (影响因子: 5.168)
Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY. CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59. (影响因子: 14.079)
Jiang L, Kwong DL, Li Y, Liu M, Yuan YF, Li Y, Fu L, Guan XY. HBP21, a chaperone of heat shock protein 70, functions as a tumor suppressor in hepatocellular carcinoma. Carcinogenesis. 2015 Oct;36(10):1111-20. (影响因子:5.072)
Song Y, Pan G, Chen L, Ma S, Zeng T, Chan HM, Li L, Lian Q, Chow R, Cai X, Li Y, Li Y, Liu M, Li Y, Zhu Y, Wong N, Yuan YF, Pei D, Guan XY. Loss of ATOH8 increases stem cell features of hepatocellular carcinoma cells. Gastroenterology. 2015 Oct;149(4):1068-81. (影响因子: 20.773)
Chan TH, Lin CH, Qi L, Fei J, Li Y, Yong KJ, Liu M, Song Y, Chow RK, Ng VH, Yuan YF, Tenen DG, Guan XY, Chen L. A disrupted RNA editing balance mediated by ADARs in human hepatocellular carcinoma. Gut. 2014 May;63(5):832-43. (影响因子: 17.016)
Liu M, Li Y, Chen L, Chan TH, Song Y, Fu L, Zeng TT, Dai YD, Zhu YH, Li Y, Chen J, Yuan YF, Guan XY. Allele-specific imbalance of oxidative stress-induced growth inhibitor 1 associates with progression of hepatocellular carcinoma. Gastroenterology. 2014 Apr;146(4):1084-96. (影响因子: 20.773 )
Liu L, Dai Y, Chen J, Zeng T, Li Y, Chen L, Zhu YH, Li J, Li Y, Xie D, Yuan YF, Guan XY. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition via Akt/GSK-3β/Snail signaling. Hepatology. 2014 Feb;59(2):531-43. (影响因子: 14.079)
Liu M, Chen LL, Chan TH, Wang J, Li Y, Li Y, Zeng TT, Yuan YF, Guan XY. Serum and glucocorticoid kinase 3 at 8q13.1 promotes cell proliferation and survival in hepatocellular carcinoma. Hepatology. 2012;55:1754-65. (影响因子: 14.079)
Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY. MicroRNA-375 inhibits tumor growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. Gut. 2012 Jan;61(1):33-42. (影响因子: 17.016)
Li J, Lau GK, Chen L, Dong SS, Lan HY, Huang XR, Li Y, Luk JM, Yuan YF, Guan XY. Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression. PLoS One. 2011;6(7):e21816. (影响因子:2.766)
Tang DJ, Dong SS, Ma NF, Xie D, Chen LL, Fu L, Lau SH, Li Y, Li Y, Guan XY. Overexpression of EIF5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma. Hepatology. 2010 Apr;51(4):1255-63 (影响因子: 14.079)
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