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个人简介

工作经历 2013 至今 南方科技大学,生物系,副教授; 2012 香港科技大学,博士后; 2007至2012 美國芝加哥大学分子遗存及细胞生物学系,博士后。 学习经历 2007,香港中文大学生物学博士学位; 2003,香港中文大学生物技术硕士学位; 2001,香港中文大学生物技术学士学位

研究领域

(1) 研究细胞与发育生物学相关课题:主要利用人体细胞及秀丽隐杆线虫研究调控细胞分裂、细胞极性及细胞粘附的分子机理及相关器官发育机制。 (2) 开发荧光纳米探针应用于癌症治疗及检测:通过与化学领域的课题组合作,设计并合成荧光纳米探针,然后利用人体细胞及小鼠模型进行各类治疗及检测癌细胞的应用性研究

近期论文

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1. Lan H*, Wang X*, Jiang L*, Wu J, Wan X, Zeng L, Zhang D, Lin Y, Hou C, Wu S, Tse YC#. (2019) An extracellular matrix protein promotes anillin-dependent processes in the Caenorhabditis elegans germline. Life Science Alliance, DOI:10.26508/lsa.201800152. 2. Yang J, Zhu Y, Tse KW, Zhou X, Chen Y, Tse YC#, Wong KM#, Ho CY#. (2019) Synthesis and study of Au(III)–indolizine derivatives: turn-on luminescence by photo-induced controlled release. Chemical Communication 55:4471-4474. DOI: 10.1039/c8cc10177a. 3. Liao Q, Gong G, Siu SWI, Wong CTT, Yu H, Tse YC, Rádis-Baptista G, Lee SM. (2018) A Novel ShK-Like Toxic Peptide from the Transcriptome of the Cnidarian Palythoa caribaeorum Displays Neuroprotection and Cardioprotection in Zebrafish. Toxins, 10:piiE238. DOI:10.3390/toxins10060238. 4. Li L, Wang S, Lan H, Gong G, Zhu Y, Tse YC#, Wong KM#. (2017) Rhodol Derivatives as Selective Fluorescent Probes for the Detection of HgII Ions and the Bioimaging of Hypochlorous Acid. ChemistryOpen 7: 136-143. DOI: 10.1002/open.201700154. 5. Li L, Wang C, Wu J, Tse YC#, Cai YP, Wong KM#. (2016) A Molecular Chameleon with Fluorescein and Rhodamine Spectroscopic Behaviors. Inorganic Chemistry 55: 205-213. DOI:10.1021/acs.inorgchem.5b02147. 6. Basant A, Lekomtsev S, Tse YC, Zhang D, Longhini KM, Petronczki M, Glotzer M. (2015) Aurora B kinase promotes cytokinesis by inducing centralspindlin oligomers that associate with the plasma membrane. Developmental Cell 33: 204-215. DOI:10.1016/j.devcel.2015.03.015 7. Tse YC*, Werner ME, Longhini MK, Labbe JC, Goldstein B, Glotzer M. (2012) RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4. Molecular Biology of the Cell 23: 4023-4031. 8. Tse YC*, Wang J, Jiang L. (2012) Multivesicular bodies in developing tobacco seed and mung bean are functionally equivalent. Plant Signaling & Behavior 7:1-4. 9. Tse YC*, Piekny A, Glotzer M. (2011) Anillin promotes astral microtubule-directed cortical myosin polarization. Molecular Biology of the Cell 22:3165-3175. 10. Wang J, Tse YC, Hinz G, Robinson DG, Jiang L. (2011) Storage globulins pass through the Golgi apparatus and multivesicular bodies in the absence of dense vesicle formation during early stages of cotyledon development in mung bean. Journal of Experimental Botany 63:1367-1380. 11. Afshar K, Werner ME^, Tse YC^, Glotzer M, Gönczy P. (2010) Regulation of cortical contractility and spindle positioning by the protein phosphatase 6 PPH-6 in one-cell stage C. elegans embryos. Development 137:237-47. (^ these authors contributed equally to this work.) 12. Wang H, Tse YC, Law AH, Sun SS, Sun YB, Xu ZF, Hillmer S, Robinson DG, Jiang L. (2010) Vacuolar sorting receptors (VSRs) and secretory carrier membrane proteins (SCAMPs) are essential for pollen tube growth. The Plant Journal 61:826-838. 13. Tse YC*, Lam SK, Jiang L. (2009) Organelle identification and characterization in plant cells: Using a combinational approach of confocal immunofluorescence and electron microscope. Journal of Plant Biology 52:1-9. 14. Lam SK, Cai Y, Tse YC, Wang J, Law AH, Pimpl P, Chan HY, Xia J, Jiang L. (2009) BFA-induced compartments from the Golgi apparatus and trans-Golgi network/early endosome are distinct in plant cells. The Plant Journal 60:865-881. 15. Lam SK, Tse YC, Miao Y, Li HY, Wang J, Lo SW, Jiang L. (2007) Molecular characterization of plant prevacuolar and endosomal compartments. Journal of Integrative Plant Biology 49:1119-1128. 16. Lam SK, Tse YC, Robinson DG and Jiang L. (2007) Tracking down the elusive early endosome. Trends in Plant Science 12: 497-505. 17. Tse YC*, Lam SK and Jiang L. (2007) Enigmatic Brefeldin A. Plant Signaling & Behavior. Plant Physiology 2: 199-202. 18. Tse YC*, Lo SW, Hillmer S, Dupree P and Jiang L. (2006) Dynamic response of prevacuolar compartments to Brefeldin A in plant cells. Plant Physiology 142:1442-1459. 19. Oliviusson P, Heinzerling L, Hillmer S, Hinz G, Tse YC, Jiang L and Robinson DG. (2006) Plant retromer: identification, localization to the prevacuolar compartment and microvesicles, and preliminary evidence for an interaction with vacuolar sorting receptors. Plant Cell 18:1239-1252. 20. Tse YC*, Mo BX* and Jiang L. (2006) Plant prevacuolar/endosomal compartments. International Review of Cytology 253:95-129. (* these authors contributed equally to this work.)

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