个人简介
2001年7月毕业于大连轻工业学院生物化工专业,获工学学士学位;2006年6月毕业于北京师范大学生物化学与分子生物学专业,获理学博士学位(硕博连读);分别于2009年2月至2009年8月、2012年2月至2013年2月、2013年7月至2014年7月在美国Utah州立大学生物工程系从事访问学者研究。2006年7月起至今任教于东北电力大学。
近期论文
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1.Da-yu Yu*,Fu-chao Xu,Lei Shao,Ji-xun Zhan. Aspecific cytochrome P450 hydroxylase in herboxidiene biosynthesis.Bioorganic & Medicinal Chemistry Letters,2014, 24: 4511-4514.(SCI, IF: 2.420)
2.Da-yu Yu, Fu-chao Xu, Jia-chen Zi, Si-yuan Wang, David Gage, Jia Zeng,Ji-xun Zhan. Engineered production of fungal anticancer cyclooligomer depsipeptidesinSaccharomyces cerevisiae.Metabolic Engineering, 2013, 18(3):60-68.(SCI, IF: 8.258)
3.Da-yu Yu, Fu-chao Xu, David Gage, Ji-xun Zhan. Functional dissectionand module swapping of fungal cyclooligomer depsipeptide synthetases.Chemical Communication, 2013, 49(55):6176-6178.(SCI, IF: 6.718)
4.Da-yu Yu,Fu-chao Xu,Shu-wei Zhang,Lei Shao,Si-yuan Wang,Ji-xun Zhan. Characterizationof a methyltransferase involved in herboxidiene biosynthesis.Bioorganic & Medicinal Chemistry Letters,2013, 23(20): 5667-5670.(SCI, IF: 2.331)
5.Da-yu Yu, Fu-chao Xu, Jonathan Valiente, Si-yuan Wang, Ji-xun Zhan. Anindigoidine biosynthetic gene cluster containing an unusual IndB homologue fromStreptomyces chromofuscusATCC 49982.Journal of industrial microbiology &biotechnology,2013, 40(1): 159-168.(SCI, IF: 2.505)
6.Da-yu Yu*, Fu-chao Xu, Jia Zeng, Ji-xun Zhan.Type IIIpolyketide synthases in natural product biosynthesis.IUBMB Life, 2012, 64(4): 285-295.(SCI, IF: 2.789)
7.Da-yu Yu*, Bo Gao, Meng-yu Yang,Wen-chao Liu and Nan Qiao. The treatment of heterotrophic nitrification-aerobicdenitrifier bacteria loaded with bacterial cellulose membrane to nitrogenous wastewater.Fresenius Environmental Bulletin, 2011, 20(5): 1208-1215.(SCI, IF: 0.641)
8.Da-yu Yu*, Meng-yu Yang, Bo Gao andWen-chao Liu.The disposal of domestic sewage by heterotrophicnitrification-aerobic denitrifierbacteria immobilized with bacterial cellulosemembrane. Fresenius EnvironmentalBulletin, 2011, 20(2): 398-404.(SCI,IF: 0.641)
9.Da-yu Yu, Jia Zeng, Dong Chen andJi-xun Zhan. Characterization and reconstitution of a new fungal type IIIpolyketide synthase fromAspergillusoryzae. Enzyme and Microbial Technology, 2010, 46(7): 575-580.(SCI, IF: 2.592)
10.Da-yu Yu*,Nan Qiao, Ping Liu and Qun Wei.Different regulationmodes of calcineurin regulatory subunit on its catalytic subunit with RII peptideand tau as substrates. Protein and Peptide Letters, 2009, 16(2): 168-172.(SCI, IF: 1.994)
11.Da-yu Yu, Li Tong, Gao-jie Song, Wei-lin Lin, Lai-qunZhang, Wei Bai, He Gong, Yan-xia Yin and Qun Wei.Tau binds both subunits of calcineurin,and binding is impaired by calmodulin.BBA-MolecularCell Research, 2008; 1783(12): 2255-2261.(SCI, IF: 4.808)
12.Da-yu Yu, Jing Luo, Fan Bu, Gao-jieSong, Lai-qun Zhang and Qun Wei. Inhibition of calcineurin by infusion of CsAcauses hyperphosphorylation of tau, accompanied by abnormal behavior in mice.Biological Chemistry, 2006; 387(7): 977-983.(SCI, IF:2.683)
13.Da-yu Yu, Jing Luo, Fan Bu, WenZhang and Qun Wei.Effects of cyclosporin A, FK506 and rapamycinon calcineurin phosphatase activity in mouse brain. IUBMB Life, 2006; 58(7):429-433.(SCI, IF: 2.789)
14.Da-yu Yu*, Mo-jie Sun, Nan Qiao and Qun Wei. Regulations of calcineurinB subunit and calmodulin on calcineurin A subunit with tau and its truncation mutantas substrates.The 2nd International Conferenceon Bioinformatics and Biomedical Engineering, May 2008, Shanghai.(EI收录)
15.于大禹*,尹旭,张静,高波,王刚,曹生现,杨善让,徐志明。基于模拟循环冷却装置的微生物污垢形成的影响因素。化工学报,2011;62(12):3503-3510.(EI收录)
16.于大禹*,张琳颖,高波。异养硝化-好氧反硝化菌异养硝化性能的影响因素。化工进展,2012;31(12):2797-2800.(中文重要)
17.于大禹*,张静,尹旭,王刚,张艳辉,曹生现。循环冷却水管路微生物污垢形成的动态模拟。化工进展,2010;29(11):2193-2197.(中文重要)
18.于大禹*,郭威,张金榜,张贺,杨鹏。好氧反硝化菌的筛选及其脱氮除磷性质的研究。微生物学通报,2009;36 (4): 598-603.(中文核心)
19.于大禹*,门洪,穆胜伟,杨善让。微生物污垢检测技术的特点、现状与发展趋势。微生物学通报,2008;35(12):1955-1960.(中文核心)
20.于大禹*,魏群。钙调磷酸酶对阿尔茨海默病中tau蛋白异常磷酸化的作用。生命的化学,2007;27 (4): 339-340.(中文核心)
学术兼职
1.吉林省生物化学与分子生物学会理事
2.中国生物工程学会会员
3.中国化学会会员
4.中国电机工程学会会员
5.国家自然科学基金项目评审专家