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招生方向 纳米生物医学 生物力学 教育背景 2003-09--2008-07 北京大学医学部 博士 工作简历 2013-06~现在, 国家纳米科学中心, 副研究员 2010-12~2013-05,国家纳米科学中心, 助理研究员 2008-11~2010-11,国家纳米科学中心, 博士后研究 2003-09~2008-07,北京大学医学部, 博士 1994-09~2003-08,山西榆次卫生学校, 教师 1992-10~1994-08,山西榆次使赵卫生院, 医生 教授课程 纳米技术在生物检测中的应用 专利成果 ( 1 ) 一种高通量微流控生物力学长期刺激系统及其应用, 2011, 第 2 作者, 专利号: 2011104046208 ( 2 ) 一种动脉血管模拟微流控装置及其应用, 2011, 第 2 作者, 专利号: 2011104045046 ( 3 ) 一种基于蛋白纤维生成在水凝胶中构建微通道的加工方法, 2012, 第 5 作者, 专利号: 201210086433.4 ( 4 ) 一种用于微流通道的除气泡装置, 2010, 第 2 作者, 专利号: 201010256931.X ( 5 ) 一种能同时施加力学刺激和化学刺激的微流控装置, 2013, 第 3 作者, 专利号: 201310109627.6 ( 6 ) 一种脂质体纳米颗粒及其药物组合物和应用, 2016, 第 3 作者, 专利号: 201611054679.8 ( 7 ) 金纳米簇-脂质体复合颗粒及其制备方法和应用, 2017, 第 3 作者, 专利号: 201710102620.X 发表著作 ( 1 ) 微米尺度细胞图案化及其微环境, Micro-Scale Patterning of Cells and their Environment, Elsevier/Academic Press, 2013-06, 第 1 作者 科研项目 ( 1 ) 微流控动脉粥样硬化症早期体外模型的构建及其在血流动力学致病机制研究方面的应用, 主持, 国家级, 2012-01--2015-12 ( 2 ) 微流控芯片的规模制备, 主持, 国家级, 2013-07--2018-06 ( 3 ) 用于神经信息检测的纳米材料, 参与, 国家级, 2010-01--2015-12 ( 4 ) 基于血流动力学模拟芯片的循环肿瘤细胞生物学特性研究, 主持, 国家级, 2015-01--2018-12 ( 5 ) 基于微流控芯片的神经-肿瘤相互作用研究, 主持, 国家级, 2017-01--2020-12 参与会议 (1)模拟血管动力学环境的微流控芯片构建及其应用 中国生物材料学会2013年大会 郑文富 2013-12-20 (2)A microfluidics chip for modeling haemodynamic environment in blood vessel Wenfu Zheng 2013-05-17 (3)多层细胞图案化的类血管结构的构建 2013第六届全国组织工程与再生医学大会 郑文富 2013-04-18 (4)A microfluidic chip for simulating blood vessel biomechanics, Wenfu Zheng 2012-12-03 (5)微流控刺激模型及其在生物力学研究中的应用 中国材料大会 郑文富 2012-07-13 (6)Morphological change of bone cells under fluid shear stress: a microfluidic study 中国生物医学工程学会生物材料分会第十三届学术年会 郑文富 2011-10-12

近期论文

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(1) Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer, Nature Communications, 2017, 通讯作者 (2) Composites of bacterial cellulose and small molecule-decorated gold nanoparticles for treating gram-negative bacteria-infected wounds, small, 2017, 通讯作者 (3) Construction of small-diameter vascular graft by shape-memory and self-rolling bacterial cellulose membrane, Advanced Healthcare Materials, 2017, 通讯作者 (4) Composites of Bacterial Cellulose and Small Molecule-Decorated Gold Nanoparticles for Treating Gram-Negative Bacteria-Infected Wounds, small, 2017, 通讯作者 (5) Hollow carbon nanospheres as a versatile platform for co-delivery of siRNA and chemotherapeutics, Carbon, 2017, 通讯作者 (6) Hollow carbon nanospheres for targeted delivery of chemotherapeutics in breast cancer therapy, Journal of Material Chimistry B, 2017, 通讯作者 (7) An early-stage atherosclerosis research model based on microfluidics, small, 2016, 第 1 作者 (8) Gene regulation with carbon-based siRNA conjugates for cancer therapy, Biomaterials, 2016, 第 1 作者 (9) An on-chip model for investigating the interaction between neurons and cancer cells, Ingrative biology, 2016, 通讯作者 (10) Targeted tumor delivery and controlled release of neuronal drugs with ferritin nanoparticles to regulate pancreatic cancer progression, Journal of Controlled Realease, 2016, 通讯作者 (11) Point-of-care detection of β-lactamase in milk with a universal fluorogenic probe, Analytical Chemistry, 2016, 通讯作者 (12) Investigation of tumor cell behaviors on a vascular microenvironment-mimicking microfluidic chip, Scitific Report, 2015, 通讯作者 (13) Stress-Induced Self-Assembly of Complex Three Dimensional Structures by Elastic Membranes, Small, 2014, 通讯作者 (14) Change of laminin density stimulates axon branching via growth cone myosin II mediated adhesion, Integr. Biol., 2014, 通讯作者 (15) Organs on Microfluidic Chips: a Mini Review, Sci. Chin. Chem., 2014, 第 2 作者 (16) Assembly of Functional Three-Dimensional Neuronal Networks on a Microchip, Small, 2014, 通讯作者 (17) A micropatterned coculture system for axon guidance reveals that Slit promotes axon fasciculation and regulates the expression of L1CAM, Integr. Biol., 2013, 第 2 作者 (18) Microfluidics for Manipulating Cells, Small, 2013, 第 1 作者 (19) A Strategy for the Construction of Controlled, Three-Dimensional, Multilayered, Tissue-Like Structures, Adv. Funct. Mater., 2013, 第 1 作者 (20) Precise Control of Cell Adhesion by Combination of Surface Chemistry and Soft Lithography, Adv. Healthc. Mater., 2013, 第 1 作者 (21) Engineering a 3D vascular network in hydrogel for mimicking a nephron, Lab Chip, 2013, 第 2 作者 (22) Microscale methods to assemble mammalian cells into tissue-like structures, Sci Chin Life Sci, 2012, 第 2 作者 (23) A Highly Sensitive Gold Nanoparticle-Based Assay for Acetylcholinesterase in Cerebrospinal Fluid of Transgenic Mice with Alzheimer’s Disease, Adv. Healthc Mater., 2012, 通讯作者 (24) A Rapid Screening Method for Wound Dressing by Cell-on-a-Chip Device, Adv. Healthc. Mater., 2012, 第 4 作者 (25) A microfluidic flow-stretch chip for investigating blood vessel biomechanics, Lab Chip, 2012, 第 1 作者 (26) Fluid Flow Stress Induced Contraction and Re-spread of Mesenchymal Stem Cells: a Microfluidic Study, Integr. Biol., 2012, 第 1 作者 (27) The role of calcium ions in the interactions of PrP106-126 amide with model membranes, Colloid Surface B., 2010, 第 3 作者 (28) The progress in the mechanism of anti-bacteria nanoparticles, ACTA BIOPHYSICA SINICA, 2010, 第 4 作者 (29) Biomimetic Collagen Nanofibrous Materials for Bone Tissue Engineering, Adv. Eng. Mater., 2010, 第 1 作者 (30) A simple design in PDMS-based microfluidic channels that removess bubbles in long-term on-chip culture of mammalian cells, Lab Chip, 2010, 第 1 作者 (31) Effects of lipid composition and phase on the membrane interaction of the prion peptide PrP106-126 amide, Biophys. J., 2009, 第 3 作者 (32) PrP106-126 peptide disrupts lipid membranes: influence of C-terminal amidation, Biochem. Biophys. Res. Commun., 2009, 第 1 作者 (33) PrP106-126 amide causes the semi-penetrated poration in the supported lipid bilayers, BBA-Biomembranes, 2007, 第 2 作者

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