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个人简介

2018-至今,教授, 南京大学医学院 2011-2017,副教授,南京大学医学院 2009-2011,讲师,南京大学医学院

研究领域

肿瘤免疫

近期论文

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1.Wang T*, Fan C, Yao A, Xu X, Zheng G, You Y, Jiang C, Zhao X, Hou Y, Hung M, Lin X*. The adaptor protein CARD9 protects against colon cancer by restricting mycobiota-mediated expansion of myeloid-derived suppressor cells Immunity2018,49,1-11. 2. Ren J, Ding L, Zhang D, Shi G,Xu Q, Shen S, Wang Y,Wang T*, HouY*.Carcinoma-associated fibroblasts promote the stemness and chemoresistanceof colorectal cancer by transferring exosomal lncRNA H19. Theranostics. 2018 Jun 24;8(14):3932-3948. 3. Xu H,Wang T(co-first author),Yang C, Li X, Liu G, Yang Z, Singh P, Krishnan S*, Ding D*. Supramolecular nanofibers of curcumin for highly amplified radiosensitization of colorectal cancers to ionizing radiation.Advanced Functional Material. 2018. Jan, 111-113. 4. Shi G, Li D, Ren J, Li X, Wang T*, Dou H*, Hou Y*. mTOR inhibitor INK128 attenuates dextran sodium sulfate-induced colitis by promotion of MDSCs on Treg cell expansion.J Cell Physiol. 2018 Aug 21. 5. Xu Y, Wang Y, Yao A, Xu Z, Dou H, Shen S, Hou Y, Wang T*. Low Frequency Magnetic Fields Induce Autophagy-associated Cell Death in Lung Cancer through miR-486-mediated Inhibition of Akt/mTOR Signaling Pathway.Sci Rep.2017 Sep 18;7(1):11776. 6. Xu Z, Ji J, Xu J, Li D, Shi G, Liu F, Ding L, Ren J, Dou H, Wang T*, Hou Y*. MiR-30a increases MDSC differentiation and immunosuppressive function by targeting SOCS3 in mice with B-cell lymphoma.FEBS J. 2017 Jun 12. 7. Ren J, Ding L, Xu Q, Shi G, Li X , Li X, Ji J, Zhang D, Wang Y, Wang T*, Hou Y*. LF-MF inhibits iron metabolism and suppresses lung cancer through activation of P53-miR-34a-E2F1/E2F3 pathway. Sci Rep.2017 Apr 7;7(1):749. 8. Wang T, Xu X, Xu Q, Ren J, Shen S, Fan C, Hou Y. miR-19a promotes colitis-associated colorectal cancer by regulating tumor necrosis factor alpha-induced protein 3 (TNFAIP3)-NF-κB feedback loops. Oncogene. 2017 Jun 8;36(23):3240-3251. 9. Wang T, Pan D, Zhou Z, You Y, Jiang C, Zhao X, Lin X*. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathog. 2016 Jun 9;12(6):e1005662. 10. Tang R, Xu Y, Ma F, Ren J, Shen S, Du Y, Hou Y*,Wang T*. Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT.Bioelectromagnetics.2016 Feb; 37(2): 89-98. 11. Tang R, Shen S, Zhao X, Nie Y, Xu Y, Ren J, Lv M, Hou Y*,Wang T*. Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer. Stem Cell Res Ther. 2015 Apr 13;6:71. 12. Ren J, Nie Y, Lv M, Shen S, Tang R, Xu Y, Hou Y, Zhao S*, Wang T*. Estrogen up-regulates MICA/B expression in human non-small cell lung cancer through regulation of ADAM17. Cellular & Molecular Immunology. 2015 Nov;12(6):768-76.

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