吴允昆 - 中国科学院海西研究院 -

研究领域

主要研究兴趣为生物大分子结构和功能研究以及结构基础上的药物设计和研发。

近期论文

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Wu Y, Yang Y, Ye S, Jiang Y. (2010) Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+-gated K+ Channel. Nature 466(7304):393-7. Hu J, Wu Y, Li J, Qian X, Fu Z, Sha B. (2008) The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1. BMC Structural Biology 8:3. Wu Y, Sha B. (2006). Crystal structure of yeast mitochondrial outer membrane translocon member Tom70p. Nature Structural & Molecular Biology 13(7):589-93. Li J*, Wu Y*, Qian X, Sha B. (2006). Crystal structure of yeast Sis1 peptide-binding fragment and Hsp70 Ssa1 C-terminal complex. Biochemical Journal 398(3): 353-60.（* Equal contributions） Wu Y, McCombs D, Nagy L, Delucas L, Sha B. (2006). Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p. Acta Crystallogr Sect F Struct Biol Cryst Commun. 62(Pt 3):265-7. Wu Y, Li J, Jin Z, Fu Z, Sha B. (2005). The crystal structure of the C-terminal fragment of yeast Hsp40 Ydj1 reveals novel dimerization motif for Hsp40. Journal of Molecular Biology 346(4):1005-11.