于志鹏 - 渤海大学 - 食品科学与工程学院

个人简介

于志鹏副教授，博士、硕导（食品科学专业），九三学社社员，入选辽宁省第十一批“百千万人才工程”人选，已发表科研论文80余篇，其中SCI检索论文30余篇发表在Food Chemistry、 Journal of Agricultural and Food Chemistry和Food &Function 等杂志上，50余篇中文核心期刊论文在《农业机械学报》、《吉林大学学报工学版》、《食品科学》和《食品工业科技》等刊物上；申请有关活性肽等功能因子的国家发明专利40余项，其中授权8项，完成成果转化1项。教育经历： 2012/9 ---2014/2 美国Clemson University，国家公派联培博士生 2011/9–2014/6，吉林大学，农产品加工，博士 2008/9–2011/6，吉林大学，食品科学，硕士 2004/9–2008/7，吉林大学，食品科学与工程，学士主持或参与科研项目：（1）国家自然科学基金青年项目“基于ERK1/2信号通路的蛋清肽调控代谢指纹图谱的分子机制研究”，2020-2022（主持）；（2）国家重点研发计划 “方便营养型蛋制品绿色加工关键技术研究及开发”子课题，2018-2020（主持）；（3）北京食品营养与人类健康高精尖创新“基于代谢组学的蛋清活性肽 QIGLF 调控代谢指纹图谱的分子机制研究”，2018-2019（主持）；（4）辽宁省科技厅科学事业公益研究基金“海参口服液饮品创新设计与研发”， 2016-2018（主持）；（5）教育部产学合作协同育人项目，2020-2021（主持）（6）国家自然科学基金委青年项目“基于结构糖组学的生姜糖蛋白糖基化位点与糖链空间构象解析 ”， 2017-2019（参加）；（7）国家自然科学基金委面上项目“基于Caco-2细胞模型的蛋清肽结构与完整吸收关系研究”， 2013-2016（参加）；（8）国家科技部科技支撑计划“食源性功能肽生物制备技术研究”，2012-2015（参加）；（9）国家科技部 “863”计划子课题“蛋清抗氧化肽与降压肽的生物制备技术”，2010-2012 （参加）；（10）国家自然科学基金委面上项目“蛋清ACE抑制肽的结构与体外活性相关性”， 2011-2013（参加）。授权的国家发明专利： [1] 于志鹏，赵文竹，密更，励建荣，一种利用内源酶制备蓝蛤蛋白源ACE抑制肽的方法，2018.02.02，中国，ZL201510074989.5 [2] 于志鹏，赵文竹，张宏阳，励建荣，一种蓝蛤蛋白源ACE抑制肽的制备方法，2017.10.31，中国，ZL201410857104.4 [3] 于志鹏，张宏阳，密更，赵文竹，励建荣，一种蓝蛤蛋白肽-明胶可食性膜及其制备方法，2017.09.01，中国，ZL201510401257.2 [4] 于志鹏，赵文竹，武思佳，励建荣，一种海参肽口服液及其配方，2017.05.31，中国，ZL201510150530.9 [5] 刘静波，于志鹏，赵文竹，于一丁, 蛋清蛋白血管紧张素转化酶抑制肽及其制备，2012.02.01，中国，ZL200910217782.3 获奖情况：（1）2017年入选辽宁省第十一批“百千万人才工程”万人层次人选。（2）2015年获得第二届“中国蛋品加工业十大杰出青年英才”称号。（3）2015获省科学技术奖二等奖1项“食源性生物活性肽的结构表征与生物活性基础研究”；（4）2014-2017年获得省自然学术成果奖及市自然学术成果奖多项。

研究领域

食源性活性肽的制备、纯化、结构鉴定及其体内外生物活性评价等基础研究，目前研究主要集中于ACE抑制肽（降血压活性肽）、降血糖活性肽和抗老年痴呆活性肽的酶解制备、结构鉴定、基于分子模拟的作用机制、代谢调控及稳态化保护机制研究。主持或参与科研项目：

近期论文

查看导师最新文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]Identifification and molecular mechanism of angiotensin-converting enzyme inhibitory peptides from Larimichthys crocea titin. Food Science and Human Wellness, 2020. [2]Novel aminopeptidase N inhibitory peptides derived from hen eggs: virtual screening, inhibitory activity, and action mechanisms. Food bioscience, 2020. [3]Biological Evaluation and Interaction Mechanism of beta-Site APP Cleaving Enzyme 1 inhibitory Pentapeptide from Egg Albumin. Food Science and Human Wellness, 2020. [4]Interaction mechanism of egg white- derived ACE inhibitory peptide TNGIIR with ACE and its effect on the expression of ACE and AT1 receptor. Food Science and Human Wellness, 2020. [5] Novel ACE inhibitory tripeptides from ovotransferrin using bioinformatics and peptidomics approaches. Scientific Reports,2019, IF 4.122/1区 [6] Novel membrane peptidase inhibitory peptides with activity against angiotensin converting enzyme and dipeptidyl peptidase IV identified from hen eggs. Journal of Functional Foods,2019,IF 3.197/1区 [7] Hydrolysis and Transport of Egg White-Derived Peptides in Caco‑2 Cell Monolayers and Everted Rat Sacs. Journal of Agricultural and Food Chemistry, 2019,IF 3.154/1区 [8] Novel ACE inhibitors derived from soybean proteins using in silico and in vitro studies. Journal of food biochemistry, 2019,IF 1.358/4区 [9] Virtual screening and molecular docking for exploring ACE inhibitory peptides in Larimichthys crocea nebulin protein. International Food Research Journal, 2019,IF 0.662/4区 [10] Anti-Alzheimers activity and molecular mechanism of albumin-derived peptides against AChE and BChE[J]. Food &Function, 2018, 9(2): 1173-1178. [11] The enrichment and characterization of ginger-derived glycoprotein using magnetic particles[J]. Food Chemistry, 2018, 244: 164-168. [12] Identification and the molecular mechanism of a novel myosin-derived ACE inhibitory peptide[J]. Food &Function, 2018,9(1):364-370. [13] MALDI-TOF-MS characterization of N-linked glycoprotein derived from ginger with ACE inhibitory activity[J]. Food &Function, 2018,9(5):2755-2761. [14] Identification and molecular docking study of novel angiotensin-converting enzyme inhibitory peptides from Salmo salar using in silico methods[J]. Journal of the Science of Food and Agriculture, 2018,98(10):3907-3914. [15] Novel angiotensin-converting enzyme inhibitory peptides derived from Oncorhynchus mykiss nebulin: virtual screening and in silico molecular docking study[J]. Journal of food science, 2018,83(9):2375-2383. [16] Hydrolysis and transepithelial transport of two corn gluten derived bioactive peptides in human Caco-2 cell monolayers[J]. Food Research International, 2018,106: 475-480. [17] Short- and long-term antihypertensive effect of egg protein-derived peptide QIGLF[J]. Journal of the Science of Food and Agriculture, 2017, 97(2): 551−555. [18] Importance of Terminal Amino Acid Residues to the Transport of Oligopeptides across the Caco-2 Cell Monolayer[J]. Journal of Agricultural and Food Chemistry, 2017,65 (35): 7705-7712. [19] Anxiolytic effects of ACE inhibitory peptides on the behavior of rats in an elevated plus-maze[J]. Food &Function, 2016, 7 (1):491−497. [20] Digestion and absorption of an egg white ACE inhibitory peptide in human intestinal Caco-2 cell monolayers[J]. International Journal of Food Sciences and Nutrition, 2016, 7(2):111−116 . [21] Intracellular ROS scavenging and antioxidant enzyme regulating capacities of corn gluten meal-derived antioxidant peptides in HepG2 cells[J]. Food Research International, 2016, 90: 33-41. [22] Antihypertensive effect of angiotensin-converting enzyme inhibitory peptide rvpsl on spontaneously hypertensive rats by regulating gene expression of the renin−angiotensin system[J]. Journal of Agricultural and Food Chemistry, 2014, 62:912−917. [23] Application and bioactive properties of proteins and peptides derived from hen eggs:opportunities and challenges[J]. Journal of the Science of Food and Agriculture, 2014, 94: 2839–2845. [24] Anti-diabetic activity peptides from albumin against alpha-glucosidase and alpha-amylase[J]. Food Chemistry, 2012, 135(3): 2078−2085. [25] Novel peptides derived from egg white protein inhibiting alpha-glucosidase[J]. Food Chemistry, 2011, 129(4):1376−1382. [26] Isolation and identification of angiotensin-converting enzyme inhibitory peptides from egg white protein hydrolysates[J]. Food Chemistry, 2010, 122(4): 1159−1163. [27] Characterization of ACE-inhibitory peptide associated with antioxidant and anticoagulation properties [J]. Journal of Food Science, 2011, 76(8): C1149−C1155. [28] Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein[J]. Food Chemistry, 2012, 133(2): 315−322. [29] QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein[J]. Journal of the Science of Food and Agriculture, 2011, 91(5): 921−926.

学术兼职

food chemistry，journal of agricultural and food chemistry及journal of the science of food and agriculture 等SCI 检索期刊的评审专家。